Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 130

1.

AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence.

Wang Z, Lisowski L, Finegold MJ, Nakai H, Kay MA, Grompe M.

Mol Ther. 2012 Oct;20(10):1902-11. doi: 10.1038/mt.2012.157. Epub 2012 Sep 18.

2.

Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.

Lisowski L, Lau A, Wang Z, Zhang Y, Zhang F, Grompe M, Kay MA.

Mol Ther. 2012 Oct;20(10):1912-23. doi: 10.1038/mt.2012.164. Epub 2012 Sep 18.

4.
5.

Hybrid adeno-associated viral vectors utilizing transposase-mediated somatic integration for stable transgene expression in human cells.

Zhang W, Solanki M, Müther N, Ebel M, Wang J, Sun C, Izsvak Z, Ehrhardt A.

PLoS One. 2013 Oct 8;8(10):e76771. doi: 10.1371/journal.pone.0076771. eCollection 2013.

6.
7.

Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis.

Philpott NJ, Giraud-Wali C, Dupuis C, Gomos J, Hamilton H, Berns KI, Falck-Pedersen E.

J Virol. 2002 Jun;76(11):5411-21.

8.

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Lisowski L, Dane AP, Chu K, Zhang Y, Cunningham SC, Wilson EM, Nygaard S, Grompe M, Alexander IE, Kay MA.

Nature. 2014 Feb 20;506(7488):382-6. doi: 10.1038/nature12875. Epub 2013 Dec 25.

9.

Safety of liver gene transfer following peripheral intravascular delivery of adeno-associated virus (AAV)-5 and AAV-6 in a large animal model.

Favaro P, Finn JD, Siner JI, Wright JF, High KA, Arruda VR.

Hum Gene Ther. 2011 Jul;22(7):843-52. doi: 10.1089/hum.2010.155. Epub 2011 Mar 8.

10.
11.

Enhancing transduction of the liver by adeno-associated viral vectors.

Nathwani AC, Cochrane M, McIntosh J, Ng CY, Zhou J, Gray JT, Davidoff AM.

Gene Ther. 2009 Jan;16(1):60-9. doi: 10.1038/gt.2008.137. Epub 2008 Aug 14.

12.

Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids.

Chamberlain K, Riyad JM, Weber T.

Hum Gene Ther Methods. 2016 Feb;27(1):1-12. doi: 10.1089/hgtb.2015.140. Review.

13.

AAV serotype 2 vectors preferentially integrate into active genes in mice.

Nakai H, Montini E, Fuess S, Storm TA, Grompe M, Kay MA.

Nat Genet. 2003 Jul;34(3):297-302.

PMID:
12778174
14.

Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.

Jayandharan GR, Zhong L, Sack BK, Rivers AE, Li M, Li B, Herzog RW, Srivastava A.

Hum Gene Ther. 2010 Mar;21(3):271-83. doi: 10.1089/hum.2009.100.

15.

Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector.

Mingozzi F, Schüttrumpf J, Arruda VR, Liu Y, Liu YL, High KA, Xiao W, Herzog RW.

J Virol. 2002 Oct;76(20):10497-502.

16.

[Integration of AAV vectors and insertional mutagenesis].

Rossi A, Salvetti A.

Med Sci (Paris). 2016 Feb;32(2):167-74. doi: 10.1051/medsci/20163202010. Epub 2016 Mar 2. Review. French.

17.

Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro.

Yang CC, Xiao X, Zhu X, Ansardi DC, Epstein ND, Frey MR, Matera AG, Samulski RJ.

J Virol. 1997 Dec;71(12):9231-47.

18.
19.

Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.

Lieber A, Steinwaerder DS, Carlson CA, Kay MA.

J Virol. 1999 Nov;73(11):9314-24.

20.

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors.

Snyder RO, Miao CH, Patijn GA, Spratt SK, Danos O, Nagy D, Gown AM, Winther B, Meuse L, Cohen LK, Thompson AR, Kay MA.

Nat Genet. 1997 Jul;16(3):270-6.

PMID:
9207793

Supplemental Content

Support Center