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Identification of novel and cross-species seroreactive proteins from Bacillus anthracis using a ligation-independent cloning-based, SOS-inducible expression system.

McWilliams BD, Palzkill T, Weinstock GM, Petrosino JF.

Microb Pathog. 2012 Nov-Dec;53(5-6):250-8. doi: 10.1016/j.micpath.2012.08.006. Epub 2012 Sep 10.


Search for Bacillus anthracis potential vaccine candidates by a functional genomic-serologic screen.

Gat O, Grosfeld H, Ariel N, Inbar I, Zaide G, Broder Y, Zvi A, Chitlaru T, Altboum Z, Stein D, Cohen S, Shafferman A.

Infect Immun. 2006 Jul;74(7):3987-4001.


Anthrax protective antigen delivered by Salmonella enterica serovar Typhi Ty21a protects mice from a lethal anthrax spore challenge.

Osorio M, Wu Y, Singh S, Merkel TJ, Bhattacharyya S, Blake MS, Kopecko DJ.

Infect Immun. 2009 Apr;77(4):1475-82. doi: 10.1128/IAI.00828-08. Epub 2009 Jan 29.


Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax.

Skoble J, Beaber JW, Gao Y, Lovchik JA, Sower LE, Liu W, Luckett W, Peterson JW, Calendar R, Portnoy DA, Lyons CR, Dubensky TW Jr.

Infect Immun. 2009 Apr;77(4):1649-63. doi: 10.1128/IAI.00530-08. Epub 2009 Jan 21.


[Immunogenicity of the recombinant Bacillus strains with cloned gene of biosynthesis of protective antigen against Bacillus anthracis].

Mikshis NI, Kudriavtseva OM, Bolothikova MF, Shulepov DV, Novikova LV, Popov IuA, Shchukovskaia TN, Drozdov IG, Kutyrev VV.

Mol Gen Mikrobiol Virusol. 2007;(3):15-21. Russian.


Plasmid-based vaccination with candidate anthrax vaccine antigens induces durable type 1 and type 2 T-helper immune responses.

Zhang Y, Qiu J, Zhou Y, Farhangfar F, Hester J, Lin AY, Decker WK.

Vaccine. 2008 Jan 30;26(5):614-22. doi: 10.1016/j.vaccine.2007.11.072. Epub 2007 Dec 18.


Immunogenicity of recombinant protective antigen and efficacy against aerosol challenge with anthrax.

Williamson ED, Hodgson I, Walker NJ, Topping AW, Duchars MG, Mott JM, Estep J, Lebutt C, Flick-Smith HC, Jones HE, Li H, Quinn CP.

Infect Immun. 2005 Sep;73(9):5978-87.


Bridging non-human primate correlates of protection to reassess the Anthrax Vaccine Adsorbed booster schedule in humans.

Schiffer JM, Chen L, Dalton S, Niemuth NA, Sabourin CL, Quinn CP.

Vaccine. 2015 Jul 17;33(31):3709-16. doi: 10.1016/j.vaccine.2015.05.091. Epub 2015 Jun 10.


Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.

Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH.

PLoS One. 2015 Jul 24;10(7):e0130952. doi: 10.1371/journal.pone.0130952. eCollection 2015.


A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores.

Hermanson G, Whitlow V, Parker S, Tonsky K, Rusalov D, Ferrari M, Lalor P, Komai M, Mere R, Bell M, Brenneman K, Mateczun A, Evans T, Kaslow D, Galloway D, Hobart P.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13601-6. Epub 2004 Sep 1.


Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis.

Stokes MG, Titball RW, Neeson BN, Galen JE, Walker NJ, Stagg AJ, Jenner DC, Thwaite JE, Nataro JP, Baillie LW, Atkins HS.

Infect Immun. 2007 Apr;75(4):1827-34. Epub 2006 Dec 4.


Efficacy and immunogenicity of single-dose AdVAV intranasal anthrax vaccine compared to anthrax vaccine absorbed in an aerosolized spore rabbit challenge model.

Krishnan V, Andersen BH, Shoemaker C, Sivko GS, Tordoff KP, Stark GV, Zhang J, Feng T, Duchars M, Roberts MS.

Clin Vaccine Immunol. 2015 Apr;22(4):430-9. doi: 10.1128/CVI.00690-14. Epub 2015 Feb 11.


The role of antibodies to Bacillus anthracis and anthrax toxin components in inhibiting the early stages of infection by anthrax spores.

Welkos S, Little S, Friedlander A, Fritz D, Fellows P.

Microbiology. 2001 Jun;147(Pt 6):1677-85.


Vaccination of rhesus macaques with the anthrax vaccine adsorbed vaccine produces a serum antibody response that effectively neutralizes receptor-bound protective antigen in vitro.

Clement KH, Rudge TL Jr, Mayfield HJ, Carlton LA, Hester A, Niemuth NA, Sabourin CL, Brys AM, Quinn CP.

Clin Vaccine Immunol. 2010 Nov;17(11):1753-62. doi: 10.1128/CVI.00174-10. Epub 2010 Aug 25.


Identification of the pXO1 plasmid in attenuated Bacillus anthracis vaccine strains.

Liang X, Zhang H, Zhang E, Wei J, Li W, Wang B, Dong S, Zhu J.

Virulence. 2016 Jul 3;7(5):578-86. doi: 10.1080/21505594.2016.1164366. Epub 2016 Mar 30.


Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant.

Park YS, Lee JH, Hung CF, Wu TC, Kim TW.

Infect Immun. 2008 May;76(5):1952-9. doi: 10.1128/IAI.01722-07. Epub 2008 Feb 19.


A plant based protective antigen [PA(dIV)] vaccine expressed in chloroplasts demonstrates protective immunity in mice against anthrax.

Gorantala J, Grover S, Goel D, Rahi A, Jayadev Magani SK, Chandra S, Bhatnagar R.

Vaccine. 2011 Jun 15;29(27):4521-33. doi: 10.1016/j.vaccine.2011.03.082. Epub 2011 Apr 17.


Genome-based bioinformatic selection of chromosomal Bacillus anthracis putative vaccine candidates coupled with proteomic identification of surface-associated antigens.

Ariel N, Zvi A, Makarova KS, Chitlaru T, Elhanany E, Velan B, Cohen S, Friedlander AM, Shafferman A.

Infect Immun. 2003 Aug;71(8):4563-79.


Protection of mice against challenge with Bacillus anthracis STI spores after DNA vaccination.

Hahn UK, Alex M, Czerny CP, Böhm R, Beyer W.

Int J Med Microbiol. 2004 Jul;294(1):35-44.


Presentation of peptides from Bacillus anthracis protective antigen on Tobacco Mosaic Virus as an epitope targeted anthrax vaccine.

McComb RC, Ho CL, Bradley KA, Grill LK, Martchenko M.

Vaccine. 2015 Nov 27;33(48):6745-51. doi: 10.1016/j.vaccine.2015.10.075. Epub 2015 Oct 26.


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