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Items: 1 to 20 of 640

1.

The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.

Delaney MK, Liu J, Zheng Y, Berndt MC, Du X.

Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2761-8. doi: 10.1161/ATVBAHA.112.254920. Epub 2012 Sep 20.

2.
3.

Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.

Yin H, Liu J, Li Z, Berndt MC, Lowell CA, Du X.

Blood. 2008 Aug 15;112(4):1139-46. doi: 10.1182/blood-2008-02-140970. Epub 2008 Jun 11.

4.

The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation.

Yin H, Stojanovic A, Hay N, Du X.

Blood. 2008 Jan 15;111(2):658-65. Epub 2007 Oct 3.

5.

Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.

Liu J, Pestina TI, Berndt MC, Jackson CW, Gartner TK.

Blood. 2005 Oct 15;106(8):2750-6. Epub 2005 Jun 28.

6.

Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway.

Cheng Z, Gao W, Fan X, Chen X, Mei H, Liu J, Luo X, Hu Y.

J Thromb Haemost. 2017 Aug;15(8):1679-1688. doi: 10.1111/jth.13755. Epub 2017 Jul 14.

8.

Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.

Wu Y, Asazuma N, Satoh K, Yatomi Y, Takafuta T, Berndt MC, Ozaki Y.

Blood. 2003 May 1;101(9):3469-76. Epub 2002 Aug 29.

PMID:
12393736
9.
10.

Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors.

Kasirer-Friede A, Cozzi MR, Mazzucato M, De Marco L, Ruggeri ZM, Shattil SJ.

Blood. 2004 May 1;103(9):3403-11. Epub 2004 Jan 15.

PMID:
14726383
11.

Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin alpha(IIb)beta(3).

Yap CL, Anderson KE, Hughan SC, Dopheide SM, Salem HH, Jackson SP.

Blood. 2002 Jan 1;99(1):151-8.

PMID:
11756165
12.

LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis.

Estevez B, Stojanovic-Terpo A, Delaney MK, O'Brien KA, Berndt MC, Ruan C, Du X.

Blood. 2013 May 30;121(22):4586-94. doi: 10.1182/blood-2012-12-470765. Epub 2013 Apr 25.

14.

Nitric oxide inhibits von Willebrand factor-mediated platelet adhesion and spreading through regulation of integrin alpha(IIb)beta(3) and myosin light chain.

Roberts W, Michno A, Aburima A, Naseem KM.

J Thromb Haemost. 2009 Dec;7(12):2106-15. doi: 10.1111/j.1538-7836.2009.03619.x. Epub 2009 Sep 18.

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High shear stress attenuates agonist-induced, glycoprotein IIb/IIIa-mediated platelet aggregation when von Willebrand factor binding to glycoprotein Ib/IX is blocked.

Iijima K, Murata M, Nakamura K, Kitaguchi T, Handa M, Watanabe K, Fujimura Y, Yoshioka A, Ikeda Y.

Biochem Biophys Res Commun. 1997 Apr 28;233(3):796-800.

PMID:
9168936
17.

Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells.

Yap CL, Hughan SC, Cranmer SL, Nesbitt WS, Rooney MM, Giuliano S, Kulkarni S, Dopheide SM, Yuan Y, Salem HH, Jackson SP.

J Biol Chem. 2000 Dec 29;275(52):41377-88.

18.

A role for p38 MAP kinase in platelet activation by von Willebrand factor.

Canobbio I, Reineri S, Sinigaglia F, Balduini C, Torti M.

Thromb Haemost. 2004 Jan;91(1):102-10.

PMID:
14691575
19.

Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis.

Lei X, Reheman A, Hou Y, Zhou H, Wang Y, Marshall AH, Liang C, Dai X, Li BX, Vanhoorelbeke K, Ni H.

Thromb Haemost. 2014 Feb;111(2):279-89. doi: 10.1160/TH13-06-0490. Epub 2013 Oct 31.

PMID:
24172860
20.

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