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Items: 1 to 20 of 97

1.

Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1.

Zhou T, Cong S, Sun S, Sun H, Zou R, Wang S, Wang C, Jiao J, Goto K, Nawata H, Yanase T, Zhao Y.

Mol Cell Endocrinol. 2013 Jan 5;365(1):36-43. doi: 10.1016/j.mce.2012.09.001. Epub 2012 Sep 10.

PMID:
22975079
3.

Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription.

Takeshita A, Koibuchi N, Oka J, Taguchi M, Shishiba Y, Ozawa Y.

Eur J Endocrinol. 2001 Oct;145(4):513-7.

4.

Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor.

Takeshita A, Igarashi-Migitaka J, Nishiyama K, Takahashi H, Takeuchi Y, Koibuchi N.

Toxicol Sci. 2011 Oct;123(2):460-70. doi: 10.1093/toxsci/kfr178. Epub 2011 Jul 8.

PMID:
21742782
5.

Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics.

Takeshita A, Taguchi M, Koibuchi N, Ozawa Y.

J Biol Chem. 2002 Sep 6;277(36):32453-8. Epub 2002 Jun 18.

6.

Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.

Luckert C, Ehlers A, Buhrke T, Seidel A, Lampen A, Hessel S.

Toxicol Lett. 2013 Oct 24;222(2):180-8. doi: 10.1016/j.toxlet.2013.06.243. Epub 2013 Jul 8.

PMID:
23845848
7.

Pregnane X receptor mediated-transcription regulation of CYP3A by glycyrrhizin: a possible mechanism for its hepatoprotective property against lithocholic acid-induced injury.

Wang YG, Zhou JM, Ma ZC, Li H, Liang QD, Tan HL, Xiao CR, Zhang BL, Gao Y.

Chem Biol Interact. 2012 Oct 25;200(1):11-20. doi: 10.1016/j.cbi.2012.08.023. Epub 2012 Sep 13.

PMID:
22982774
8.

Mitotane induces CYP3A4 expression via activation of the steroid and xenobiotic receptor.

Takeshita A, Igarashi-Migitaka J, Koibuchi N, Takeuchi Y.

J Endocrinol. 2013 Feb 15;216(3):297-305. doi: 10.1530/JOE-12-0297. Print 2013 Mar.

9.

Interaction of silencing mediator for retinoid and thyroid receptors with steroid and xenobiotic receptor on multidrug resistance 1 promoter.

Hirooka-Masui K, Lesmana R, Iwasaki T, Xu M, Hayasaka K, Haraguchi M, Takeshita A, Shimokawa N, Yamamoto K, Koibuchi N.

Life Sci. 2013 May 20;92(17-19):911-5. doi: 10.1016/j.lfs.2013.03.007. Epub 2013 Apr 3.

PMID:
23562850
10.

Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence.

Igarashi K, Kitajima S, Aisaki K, Tanemura K, Taquahashi Y, Moriyama N, Ikeno E, Matsuda N, Saga Y, Blumberg B, Kanno J.

J Toxicol Sci. 2012;37(2):373-80.

11.

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia.

Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE.

J Clin Invest. 2006 Jun;116(6):1703-12. Epub 2006 May 11.

12.

Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator.

Watanabe K, Sakurai K, Tsuchiya Y, Yamazoe Y, Yoshinari K.

Biochem Pharmacol. 2013 Aug 1;86(3):428-36. doi: 10.1016/j.bcp.2013.05.016. Epub 2013 May 31.

PMID:
23732298
13.

Molecular mechanism of nuclear translocation of an orphan nuclear receptor, SXR.

Kawana K, Ikuta T, Kobayashi Y, Gotoh O, Takeda K, Kawajiri K.

Mol Pharmacol. 2003 Mar;63(3):524-31.

14.
16.

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.

Xie W, Barwick JL, Simon CM, Pierce AM, Safe S, Blumberg B, Guzelian PS, Evans RM.

Genes Dev. 2000 Dec 1;14(23):3014-23.

17.

Endocrine disrupting chemicals, phthalic acid and nonylphenol, activate Pregnane X receptor-mediated transcription.

Masuyama H, Hiramatsu Y, Kunitomi M, Kudo T, MacDonald PN.

Mol Endocrinol. 2000 Mar;14(3):421-8.

PMID:
10707959
18.

The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators.

Pacyniak EK, Cheng X, Cunningham ML, Crofton K, Klaassen CD, Guo GL.

Toxicol Sci. 2007 May;97(1):94-102. Epub 2007 Feb 25.

PMID:
17324954
19.

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM.

Nature. 2000 Jul 27;406(6794):435-9.

PMID:
10935643
20.

Tamoxifen activates CYP3A4 and MDR1 genes through steroid and xenobiotic receptor in breast cancer cells.

Nagaoka R, Iwasaki T, Rokutanda N, Takeshita A, Koibuchi Y, Horiguchi J, Shimokawa N, Iino Y, Morishita Y, Koibuchi N.

Endocrine. 2006 Dec;30(3):261-8.

PMID:
17526937

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