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Items: 1 to 20 of 104

1.
2.

5-cholesten-3β,25-diol 3-sulfate decreases lipid accumulation in diet-induced nonalcoholic fatty liver disease mouse model.

Xu L, Kim JK, Bai Q, Zhang X, Kakiyama G, Min HK, Sanyal AJ, Pandak WM, Ren S.

Mol Pharmacol. 2013 Mar;83(3):648-58. doi: 10.1124/mol.112.081505.

3.

Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase.

Deng X, Dong Q, Bridges D, Raghow R, Park EA, Elam MB.

Biochim Biophys Acta. 2015 Dec;1851(12):1521-9. doi: 10.1016/j.bbalip.2015.08.007.

PMID:
26327595
4.

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL.

J Clin Invest. 1997 Mar 1;99(5):846-54.

5.

Modulation of hepatic sterol regulatory element-binding protein-1c-mediated gene expression contributes to Salacia oblonga root-elicited improvement of fructose-induced fatty liver in rats.

Liu L, Yang M, Lin X, Li Y, Liu C, Yang Y, Yamahara J, Wang J, Li Y.

J Ethnopharmacol. 2013 Dec 12;150(3):1045-52. doi: 10.1016/j.jep.2013.10.020.

PMID:
24157375
6.

Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass.

Knebel B, Haas J, Hartwig S, Jacob S, Köllmer C, Nitzgen U, Muller-Wieland D, Kotzka J.

PLoS One. 2012;7(2):e31812. doi: 10.1371/journal.pone.0031812.

8.

Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins.

Moon YA, Shah NA, Mohapatra S, Warrington JA, Horton JD.

J Biol Chem. 2001 Nov 30;276(48):45358-66.

9.

Enhancement in liver SREBP-1c/PPAR-alpha ratio and steatosis in obese patients: correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion.

Pettinelli P, Del Pozo T, Araya J, Rodrigo R, Araya AV, Smok G, Csendes A, Gutierrez L, Rojas J, Korn O, Maluenda F, Diaz JC, Rencoret G, Braghetto I, Castillo J, Poniachik J, Videla LA.

Biochim Biophys Acta. 2009 Nov;1792(11):1080-6. doi: 10.1016/j.bbadis.2009.08.015.

10.
11.

Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2.

Im SS, Hammond LE, Yousef L, Nugas-Selby C, Shin DJ, Seo YK, Fong LG, Young SG, Osborne TF.

Mol Cell Biol. 2009 Sep;29(17):4864-72. doi: 10.1128/MCB.00553-09. Erratum in: Mol Cell Biol. 2009 Nov;29(21):5974.

12.

Glucose induces de novo lipogenesis in rat muscle satellite cells through a sterol-regulatory-element-binding-protein-1c-dependent pathway.

Guillet-Deniau I, Pichard AL, Koné A, Esnous C, Nieruchalski M, Girard J, Prip-Buus C.

J Cell Sci. 2004 Apr 15;117(Pt 10):1937-44.

13.

Sterol regulatory element-binding protein-1c and pancreatic beta-cell dysfunction.

Shimano H, Amemiya-Kudo M, Takahashi A, Kato T, Ishikawa M, Yamada N.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:133-9.

PMID:
17919187
14.

Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis.

Shearn CT, Smathers RL, Jiang H, Orlicky DJ, Maclean KN, Petersen DR.

J Nutr Biochem. 2013 Aug;24(8):1436-45. doi: 10.1016/j.jnutbio.2012.12.002.

15.

TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c).

Endo M, Masaki T, Seike M, Yoshimatsu H.

Exp Biol Med (Maywood). 2007 May;232(5):614-21.

PMID:
17463157
16.

Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway.

Wu W, Tang S, Shi J, Yin W, Cao S, Bu R, Zhu D, Bi Y.

Int J Mol Med. 2015 Jun;35(6):1734-40. doi: 10.3892/ijmm.2015.2187.

PMID:
25891779
17.

Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcription.

Bi Y, Wu W, Shi J, Liang H, Yin W, Chen Y, Tang S, Cao S, Cai M, Shen S, Gao Q, Weng J, Zhu D.

Diabetologia. 2014 Mar;57(3):592-602. doi: 10.1007/s00125-013-3136-1.

PMID:
24362725
18.

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.

Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H.

J Lipid Res. 2010 Jul;51(7):1859-70. doi: 10.1194/jlr.M004234.

19.

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression.

Dentin R, Pégorier JP, Benhamed F, Foufelle F, Ferré P, Fauveau V, Magnuson MA, Girard J, Postic C.

J Biol Chem. 2004 May 7;279(19):20314-26.

20.

SREBP-1c overexpression induces triglycerides accumulation through increasing lipid synthesis and decreasing lipid oxidation and VLDL assembly in bovine hepatocytes.

Li X, Li Y, Yang W, Xiao C, Fu S, Deng Q, Ding H, Wang Z, Liu G, Li X.

J Steroid Biochem Mol Biol. 2014 Sep;143:174-82. doi: 10.1016/j.jsbmb.2014.02.009.

PMID:
24565561
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