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Items: 1 to 20 of 412

1.

Double-stranded RNA induces biphasic STAT1 phosphorylation by both type I interferon (IFN)-dependent and type I IFN-independent pathways.

Dempoya J, Matsumiya T, Imaizumi T, Hayakari R, Xing F, Yoshida H, Okumura K, Satoh K.

J Virol. 2012 Dec;86(23):12760-9. doi: 10.1128/JVI.01881-12. Epub 2012 Sep 12.

2.

Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.

Dong LW, Kong XN, Yan HX, Yu LX, Chen L, Yang W, Liu Q, Huang DD, Wu MC, Wang HY.

Mol Immunol. 2008 Jun;45(11):3025-35. doi: 10.1016/j.molimm.2008.03.012. Epub 2008 May 8.

PMID:
18471880
3.
4.

Non-Canonical Role of IKKα in the Regulation of STAT1 Phosphorylation in Antiviral Signaling.

Xing F, Matsumiya T, Shiba Y, Hayakari R, Yoshida H, Imaizumi T.

PLoS One. 2016 Dec 19;11(12):e0168696. doi: 10.1371/journal.pone.0168696. eCollection 2016.

5.

Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN.

DeWitte-Orr SJ, Mehta DR, Collins SE, Suthar MS, Gale M Jr, Mossman KL.

J Immunol. 2009 Nov 15;183(10):6545-53. doi: 10.4049/jimmunol.0900867. Epub 2009 Oct 28.

6.

Direct effect of dsRNA mimetics on cancer cells induces endogenous IFN-β production capable of improving dendritic cell function.

Gatti G, Nuñez NG, Nocera DA, Dejager L, Libert C, Giraudo C, Maccioni M.

Eur J Immunol. 2013 Jul;43(7):1849-61. doi: 10.1002/eji.201242902. Epub 2013 May 28.

7.

Functional evolution of the TICAM-1 pathway for extrinsic RNA sensing.

Seya T, Matsumoto M, Ebihara T, Oshiumi H.

Immunol Rev. 2009 Jan;227(1):44-53. doi: 10.1111/j.1600-065X.2008.00723.x. Review.

PMID:
19120474
8.

The RNA-activated protein kinase enhances the induction of interferon-beta and apoptosis mediated by cytoplasmic RNA sensors.

McAllister CS, Samuel CE.

J Biol Chem. 2009 Jan 16;284(3):1644-51. doi: 10.1074/jbc.M807888200. Epub 2008 Nov 20.

9.

SOCS1-negative feedback of STAT1 activation is a key pathway in the dsRNA-induced innate immune response of human keratinocytes.

Dai X, Sayama K, Yamasaki K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yahata Y, Yang L, Yoshimura A, Hashimoto K.

J Invest Dermatol. 2006 Jul;126(7):1574-81. Epub 2006 Apr 20.

10.

Inhibition of antiviral innate immunity by birnavirus VP3 protein via blockage of viral double-stranded RNA binding to the host cytoplasmic RNA detector MDA5.

Ye C, Jia L, Sun Y, Hu B, Wang L, Lu X, Zhou J.

J Virol. 2014 Oct;88(19):11154-65. doi: 10.1128/JVI.01115-14. Epub 2014 Jul 16.

11.

Expression and function of RIG-I in oral keratinocytes and fibroblasts.

Ohta K, Fukui A, Shigeishi H, Ishida Y, Nishi H, Tobiume K, Takechi M, Kamata N.

Cell Physiol Biochem. 2014;34(5):1556-65. doi: 10.1159/000366359. Epub 2014 Oct 27.

12.

LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA.

Childs KS, Randall RE, Goodbourn S.

PLoS One. 2013 May 9;8(5):e64202. doi: 10.1371/journal.pone.0064202. Print 2013.

13.

Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cells.

Hirata Y, Broquet AH, Menchén L, Kagnoff MF.

J Immunol. 2007 Oct 15;179(8):5425-32.

14.

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.

Sasai M, Shingai M, Funami K, Yoneyama M, Fujita T, Matsumoto M, Seya T.

J Immunol. 2006 Dec 15;177(12):8676-83.

15.

The clathrin-mediated endocytic pathway participates in dsRNA-induced IFN-beta production.

Itoh K, Watanabe A, Funami K, Seya T, Matsumoto M.

J Immunol. 2008 Oct 15;181(8):5522-9.

16.

Double-stranded RNA-induced interferon regulatory factor-1 gene expression in FRTL-5 rat thyroid cells.

Mori K, Yoshida K, Tani J, Nakagawa Y, Hoshikawa S, Ito S.

Mol Cell Endocrinol. 2001 Nov 26;184(1-2):77-86.

PMID:
11694343
17.

Innate cytokine responses in porcine macrophage populations: evidence for differential recognition of double-stranded RNA.

Loving CL, Brockmeier SL, Ma W, Richt JA, Sacco RE.

J Immunol. 2006 Dec 15;177(12):8432-9.

18.

A synthetic double-stranded RNA, poly I:C, induces a rapid apoptosis of human CD34(+) cells.

Liu J, Guo YM, Hirokawa M, Iwamoto K, Ubukawa K, Michishita Y, Fujishima N, Tagawa H, Takahashi N, Xiao W, Yamashita J, Ohteki T, Sawada K.

Exp Hematol. 2012 Apr;40(4):330-41. doi: 10.1016/j.exphem.2011.12.002. Epub 2011 Dec 20.

PMID:
22198151
19.
20.

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

Gautier G, Humbert M, Deauvieau F, Scuiller M, Hiscott J, Bates EE, Trinchieri G, Caux C, Garrone P.

J Exp Med. 2005 May 2;201(9):1435-46. Epub 2005 Apr 25.

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