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Items: 1 to 20 of 140

1.

A p53-Pax2 pathway in kidney development: implications for nephrogenesis.

Saifudeen Z, Liu J, Dipp S, Yao X, Li Y, McLaughlin N, Aboudehen K, El-Dahr SS.

PLoS One. 2012;7(9):e44869. doi: 10.1371/journal.pone.0044869. Epub 2012 Sep 12.

2.

Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2.

Dziarmaga A, Hueber PA, Iglesias D, Hache N, Jeffs A, Gendron N, Mackenzie A, Eccles M, Goodyer P.

Am J Physiol Renal Physiol. 2006 Oct;291(4):F913-20. Epub 2006 May 30.

3.

Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice.

Porteous S, Torban E, Cho NP, Cunliffe H, Chua L, McNoe L, Ward T, Souza C, Gus P, Giugliani R, Sato T, Yun K, Favor J, Sicotte M, Goodyer P, Eccles M.

Hum Mol Genet. 2000 Jan 1;9(1):1-11.

PMID:
10587573
4.

Mdm2 is required for maintenance of the nephrogenic niche.

Hilliard SA, Yao X, El-Dahr SS.

Dev Biol. 2014 Mar 1;387(1):1-14. doi: 10.1016/j.ydbio.2014.01.009. Epub 2014 Jan 17.

5.

Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice.

Dziarmaga A, Eccles M, Goodyer P.

J Am Soc Nephrol. 2006 Jun;17(6):1568-75. Epub 2006 May 3.

6.

PAX2 activates WNT4 expression during mammalian kidney development.

Torban E, Dziarmaga A, Iglesias D, Chu LL, Vassilieva T, Little M, Eccles M, Discenza M, Pelletier J, Goodyer P.

J Biol Chem. 2006 May 5;281(18):12705-12. Epub 2005 Dec 19.

7.

p53 Enables metabolic fitness and self-renewal of nephron progenitor cells.

Li Y, Liu J, Li W, Brown A, Baddoo M, Li M, Carroll T, Oxburgh L, Feng Y, Saifudeen Z.

Development. 2015 Apr 1;142(7):1228-41. doi: 10.1242/dev.111617.

8.

Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney.

Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M.

J Am Soc Nephrol. 2007 Apr;18(4):1121-9. Epub 2007 Feb 21.

9.

Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk.

Clark P, Dziarmaga A, Eccles M, Goodyer P.

J Am Soc Nephrol. 2004 Feb;15(2):299-305.

10.

Genome-wide analysis of gestational gene-environment interactions in the developing kidney.

Yan L, Yao X, Bachvarov D, Saifudeen Z, El-Dahr SS.

Physiol Genomics. 2014 Sep 1;46(17):655-70. doi: 10.1152/physiolgenomics.00035.2014. Epub 2014 Jul 8.

11.

Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome.

Dziarmaga A, Clark P, Stayner C, Julien JP, Torban E, Goodyer P, Eccles M.

J Am Soc Nephrol. 2003 Nov;14(11):2767-74.

12.

Epigenetic States of nephron progenitors and epithelial differentiation.

Adli M, Parlak M, Li Y, El-Dahr SS.

J Cell Biochem. 2015 Jun;116(6):893-902. doi: 10.1002/jcb.25048. Review.

13.

WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2.

Discenza MT, He S, Lee TH, Chu LL, Bolon B, Goodyer P, Eccles M, Pelletier J.

Oncogene. 2003 Nov 6;22(50):8145-55.

PMID:
14603255
14.

Genome-wide analysis of the p53 gene regulatory network in the developing mouse kidney.

Li Y, Liu J, McLaughlin N, Bachvarov D, Saifudeen Z, El-Dahr SS.

Physiol Genomics. 2013 Oct 16;45(20):948-64. doi: 10.1152/physiolgenomics.00113.2013. Epub 2013 Sep 3.

15.

Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease.

Stayner C, Iglesias DM, Goodyer PR, Ellis L, Germino G, Zhou J, Eccles MR.

Hum Mol Genet. 2006 Dec 15;15(24):3520-8. Epub 2006 Nov 2. Erratum in: Hum Mol Genet. 2009 Apr 15;18(8):1543.

PMID:
17082250
16.

Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage.

Clarke JC, Patel SR, Raymond RM Jr, Andrew S, Robinson BG, Dressler GR, Brophy PD.

Hum Mol Genet. 2006 Dec 1;15(23):3420-8. Epub 2006 Oct 17.

PMID:
17047028
17.

Prorenin receptor is critical for nephron progenitors.

Song R, Preston G, Kidd L, Bushnell D, Sims-Lucas S, Bates CM, Yosypiv IV.

Dev Biol. 2016 Jan 15;409(2):382-91. doi: 10.1016/j.ydbio.2015.11.024. Epub 2015 Dec 3.

18.

Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis.

Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S.

Hum Mol Genet. 2012 Jul 15;21(14):3143-55. doi: 10.1093/hmg/dds141. Epub 2012 Apr 17.

PMID:
22511595
19.

Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis.

Xu J, Liu H, Chai OH, Lan Y, Jiang R.

PLoS One. 2016 Jul 21;11(7):e0159597. doi: 10.1371/journal.pone.0159597. eCollection 2016.

20.

The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype.

Cross SH, McKie L, West K, Coghill EL, Favor J, Bhattacharya S, Brown SD, Jackson IJ.

Hum Mol Genet. 2011 Jan 15;20(2):223-34. doi: 10.1093/hmg/ddq457. Epub 2010 Oct 13.

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