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Involvement of the WNT and FGF signaling pathways in non-isolated anorectal malformations: sequencing analysis of WNT3A, WNT5A, WNT11, DACT1, FGF10, FGFR2 and the T gene.

Draaken M, Prins W, Zeidler C, Hilger A, Mughal SS, Latus J, Boemers TM, Schmidt D, Schmiedeke E, Spychalski N, Bartels E, Nöthen MM, Reutter H, Ludwig M.

Int J Mol Med. 2012 Dec;30(6):1459-64. doi: 10.3892/ijmm.2012.1124. Epub 2012 Sep 7.


Reduced Fgf10/Fgfr2 and androgen receptor (AR) in anorectal malformations male rats induced by di-n-butyl phthalate (DBP): A study on the local and systemic toxicology of DBP.

Jiang JT, Xu HL, Zhu YP, Wood K, Li EH, Sun WL, Yuan Q, Xu DL, Liu ZH, Zhao W, Xia SJ.

Toxicology. 2015 Dec 2;338:77-85. doi: 10.1016/j.tox.2015.10.006. Epub 2015 Oct 26.


Reduced Wnt3a expression correlates with poor development of the hindgut in rats with anorectal malformations.

Ren X, Mi J, Jia H, Gao H, Bai Y, Wang W.

Exp Mol Pathol. 2015 Aug;99(1):81-5. doi: 10.1016/j.yexmp.2015.05.008. Epub 2015 May 27.


Genotype and haplotype analysis of WNT genes in non-syndromic cleft lip with or without cleft palate.

Mostowska A, Hozyasz KK, Biedziak B, Wojcicki P, Lianeri M, Jagodzinski PP.

Eur J Oral Sci. 2012 Feb;120(1):1-8. doi: 10.1111/j.1600-0722.2011.00938.x.


Homeobox, Wnt, and Fibroblast Growth Factor Signaling is Augmented During Alveogenesis in Mice Lacking Superoxide Dismutase 3, Extracellular.

Thimraj TA, Birru RL, Mitra A, Schulz H, Leikauf GD, Ganguly K.

Lung. 2017 Apr;195(2):263-270. doi: 10.1007/s00408-017-9980-x. Epub 2017 Feb 20.


Genome-wide copy number variation study in anorectal malformations.

Wong EH, Cui L, Ng CL, Tang CS, Liu XL, So MT, Yip BH, Cheng G, Zhang R, Tang WK, Yang W, Lau YL, Baum L, Kwan P, Sun LD, Zuo XB, Ren YQ, Yin XY, Miao XP, Liu J, Lui VC, Ngan ES, Yuan ZW, Zhang SW, Xia J, Wang H, Sun XB, Wang R, Chang T, Chan IH, Chung PH, Zhang XJ, Wong KK, Cherny SS, Sham PC, Tam PK, Garcia-Barcelo MM.

Hum Mol Genet. 2013 Feb 1;22(3):621-31. doi: 10.1093/hmg/dds451. Epub 2012 Oct 29.


Spatiotemporal expression of Wnt5a during the development of the striated muscle complex in rats with anorectal malformations.

Mi J, Chen D, Ren X, Jia H, Gao H, Wang W.

Int J Clin Exp Pathol. 2014 Apr 15;7(5):1997-2005. eCollection 2014.


Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations.

Ng RC, Matsumaru D, Ho AS, Garcia-Barceló MM, Yuan ZW, Smith D, Kodjabachian L, Tam PK, Yamada G, Lui VC.

Cell Death Differ. 2014 Jun;21(6):978-89. doi: 10.1038/cdd.2014.20. Epub 2014 Mar 14.


Investigation of FGF10 as a candidate gene in patients with anorectal malformations and exstrophy of the cloaca.

Krüger V, Khoshvaghti M, Reutter H, Vogt H, Boemers TM, Ludwig M.

Pediatr Surg Int. 2008 Aug;24(8):893-7. doi: 10.1007/s00383-008-2193-x. Epub 2008 Jun 28.


Characterization of a Wnt-binding site of the WIF-domain of Wnt inhibitory factor-1.

Bányai L, Kerekes K, Patthy L.

FEBS Lett. 2012 Sep 21;586(19):3122-6. doi: 10.1016/j.febslet.2012.07.072. Epub 2012 Aug 8.


Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice.

Marguerie A, Bajolle F, Zaffran S, Brown NA, Dickson C, Buckingham ME, Kelly RG.

Cardiovasc Res. 2006 Jul 1;71(1):50-60. Epub 2006 Apr 4.


Effect of Wnt3a on keratinocytes utilizing in vitro and bioinformatics analysis.

Nam JS, Chakraborty C, Sharma AR, Her Y, Bae KJ, Sharma G, Doss GP, Lee SS, Hong MS, Song DK.

Int J Mol Sci. 2014 Mar 28;15(4):5472-95. doi: 10.3390/ijms15045472.


Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations.

Miyagawa S, Harada M, Matsumaru D, Tanaka K, Inoue C, Nakahara C, Haraguchi R, Matsushita S, Suzuki K, Nakagata N, Ng RC, Akita K, Lui VC, Yamada G.

Cell Death Differ. 2014 Jun;21(6):990-7. doi: 10.1038/cdd.2014.21. Epub 2014 Mar 14.


Wnt5a knock-out mouse as a new model of anorectal malformation.

Tai CC, Sala FG, Ford HR, Wang KS, Li C, Minoo P, Grikscheit TC, Bellusci S.

J Surg Res. 2009 Oct;156(2):278-82. doi: 10.1016/j.jss.2009.03.087. Epub 2009 May 8.


Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades.

Katoh M, Katoh M.

Cancer Biol Ther. 2006 Sep;5(9):1059-64. Epub 2006 Sep 4. Review.


Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10.

Huijts PE, van Dongen M, de Goeij MC, van Moolenbroek AJ, Blanken F, Vreeswijk MP, de Kruijf EM, Mesker WE, van Zwet EW, Tollenaar RA, Smit VT, van Asperen CJ, Devilee P.

Breast Cancer Res. 2011 Jul 18;13(4):R72. doi: 10.1186/bcr2917.


Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT.

Bisson JA, Mills B, Paul Helt JC, Zwaka TP, Cohen ED.

Dev Biol. 2015 Feb 1;398(1):80-96. doi: 10.1016/j.ydbio.2014.11.015. Epub 2014 Dec 5.


Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes-Brocks Syndrome.

Webb BD, Metikala S, Wheeler PG, Sherpa MD, Houten SM, Horb ME, Schadt EE.

Hum Mutat. 2017 Apr;38(4):373-377. doi: 10.1002/humu.23171. Epub 2017 Feb 2.


Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.

Agarwal P, Wylie JN, Galceran J, Arkhitko O, Li C, Deng C, Grosschedl R, Bruneau BG.

Development. 2003 Feb;130(3):623-33.


Up-regulation of fibroblast growth factor (FGF) 9 expression and FGF-WNT/β-catenin signaling in laser-induced wound healing.

Zheng Z, Kang HY, Lee S, Kang SW, Goo B, Cho SB.

Wound Repair Regen. 2014 Sep-Oct;22(5):660-5. doi: 10.1111/wrr.12212.


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