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Items: 1 to 20 of 317

1.

Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner.

Moon DO, Asami Y, Long H, Jang JH, Bae EY, Kim BY, Choi YH, Kang CH, Ahn JS, Kim GY.

Toxicol In Vitro. 2013 Feb;27(1):257-63. doi: 10.1016/j.tiv.2012.09.001. Epub 2012 Sep 12.

PMID:
22982206
2.

Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: involvement of ROS-dependent ER-stress.

Moon DO, Park SY, Choi YH, Ahn JS, Kim GY.

Biochem Pharmacol. 2011 Dec 1;82(11):1641-50. doi: 10.1016/j.bcp.2011.08.019. Epub 2011 Aug 31.

PMID:
21903093
4.

5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.

Yang JF, Cao JG, Tian L, Liu F.

Cancer Chemother Pharmacol. 2012 Jan;69(1):195-206. doi: 10.1007/s00280-011-1686-9. Epub 2011 Jun 10.

PMID:
21660448
5.
6.

Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.

Taniguchi H, Yoshida T, Horinaka M, Yasuda T, Goda AE, Konishi M, Wakada M, Kataoka K, Yoshikawa T, Sakai T.

Cancer Res. 2008 Nov 1;68(21):8918-27. doi: 10.1158/0008-5472.CAN-08-1120.

7.

Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation.

Kim IY, Kang YJ, Yoon MJ, Kim EH, Kim SU, Kwon TK, Kim IA, Choi KS.

Neuro Oncol. 2011 Mar;13(3):267-79. doi: 10.1093/neuonc/noq195. Epub 2011 Feb 3.

9.

Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5.

Chen CY, Yiin SJ, Hsu JL, Wang WC, Lin SC, Chern CL.

J Agric Food Chem. 2012 Apr 4;60(13):3533-9. doi: 10.1021/jf2051224. Epub 2012 Mar 21.

PMID:
22400995
10.

Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells.

Teng Y, Gao M, Wang J, Kong Q, Hua H, Luo T, Jiang Y.

Cell Death Dis. 2014 Feb 13;5:e1060. doi: 10.1038/cddis.2014.24.

11.

Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.

Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T.

Mol Cancer Res. 2008 Dec;6(12):1852-60. doi: 10.1158/1541-7786.MCR-08-0012.

12.

Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.

Sung B, Prasad S, Ravindran J, Yadav VR, Aggarwal BB.

Free Radic Biol Med. 2012 Nov 15;53(10):1977-87. doi: 10.1016/j.freeradbiomed.2012.08.012. Epub 2012 Aug 15.

13.

Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.

Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF.

Chem Res Toxicol. 2015 Aug 17;28(8):1574-83. doi: 10.1021/acs.chemrestox.5b00150. Epub 2015 Jul 31.

PMID:
26203587
14.
15.

PKCδ regulates death receptor 5 expression induced by PS-341 through ATF4-ATF3/CHOP axis in human lung cancer cells.

Xu L, Su L, Liu X.

Mol Cancer Ther. 2012 Oct;11(10):2174-82. doi: 10.1158/1535-7163.MCT-12-0602. Epub 2012 Jul 30.

16.

Modulation of CCAAT/enhancer binding protein homologous protein (CHOP)-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

Tian X, Ye J, Alonso-Basanta M, Hahn SM, Koumenis C, Dorsey JF.

J Biol Chem. 2011 Aug 19;286(33):29408-16. doi: 10.1074/jbc.M110.197665. Epub 2011 Jun 22.

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The herbal compound cryptotanshinone restores sensitivity in cancer cells that are resistant to the tumor necrosis factor-related apoptosis-inducing ligand.

Tse AK, Chow KY, Cao HH, Cheng CY, Kwan HY, Yu H, Zhu GY, Wu YC, Fong WF, Yu ZL.

J Biol Chem. 2013 Oct 11;288(41):29923-33. doi: 10.1074/jbc.M113.483909. Epub 2013 Aug 28.

20.

Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation.

Jung EM, Park JW, Choi KS, Park JW, Lee HI, Lee KS, Kwon TK.

Carcinogenesis. 2006 Oct;27(10):2008-17. Epub 2006 Apr 12.

PMID:
16613838

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