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TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells.

Flamant L, Roegiers E, Pierre M, Hayez A, Sterpin C, De Backer O, Arnould T, Poumay Y, Michiels C.

BMC Cancer. 2012 Sep 6;12:391. doi: 10.1186/1471-2407-12-391.


miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1.

Rebucci M, Sermeus A, Leonard E, Delaive E, Dieu M, Fransolet M, Arnould T, Michiels C.

Mol Cancer. 2015 Apr 8;14:79. doi: 10.1186/s12943-015-0349-6.


Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation.

Notte A, Ninane N, Arnould T, Michiels C.

Cell Death Dis. 2013 May 16;4:e638. doi: 10.1038/cddis.2013.167.


BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway.

Cosse JP, Rommelaere G, Ninane N, Arnould T, Michiels C.

Biochem Pharmacol. 2010 Oct 15;80(8):1160-9. doi: 10.1016/j.bcp.2010.07.009. Epub 2010 Jul 15.


Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis.

Notte A, Rebucci M, Fransolet M, Roegiers E, Genin M, Tellier C, Watillon K, Fattaccioli A, Arnould T, Michiels C.

Int J Biochem Cell Biol. 2015 May;62:1-14. doi: 10.1016/j.biocel.2015.02.010. Epub 2015 Feb 24.


[Sensitivity to chemotherapeutic drugs of polyploid tumor cells induced by a spindle poison nocodazole].

Hao J, Yuan BB, Xu YF, Yu J, Liu GY, Wang DH.

Zhonghua Zhong Liu Za Zhi. 2012 Jun;34(6):419-24. doi: 10. 3760/cma.j.issn.0253-3766.2012.06.005. Chinese.


Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity.

Sermeus A, Cosse JP, Crespin M, Mainfroid V, de Longueville F, Ninane N, Raes M, Remacle J, Michiels C.

Mol Cancer. 2008 Mar 26;7:27. doi: 10.1186/1476-4598-7-27.


MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.

Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M.

J Biol Chem. 2010 Jul 9;285(28):21496-507. doi: 10.1074/jbc.M109.083337. Epub 2010 May 11.


Long interspersed nuclear element ORF-1 protein promotes proliferation and resistance to chemotherapy in hepatocellular carcinoma.

Feng F, Lu YY, Zhang F, Gao XD, Zhang CF, Meredith A, Xu ZX, Yang YT, Chang XJ, Wang H, Qu JH, Zeng Z, Yang JL, Wang CP, Zhu YF, Cui JJ, Yang YP.

World J Gastroenterol. 2013 Feb 21;19(7):1068-78. doi: 10.3748/wjg.v19.i7.1068.


MiRNA153 Reduces Effects of Chemotherapeutic Agents or Small Molecular Kinase Inhibitor in HCC Cells.

Chen Y, Feng F, Gao X, Wang C, Sun H, Zhang C, Zeng Z, Lu Y, An L, Qu J, Wang F, Yang Y.

Curr Cancer Drug Targets. 2015;15(3):176-87.


Differential effects of hypoxia on etoposide-induced apoptosis according to the cancer cell lines.

Cosse JP, Sermeus A, Vannuvel K, Ninane N, Raes M, Michiels C.

Mol Cancer. 2007 Sep 26;6:61.


ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway.

Wang XJ, Feng CW, Li M.

Mol Cell Biochem. 2013 Aug;380(1-2):57-66. doi: 10.1007/s11010-013-1657-z. Epub 2013 Apr 28.


[Reversal effect of MDR1 and MDR3 gene silencing on resistance of A2780/taxol cells to paclitaxel].

Xiao L, Gao R, Lu S, Lu MS, Liang ML, Ren LR, Wang ZH.

Zhonghua Fu Chan Ke Za Zhi. 2007 Jun;42(6):412-6. Chinese.


Hypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell types.

Sermeus A, Genin M, Maincent A, Fransolet M, Notte A, Leclere L, Riquier H, Arnould T, Michiels C.

PLoS One. 2012;7(11):e47519. doi: 10.1371/journal.pone.0047519. Epub 2012 Nov 5.


miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer.

Hu Y, Xu K, Yag├╝e E.

Breast Cancer Res Treat. 2015 Jun;151(2):269-80. doi: 10.1007/s10549-015-3372-9. Epub 2015 Apr 22.


Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library.

Zhao L, Pan Y, Gang Y, Wang H, Jin H, Tie J, Xia L, Zhang Y, He L, Yao L, Qiao T, Li T, Liu Z, Fan D.

J Biol Chem. 2009 Sep 25;284(39):26273-85. doi: 10.1074/jbc.M109.028068. Epub 2009 Jul 28.


Knockdown of UbcH10 enhances the chemosensitivity of dual drug resistant breast cancer cells to epirubicin and docetaxel.

Wang C, Pan YH, Shan M, Xu M, Bao JL, Zhao LM.

Int J Mol Sci. 2015 Mar 2;16(3):4698-712. doi: 10.3390/ijms16034698.


Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells.

Ajabnoor GM, Crook T, Coley HM.

Cell Death Dis. 2012 Jan 26;3:e260. doi: 10.1038/cddis.2011.139.

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