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Items: 1 to 20 of 65

1.

BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9.

Qin Y, Xu J, Aysola K, Oprea G, Reddy A, Matthews R, Okoli J, Cantor A, Grizzle WE, Partridge EE, Reddy ES, Landen C, Rao VN.

Am J Cancer Res. 2012;2(5):540-8. Epub 2012 Aug 20.

2.

Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins.

Qin Y, Xu J, Aysola K, Begum N, Reddy V, Chai Y, Grizzle WE, Partridge EE, Reddy ES, Rao VN.

J Cell Physiol. 2011 Dec;226(12):3355-67. doi: 10.1002/jcp.22695.

3.

A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells.

Xu J, Agyemang S, Qin Y, Aysola K, Giles M, Oprea G, O'Regan RM, Partridge EE, Harris-Hooker S, Rice VM, Reddy ES, Rao VN.

Enliven Chall Cancer Detect Ther. 2014;1(1). pii: 004.

4.

BRCA1 Mutation Leads to Deregulated Ubc9 Levels which Triggers Proliferation and Migration of Patient-Derived High Grade Serous Ovarian Cancer and Triple Negative Breast Cancer Cells.

Xu J, Footman A, Qin Y, Aysola K, Black S, Reddy V, Singh K, Grizzle W, You S, Moellering D, Reddy ES, Fu Y, Rao VN.

Int J Chronic Dis Ther. 2016;2(3):31-38. Epub 2016 Jun 23.

7.

Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites.

Desai A, Xu J, Aysola K, Akinbobuyi O, White M, Reddy VE, Okoli J, Clark C, Partridge EE, Childs E, Beech DJ, Rice MV, Reddy E, Rao VN.

J Gynecol Res. 2015;1(1). pii: 103. Epub 2015 Apr 24.

8.

Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteins.

Maniccia AW, Lewis C, Begum N, Xu J, Cui J, Chipitsyna G, Aysola K, Reddy V, Bhat G, Fujimura Y, Henderson B, Reddy ES, Rao VN.

J Cell Physiol. 2009 Jun;219(3):634-41. doi: 10.1002/jcp.21708.

9.

BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers.

Yuli C, Shao N, Rao R, Aysola P, Reddy V, Oprea-llies G, Lee L, Okoli J, Partridge E, Reddy ES, Rao VN.

Oncogene. 2007 Sep 6;26(41):6031-7. Epub 2007 Mar 26.

PMID:
17384678
10.

c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells.

Chai Y, Chipitsyna G, Cui J, Liao B, Liu S, Aysola K, Yezdani M, Reddy ES, Rao VN.

Oncogene. 2001 Mar 15;20(11):1357-67.

11.
12.

Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women.

Agboola AO, Musa AA, Ayoade BA, Banjo AA, Anunobi CC, Deji-Agboola AM, Rakha EA, Nolan C, Ellis IO, Green AR.

Pathol Res Pract. 2014 Jan;210(1):10-7. doi: 10.1016/j.prp.2013.09.011. Epub 2013 Oct 8.

PMID:
24176171
13.

Ovarian Cancer Gene Therapy with BRCA1-An Overview.

Obermiller PS, Holt JT.

Methods Mol Med. 2000;35:593-607. doi: 10.1385/1-59259-086-1:593.

PMID:
21390833
14.

A role for Ubc9 in tumorigenesis.

Mo YY, Yu Y, Theodosiou E, Ee PL, Beck WT.

Oncogene. 2005 Apr 14;24(16):2677-83.

PMID:
15735760
15.

Regulation of bcl-2 expression by Ubc9.

Lu Z, Wu H, Mo YY.

Exp Cell Res. 2006 Jun 10;312(10):1865-75. Epub 2006 Mar 29.

PMID:
16566921
16.
17.

The p53 mutational spectrum associated with BRCA1 mutant ovarian cancer.

Buller RE, Lallas TA, Shahin MS, Sood AK, Hatterman-Zogg M, Anderson B, Sorosky JI, Kirby PA.

Clin Cancer Res. 2001 Apr;7(4):831-8.

18.

Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer.

Hong H, Yen HY, Brockmeyer A, Liu Y, Chodankar R, Pike MC, Stanczyk FZ, Maxson R, Dubeau L.

Cancer Res. 2010 Jan 1;70(1):221-8. doi: 10.1158/0008-5472.CAN-09-3232. Epub 2009 Dec 22.

19.

Characterization of amino acid residues within the N-terminal region of Ubc9 that play a role in Ubc9 nuclear localization.

Sekhri P, Tao T, Kaplan F, Zhang XD.

Biochem Biophys Res Commun. 2015 Feb 27;458(1):128-33. doi: 10.1016/j.bbrc.2015.01.081. Epub 2015 Jan 27.

PMID:
25637535
20.

Enhanced SUMOylation of proteins containing a SUMO-interacting motif by SUMO-Ubc9 fusion.

Kim ET, Kim KK, Matunis MJ, Ahn JH.

Biochem Biophys Res Commun. 2009 Oct 9;388(1):41-5. doi: 10.1016/j.bbrc.2009.07.103. Epub 2009 Jul 25.

PMID:
19635459

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