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Items: 1 to 20 of 137

1.

Plasma levels of complement proteins from the alternative pathway in patients with age-related macular degeneration are independent of Complement Factor H Tyr⁴⁰²His polymorphism.

Silva AS, Teixeira AG, Bavia L, Lin F, Velletri R, Belfort R Jr, Isaac L.

Mol Vis. 2012;18:2288-99. Epub 2012 Aug 30.

PMID:
22969267
2.

Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration.

Loyet KM, Deforge LE, Katschke KJ Jr, Diehl L, Graham RR, Pao L, Sturgeon L, Lewin-Koh SC, Hollyfield JG, van Lookeren Campagne M.

Invest Ophthalmol Vis Sci. 2012 Sep 25;53(10):6628-37.

PMID:
22930722
3.

Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes.

Reynolds R, Hartnett ME, Atkinson JP, Giclas PC, Rosner B, Seddon JM.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5818-27. doi: 10.1167/iovs.09-3928. Epub 2009 Aug 6.

PMID:
19661236
4.

Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration.

Smailhodzic D, Klaver CC, Klevering BJ, Boon CJ, Groenewoud JM, Kirchhof B, Daha MR, den Hollander AI, Hoyng CB.

Ophthalmology. 2012 Feb;119(2):339-46. doi: 10.1016/j.ophtha.2011.07.056. Epub 2011 Nov 30.

PMID:
22133792
5.

Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration.

Despriet DD, Klaver CC, Witteman JC, Bergen AA, Kardys I, de Maat MP, Boekhoorn SS, Vingerling JR, Hofman A, Oostra BA, Uitterlinden AG, Stijnen T, van Duijn CM, de Jong PT.

JAMA. 2006 Jul 19;296(3):301-9.

PMID:
16849663
6.

Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation.

Khandhadia S, Hakobyan S, Heng LZ, Gibson J, Adams DH, Alexander GJ, Gibson JM, Martin KR, Menon G, Nash K, Sivaprasad S, Ennis S, Cree AJ, Morgan BP, Lotery AJ.

Ophthalmology. 2013 Aug;120(8):1612-8. doi: 10.1016/j.ophtha.2013.01.004. Epub 2013 Apr 4.

PMID:
23562165
7.

C-reactive protein levels and complement factor H polymorphism interaction in age-related macular degeneration and its progression.

Robman L, Baird PN, Dimitrov PN, Richardson AJ, Guymer RH.

Ophthalmology. 2010 Oct;117(10):1982-8. doi: 10.1016/j.ophtha.2010.02.003. Epub 2010 Jun 3.

PMID:
20605213
8.

The Functional Effect of Rare Variants in Complement Genes on C3b Degradation in Patients With Age-Related Macular Degeneration.

Geerlings MJ, Kremlitzka M, Bakker B, Nilsson SC, Saksens NT, Lechanteur YT, Pauper M, Corominas J, Fauser S, Hoyng CB, Blom AM, de Jong EK, den Hollander AI.

JAMA Ophthalmol. 2017 Jan 1;135(1):39-46. doi: 10.1001/jamaophthalmol.2016.4604.

PMID:
27918759
9.

Association between polymorphisms of complement pathway genes and age-related macular degeneration in a Chinese population.

Wu L, Tao Q, Chen W, Wang Z, Song Y, Sheng S, Li P, Zhou J.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):170-4. doi: 10.1167/iovs.12-10453.

PMID:
23233260
10.

Systemic complement activation in age-related macular degeneration.

Scholl HP, Charbel Issa P, Walier M, Janzer S, Pollok-Kopp B, Börncke F, Fritsche LG, Chong NV, Fimmers R, Wienker T, Holz FG, Weber BH, Oppermann M.

PLoS One. 2008 Jul 2;3(7):e2593. doi: 10.1371/journal.pone.0002593. Erratum in: PLoS ONE. 2008;3(7). doi: 10.1371/annotation/511a1029-bc43-4510-a4ca-c1db31810acc. PLoS ONE. 2008;3(7). doi: 10.1371/annotation/32b9bc31-ed6d-4d31-9ce0-480407017bad.

PMID:
18596911
11.

CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.

Contreras AV, Zenteno JC, Fernández-López JC, Rodríguez-Corona U, Falfán-Valencia R, Sebastian L, Morales F, Ochoa-Contreras D, Carnevale A, Silva-Zolezzi I.

Mol Vis. 2014 Jan 14;20:105-16. eCollection 2014.

PMID:
24453474
12.

C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration.

Seddon JM, Gensler G, Rosner B.

Ophthalmology. 2010 Aug;117(8):1560-6. doi: 10.1016/j.ophtha.2009.11.020. Epub 2010 Mar 26.

PMID:
20346514
13.

Growth of geographic atrophy on fundus autofluorescence and polymorphisms of CFH, CFB, C3, FHR1-3, and ARMS2 in age-related macular degeneration.

Caire J, Recalde S, Velazquez-Villoria A, Garcia-Garcia L, Reiter N, Anter J, Fernandez-Robredo P, Alfredo García-Layana; Spanish Multicenter Group on AMD.

JAMA Ophthalmol. 2014 May;132(5):528-34.

PMID:
24557084
14.

Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.

Ansari M, McKeigue PM, Skerka C, Hayward C, Rudan I, Vitart V, Polasek O, Armbrecht AM, Yates JR, Vatavuk Z, Bencic G, Kolcic I, Oostra BA, Van Duijn CM, Campbell S, Stanton CM, Huffman J, Shu X, Khan JC, Shahid H, Harding SP, Bishop PN, Deary IJ, Moore AT, Dhillon B, Rudan P, Zipfel PF, Sim RB, Hastie ND, Campbell H, Wright AF.

Hum Mol Genet. 2013 Dec 1;22(23):4857-69. doi: 10.1093/hmg/ddt336. Epub 2013 Jul 19.

PMID:
23873044
15.

Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid.

Johnson PT, Betts KE, Radeke MJ, Hageman GS, Anderson DH, Johnson LV.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17456-61. Epub 2006 Nov 1.

PMID:
17079491
16.

Association study of complement factor H, C2, CFB, and C3 and age-related macular degeneration in a Han Chinese population.

Liu X, Zhao P, Tang S, Lu F, Hu J, Lei C, Yang X, Lin Y, Ma S, Yang J, Zhang D, Shi Y, Li T, Chen Y, Fan Y, Yang Z.

Retina. 2010 Sep;30(8):1177-84. doi: 10.1097/IAE.0b013e3181cea676.

PMID:
20523265
17.

Association of complement factor H Y402H gene polymorphism with different subtypes of exudative age-related macular degeneration.

Wegscheider BJ, Weger M, Renner W, Steinbrugger I, März W, Mossböck G, Temmel W, El-Shabrawi Y, Schmut O, Jahrbacher R, Haas A.

Ophthalmology. 2007 Apr;114(4):738-42.

PMID:
17398321
18.

Complement component C3 and risk of age-related macular degeneration.

Despriet DD, van Duijn CM, Oostra BA, Uitterlinden AG, Hofman A, Wright AF, ten Brink JB, Bakker A, de Jong PT, Vingerling JR, Bergen AA, Klaver CC.

Ophthalmology. 2009 Mar;116(3):474-480.e2. doi: 10.1016/j.ophtha.2008.09.055. Epub 2009 Jan 24.

PMID:
19168221
19.

C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration.

Bhutto IA, Baba T, Merges C, Juriasinghani V, McLeod DS, Lutty GA.

Br J Ophthalmol. 2011 Sep;95(9):1323-30. doi: 10.1136/bjo.2010.199216. Epub 2011 Jun 1.

PMID:
21633121
20.

Association between vitamin D status and age-related macular degeneration by genetic risk.

Millen AE, Meyers KJ, Liu Z, Engelman CD, Wallace RB, LeBlanc ES, Tinker LF, Iyengar SK, Robinson JG, Sarto GE, Mares JA.

JAMA Ophthalmol. 2015 Oct;133(10):1171-9. doi: 10.1001/jamaophthalmol.2015.2715.

PMID:
26312598

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