Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 81

1.

Are alsin and spartin novel interaction partners?

Çobanoğlu G, Ozansoy M, Başak AN.

Biochem Biophys Res Commun. 2012 Oct 12;427(1):1-4. doi: 10.1016/j.bbrc.2012.08.103. Epub 2012 Sep 7.

PMID:
22982304
2.

Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene.

Eymard-Pierre E, Lesca G, Dollet S, Santorelli FM, di Capua M, Bertini E, Boespflug-Tanguy O.

Am J Hum Genet. 2002 Sep;71(3):518-27. Epub 2002 Jul 26.

3.

Infantile-onset ascending hereditary spastic paraplegia with bulbar involvement due to the novel ALS2 mutation c.2761C>T.

Wakil SM, Ramzan K, Abuthuraya R, Hagos S, Al-Dossari H, Al-Omar R, Murad H, Chedrawi A, Al-Hassnan ZN, Finsterer J, Bohlega S.

Gene. 2014 Feb 15;536(1):217-20. doi: 10.1016/j.gene.2013.11.043. Epub 2013 Dec 4.

PMID:
24315819
4.

The first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological function.

Panzeri C, De Palma C, Martinuzzi A, Daga A, De Polo G, Bresolin N, Miller CC, Tudor EL, Clementi E, Bassi MT.

Brain. 2006 Jul;129(Pt 7):1710-9. Epub 2006 May 2.

PMID:
16670179
5.

Molecular and cellular function of ALS2/alsin: implication of membrane dynamics in neuronal development and degeneration.

Hadano S, Kunita R, Otomo A, Suzuki-Utsunomiya K, Ikeda JE.

Neurochem Int. 2007 Jul-Sep;51(2-4):74-84. Epub 2007 May 4. Review.

PMID:
17566607
6.

Astrocytic protection of spinal motor neurons but not cortical neurons against loss of Als2/alsin function.

Jacquier A, Bellouze S, Blanchard S, Bohl D, Haase G.

Hum Mol Genet. 2009 Jun 15;18(12):2127-39. doi: 10.1093/hmg/ddp136. Epub 2009 Mar 20.

PMID:
19304783
7.

ALS2/alsin knockout mice and motor neuron diseases.

Cai H, Shim H, Lai C, Xie C, Lin X, Yang WJ, Chandran J.

Neurodegener Dis. 2008;5(6):359-66. doi: 10.1159/000151295. Epub 2008 Aug 20. Review.

8.

Alfa-class prefoldin protein UXT is a novel interacting partner of Amyotrophic Lateral Sclerosis 2 (Als2) protein.

Enunlu I, Ozansoy M, Basak AN.

Biochem Biophys Res Commun. 2011 Sep 30;413(3):471-5. doi: 10.1016/j.bbrc.2011.08.121. Epub 2011 Sep 1.

PMID:
21907703
9.

Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms.

Gautam M, Jara JH, Sekerkova G, Yasvoina MV, Martina M, Özdinler PH.

Hum Mol Genet. 2016 Mar 15;25(6):1074-87. doi: 10.1093/hmg/ddv631. Epub 2016 Jan 10.

10.

Alsin and the molecular pathways of amyotrophic lateral sclerosis.

Chandran J, Ding J, Cai H.

Mol Neurobiol. 2007 Dec;36(3):224-31. Epub 2007 Jul 10. Review.

11.

Identification of two novel ALS2 mutations in infantile-onset ascending hereditary spastic paraplegia.

Daud S, Kakar N, Goebel I, Hashmi AS, Yaqub T, Nürnberg G, Nürnberg P, Morris-Rosendahl DJ, Wasim M, Volk AE, Kubisch C, Ahmad J, Borck G.

Amyotroph Lateral Scler Frontotemporal Degener. 2016;17(3-4):260-5. doi: 10.3109/21678421.2015.1125501. Epub 2016 Jan 11.

PMID:
26751646
12.

Alsin is partially associated with centrosome in human cells.

Millecamps S, Gentil BJ, Gros-Louis F, Rouleau G, Julien JP.

Biochim Biophys Acta. 2005 Aug 15;1745(1):84-100. Epub 2005 Jan 19.

13.

Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants.

Kanekura K, Hashimoto Y, Niikura T, Aiso S, Matsuoka M, Nishimoto I.

J Biol Chem. 2004 Apr 30;279(18):19247-56. Epub 2004 Feb 16.

14.

Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish.

Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA.

Hum Mol Genet. 2008 Sep 1;17(17):2691-702. doi: 10.1093/hmg/ddn171. Epub 2008 Jun 16.

PMID:
18558633
15.

Primary lateral sclerosis, hereditary spastic paraplegia, and mutations in the alsin gene: historical background for the first International Conference.

Rowland LP.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Jun;6(2):67-76. Review. No abstract available.

PMID:
16036429
16.

The first nonsense mutation in alsin results in a homogeneous phenotype of infantile-onset ascending spastic paralysis with bulbar involvement in two siblings.

Devon RS, Helm JR, Rouleau GA, Leitner Y, Lerman-Sagie T, Lev D, Hayden MR.

Clin Genet. 2003 Sep;64(3):210-5.

PMID:
12919135
17.

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.

Yang Y, Hentati A, Deng HX, Dabbagh O, Sasaki T, Hirano M, Hung WY, Ouahchi K, Yan J, Azim AC, Cole N, Gascon G, Yagmour A, Ben-Hamida M, Pericak-Vance M, Hentati F, Siddique T.

Nat Genet. 2001 Oct;29(2):160-5.

PMID:
11586297
18.

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, Zhu JJ, Cai H.

J Neurosci. 2006 Nov 8;26(45):11798-806.

19.

The Rab5 activator ALS2/alsin acts as a novel Rac1 effector through Rac1-activated endocytosis.

Kunita R, Otomo A, Mizumura H, Suzuki-Utsunomiya K, Hadano S, Ikeda JE.

J Biol Chem. 2007 Jun 1;282(22):16599-611. Epub 2007 Apr 4.

20.

Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood.

Devon RS, Schwab C, Topp JD, Orban PC, Yang YZ, Pape TD, Helm JR, Davidson TL, Rogers DA, Gros-Louis F, Rouleau G, Horazdovsky BF, Leavitt BR, Hayden MR.

Neurobiol Dis. 2005 Mar;18(2):243-57.

PMID:
15686953

Supplemental Content

Support Center