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Thymic function is maintained during Salmonella-induced atrophy and recovery.

Ross EA, Coughlan RE, Flores-Langarica A, Lax S, Nicholson J, Desanti GE, Marshall JL, Bobat S, Hitchcock J, White A, Jenkinson WE, Khan M, Henderson IR, Lavery GG, Buckley CD, Anderson G, Cunningham AF.

J Immunol. 2012 Nov 1;189(9):4266-74. doi: 10.4049/jimmunol.1200070. Epub 2012 Sep 19.


Discontinued postnatal thymocyte development in sphingosine 1-phosphate-lyase-deficient mice.

Weber C, Krueger A, Münk A, Bode C, Van Veldhoven PP, Gräler MH.

J Immunol. 2009 Oct 1;183(7):4292-301. doi: 10.4049/jimmunol.0901724. Epub 2009 Sep 11.


TNF-α is involved in the abnormal thymocyte migration during experimental Trypanosoma cruzi infection and favors the export of immature cells.

Pérez AR, Berbert LR, Lepletier A, Revelli S, Bottasso O, Silva-Barbosa SD, Savino W.

PLoS One. 2012;7(3):e34360. doi: 10.1371/journal.pone.0034360. Epub 2012 Mar 26.


Interferon-γ- and glucocorticoid-mediated pathways synergize to enhance death of CD4(+) CD8(+) thymocytes during Salmonella enterica serovar Typhimurium infection.

Deobagkar-Lele M, Chacko SK, Victor ES, Kadthur JC, Nandi D.

Immunology. 2013 Apr;138(4):307-21. doi: 10.1111/imm.12047.


Molecular and cellular mechanisms of Mycobacterium avium-induced thymic atrophy.

Borges M, Barreira-Silva P, Flórido M, Jordan MB, Correia-Neves M, Appelberg R.

J Immunol. 2012 Oct 1;189(7):3600-8. Epub 2012 Aug 24.


Decreased thymic output accounts for decreased naive T cell numbers in children with Down syndrome.

Bloemers BL, Bont L, de Weger RA, Otto SA, Borghans JA, Tesselaar K.

J Immunol. 2011 Apr 1;186(7):4500-7. doi: 10.4049/jimmunol.1001700. Epub 2011 Feb 23.


Chagasic thymic atrophy does not affect negative selection but results in the export of activated CD4+CD8+ T cells in severe forms of human disease.

Morrot A, Terra-Granado E, Pérez AR, Silva-Barbosa SD, Milićević NM, Farias-de-Oliveira DA, Berbert LR, De Meis J, Takiya CM, Beloscar J, Wang X, Kont V, Peterson P, Bottasso O, Savino W.

PLoS Negl Trop Dis. 2011 Aug;5(8):e1268. doi: 10.1371/journal.pntd.0001268. Epub 2011 Aug 16.


Thymic T cell export is not influenced by the peripheral T cell pool.

Gabor MJ, Scollay R, Godfrey DI.

Eur J Immunol. 1997 Nov;27(11):2986-93.


Thymic involution and thymocyte phenotypic alterations induced by murine mammary adenocarcinomas.

Fu Y, Paul RD, Wang Y, Lopez DM.

J Immunol. 1989 Dec 15;143(12):4300-7.


Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.

Dong J, Chen Y, Xu X, Jin R, Teng F, Yan F, Tang H, Li P, Sun X, Li Y, Wu H, Zhang Y, Ge Q.

PLoS One. 2013;8(2):e56378. doi: 10.1371/journal.pone.0056378. Epub 2013 Feb 11.


Defective thymic progenitor development and mature T-cell responses in a mouse model for Down syndrome.

Lorenzo LP, Shatynski KE, Clark S, Yarowsky PJ, Williams MS.

Immunology. 2013 Aug;139(4):447-58. doi: 10.1111/imm.12092.


Quantification of thymic function by measuring T cell receptor excision circles within peripheral blood and lymphoid tissues in monkeys.

Sodora DL, Douek DC, Silvestri G, Montgomery L, Rosenzweig M, Igarashi T, Bernacky B, Johnson RP, Feinberg MB, Martin MA, Koup RA.

Eur J Immunol. 2000 Apr;30(4):1145-53.


Reduced thymic output and peripheral naïve CD4 T-cell alterations in primary progressive multiple sclerosis (PPMS).

Haegert DG, Hackenbroch JD, Duszczyszyn D, Fitz-Gerald L, Zastepa E, Mason H, Lapierre Y, Antel J, Bar-Or A.

J Neuroimmunol. 2011 Apr;233(1-2):233-9. doi: 10.1016/j.jneuroim.2010.12.007. Epub 2011 Jan 26.


Role of ovarian hormones in age-associated thymic involution revisited.

Perisić M, Arsenović-Ranin N, Pilipović I, Kosec D, Pesić V, Radojević K, Leposavić G.

Immunobiology. 2010 Apr;215(4):275-93. doi: 10.1016/j.imbio.2009.06.012. Epub 2009 Jul 4.


The thymus is a common target organ in infectious diseases.

Savino W.

PLoS Pathog. 2006 Jun;2(6):e62. Review.


The biology of recent thymic emigrants.

Fink PJ.

Annu Rev Immunol. 2013;31:31-50. doi: 10.1146/annurev-immunol-032712-100010. Epub 2012 Nov 1. Review.


Social stress and T cell maturation in male rats: transient and persistent alterations in thymic function.

Engler H, Stefanski V.

Psychoneuroendocrinology. 2003 Nov;28(8):951-69.


Characterization of thymic involution induced by murine cytomegalovirus infection.

Price P, Olver SD, Gibbons AE, Teo HK, Shellam GR.

Immunol Cell Biol. 1993 Jun;71 ( Pt 3):155-65.

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