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Items: 1 to 20 of 149

1.

High-throughput screening of stem cell therapy for globoid cell leukodystrophy using automated neurophenotyping of twitcher mice.

Scruggs BA, Bowles AC, Zhang X, Semon JA, Kyzar EJ, Myers L, Kalueff AV, Bunnell BA.

Behav Brain Res. 2013 Jan 1;236(1):35-47. doi: 10.1016/j.bbr.2012.08.020. Epub 2012 Aug 20.

2.

Multipotent stromal cells alleviate inflammation, neuropathology, and symptoms associated with globoid cell leukodystrophy in the twitcher mouse.

Scruggs BA, Zhang X, Bowles AC, Gold PA, Semon JA, Fisher-Perkins JM, Zhang S, Bonvillain RW, Myers L, Li SC, Kalueff AV, Bunnell BA.

Stem Cells. 2013 Aug;31(8):1523-34. doi: 10.1002/stem.1397.

4.

Mesenchymal lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's disease.

Ripoll CB, Flaat M, Klopf-Eiermann J, Fisher-Perkins JM, Trygg CB, Scruggs BA, McCants ML, Leonard HP, Lin AF, Zhang S, Eagle ME, Alvarez X, Li YT, Li SC, Gimble JM, Bunnell BA.

Stem Cells. 2011 Jan;29(1):67-77. doi: 10.1002/stem.555.

5.

TNF-receptor 1 deficiency fails to alter the clinical and pathological course in mice with globoid cell leukodystrophy (twitcher mice) but affords protection following LPS challenge.

Pedchenko TV, Bronshteyn IG, LeVine SM.

J Neuroimmunol. 2000 Oct 2;110(1-2):186-94. Erratum in: J Neuroimmunol 2001 Jun 1;116(2):242.

PMID:
11024549
6.
7.

Mitigation of cerebellar neuropathy in globoid cell leukodystrophy mice by AAV-mediated gene therapy.

Lin DS, Hsiao CD, Lee AY, Ho CS, Liu HL, Wang TJ, Jian YR, Hsu JC, Huang ZD, Lee TH, Chiang MF.

Gene. 2015 Oct 15;571(1):81-90. doi: 10.1016/j.gene.2015.06.049. Epub 2015 Jun 23.

PMID:
26115766
8.

Transplantation of mouse embryonic stem cell-derived oligodendrocytes in the murine model of globoid cell leukodystrophy.

Kuai XL, Ni RZ, Zhou GX, Mao ZB, Zhang JF, Yi N, Liu ZX, Shao N, Ni WK, Wang ZW.

Stem Cell Res Ther. 2015 Mar 14;6:30. doi: 10.1186/s13287-015-0024-2.

9.

Bone marrow transplantation increases efficacy of central nervous system-directed enzyme replacement therapy in the murine model of globoid cell leukodystrophy.

Qin EY, Hawkins-Salsbury JA, Jiang X, Reddy AS, Farber NB, Ory DS, Sands MS.

Mol Genet Metab. 2012 Sep;107(1-2):186-96. doi: 10.1016/j.ymgme.2012.05.021. Epub 2012 Jun 1.

11.

Prolonged survival and remyelination after hematopoietic cell transplantation in the twitcher mouse.

Yeager AM, Brennan S, Tiffany C, Moser HW, Santos GW.

Science. 1984 Sep 7;225(4666):1052-4.

PMID:
6382609
12.

L-cycloserine slows the clinical and pathological course in mice with globoid cell leukodystrophy (twitcher mice).

LeVine SM, Pedchenko TV, Bronshteyn IG, Pinson DM.

J Neurosci Res. 2000 Apr 15;60(2):231-6.

PMID:
10740228
13.
14.

CNS-targeted AAV5 gene transfer results in global dispersal of vector and prevention of morphological and function deterioration in CNS of globoid cell leukodystrophy mouse model.

Lin DS, Hsiao CD, Liau I, Lin SP, Chiang MF, Chuang CK, Wang TJ, Wu TY, Jian YR, Huang SF, Liu HL.

Mol Genet Metab. 2011 Aug;103(4):367-77. doi: 10.1016/j.ymgme.2011.05.005. Epub 2011 May 12.

PMID:
21620749
15.

Donor-derived cells in the central nervous system of twitcher mice after bone marrow transplantation.

Hoogerbrugge PM, Suzuki K, Suzuki K, Poorthuis BJ, Kobayashi T, Wagemaker G, van Bekkum DW.

Science. 1988 Feb 26;239(4843):1035-8.

PMID:
3278379
16.

IL-6 deficiency causes enhanced pathology in Twitcher (globoid cell leukodystrophy) mice.

Pedchenko TV, LeVine SM.

Exp Neurol. 1999 Aug;158(2):459-68.

PMID:
10415153
17.

Systemic delivery of bone marrow-derived mesenchymal stromal cells diminishes neuropathology in a mouse model of Krabbe's disease.

Miranda CO, Teixeira CA, Liz MA, Sousa VF, Franquinho F, Forte G, Di Nardo P, Pinto-Do-Ó P, Sousa MM.

Stem Cells. 2011 Nov;29(11):1738-51. doi: 10.1002/stem.724.

18.
19.

Significant correction of pathology in brains of twitcher mice following injection of genetically modified mouse neural progenitor cells.

Strazza M, Luddi A, Carbone M, Rafi MA, Costantino-Ceccarini E, Wenger DA.

Mol Genet Metab. 2009 May;97(1):27-34. doi: 10.1016/j.ymgme.2009.01.005. Epub 2009 Feb 12.

PMID:
19217332
20.

Genetic background markedly influences vulnerability of the hippocampal neuronal organization in the "twitcher" mouse model of globoid cell leukodystrophy.

Tominaga K, Matsuda J, Kido M, Naito E, Yokota I, Toida K, Ishimura K, Suzuki K, Kuroda Y.

J Neurosci Res. 2004 Aug 15;77(4):507-16.

PMID:
15264220

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