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Items: 1 to 20 of 535

1.

Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.

Dibaj P, Zschüntzsch J, Steffens H, Scheffel J, Göricke B, Weishaupt JH, Le Meur K, Kirchhoff F, Hanisch UK, Schomburg ED, Neusch C.

PLoS One. 2012;7(8):e43963. doi: 10.1371/journal.pone.0043963. Epub 2012 Aug 27.

2.

Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase.

Lewis KE, Rasmussen AL, Bennett W, King A, West AK, Chung RS, Chuah MI.

J Neuroinflammation. 2014 Mar 23;11:55. doi: 10.1186/1742-2094-11-55.

3.

Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.

Apolloni S, Amadio S, Montilli C, Volonté C, D'Ambrosi N.

Hum Mol Genet. 2013 Oct 15;22(20):4102-16. doi: 10.1093/hmg/ddt259. Epub 2013 Jun 4.

PMID:
23736299
4.

Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.

Apolloni S, Fabbrizio P, Amadio S, Volonté C.

J Neuroinflammation. 2016 Aug 22;13(1):191. doi: 10.1186/s12974-016-0658-8.

5.

Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Milanese M, Giribaldi F, Melone M, Bonifacino T, Musante I, Carminati E, Rossi PI, Vergani L, Voci A, Conti F, Puliti A, Bonanno G.

Neurobiol Dis. 2014 Apr;64:48-59. doi: 10.1016/j.nbd.2013.11.006. Epub 2013 Dec 19.

6.

Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.

Fellner A, Barhum Y, Angel A, Perets N, Steiner I, Offen D, Lev N.

Int J Mol Sci. 2017 Aug 1;18(8). pii: E1666. doi: 10.3390/ijms18081666.

7.

Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP.

J Neurosci. 2008 Oct 8;28(41):10234-44. doi: 10.1523/JNEUROSCI.3494-08.2008.

8.

Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis.

Apolloni S, Amadio S, Parisi C, Matteucci A, Potenza RL, Armida M, Popoli P, D'Ambrosi N, Volonté C.

Dis Model Mech. 2014 Sep;7(9):1101-9. doi: 10.1242/dmm.017038. Epub 2014 Jul 18.

9.

In Vivo imaging reveals distinct inflammatory activity of CNS microglia versus PNS macrophages in a mouse model for ALS.

Dibaj P, Steffens H, Zschüntzsch J, Nadrigny F, Schomburg ED, Kirchhoff F, Neusch C.

PLoS One. 2011 Mar 18;6(3):e17910. doi: 10.1371/journal.pone.0017910.

10.

Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models.

Audet JN, Soucy G, Julien JP.

Neuroscience. 2012 May 3;209:136-43. doi: 10.1016/j.neuroscience.2011.12.047. Epub 2012 Jan 3.

PMID:
22230045
11.

In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

Bonifacino T, Cattaneo L, Gallia E, Puliti A, Melone M, Provenzano F, Bossi S, Musante I, Usai C, Conti F, Bonanno G, Milanese M.

Neuropharmacology. 2017 Sep 1;123:433-445. doi: 10.1016/j.neuropharm.2017.06.020. Epub 2017 Jun 21.

PMID:
28645622
12.

PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Ringer C, Büning LS, Schäfer MK, Eiden LE, Weihe E, Schütz B.

Neurobiol Dis. 2013 Jun;54:32-42. doi: 10.1016/j.nbd.2013.02.010. Epub 2013 Mar 4.

13.

System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.

Mesci P, Zaïdi S, Lobsiger CS, Millecamps S, Escartin C, Seilhean D, Sato H, Mallat M, Boillée S.

Brain. 2015 Jan;138(Pt 1):53-68. doi: 10.1093/brain/awu312. Epub 2014 Nov 10.

14.

Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice.

Sheean RK, Weston RH, Perera ND, D'Amico A, Nutt SL, Turner BJ.

J Neuroinflammation. 2015 Feb 27;12:40. doi: 10.1186/s12974-015-0254-3.

15.

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.

Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C.

Brain. 2013 Nov;136(Pt 11):3305-32. doi: 10.1093/brain/awt250. Epub 2013 Sep 24.

PMID:
24065725
16.

Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Novoselov SS, Mustill WJ, Gray AL, Dick JR, Kanuga N, Kalmar B, Greensmith L, Cheetham ME.

PLoS One. 2013 Aug 30;8(8):e73944. doi: 10.1371/journal.pone.0073944. eCollection 2013.

17.

Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse.

Yang WW, Sidman RL, Taksir TV, Treleaven CM, Fidler JA, Cheng SH, Dodge JC, Shihabuddin LS.

Exp Neurol. 2011 Feb;227(2):287-95. doi: 10.1016/j.expneurol.2010.11.019. Epub 2010 Dec 9.

PMID:
21145892
18.

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.

Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH.

Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):16021-6. Epub 2006 Oct 16.

19.

Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.

Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R.

J Neurosci. 2008 Apr 16;28(16):4115-22. doi: 10.1523/JNEUROSCI.5308-07.2008.

20.

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