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Gender related differences in kidney injury induced by mercury.

Hazelhoff MH, Bulacio RP, Torres AM.

Int J Mol Sci. 2012;13(8):10523-36. doi: 10.3390/ijms130810523. Epub 2012 Aug 22.


Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride.

Di Giusto G, Anzai N, Ruiz ML, Endou H, Torres AM.

Arch Toxicol. 2009 Oct;83(10):887-97. doi: 10.1007/s00204-009-0445-8. Epub 2009 Jun 17.


Altered Renal Expression of Relevant Clinical Drug Transporters in Different Models of Acute Uremia in Rats. Role of Urea Levels.

Brandoni A, Torres AM.

Cell Physiol Biochem. 2015;36(3):907-16. doi: 10.1159/000430265. Epub 2015 Jun 9.


Organic anion transporter 5 renal expression and urinary excretion in rats exposed to mercuric chloride: a potential biomarker of mercury-induced nephropathy.

Di Giusto G, Torres AM.

Arch Toxicol. 2010 Oct;84(10):741-9. doi: 10.1007/s00204-010-0541-9. Epub 2010 Apr 17.


Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure.

Komazawa H, Yamaguchi H, Hidaka K, Ogura J, Kobayashi M, Iseki K.

J Pharm Sci. 2013 Mar;102(3):1086-94. doi: 10.1002/jps.23433. Epub 2012 Dec 29.


JBP485 improves gentamicin-induced acute renal failure by regulating the expression and function of Oat1 and Oat3 in rats.

Guo X, Meng Q, Liu Q, Wang C, Sun H, Peng J, Ma X, Kaku T, Liu K.

Toxicol Appl Pharmacol. 2013 Sep 1;271(2):285-95. doi: 10.1016/j.taap.2013.04.029. Epub 2013 May 23.


Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction.

Villar SR, Brandoni A, Anzai N, Endou H, Torres AM.

Kidney Int. 2005 Dec;68(6):2704-13.


Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury.

Torres AM, Dnyanmote AV, Bush KT, Wu W, Nigam SK.

J Biol Chem. 2011 Jul 29;286(30):26391-5. doi: 10.1074/jbc.M111.249292. Epub 2011 Jun 7.


Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.

Schneider R, Sauvant C, Betz B, Otremba M, Fischer D, Holzinger H, Wanner C, Galle J, Gekle M.

Am J Physiol Renal Physiol. 2007 May;292(5):F1599-605. Epub 2007 Jan 23.


Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats.

Liu T, Meng Q, Wang C, Liu Q, Guo X, Sun H, Peng J, Ma X, Kaku T, Liu K.

Toxicol Appl Pharmacol. 2012 Nov 1;264(3):423-30. doi: 10.1016/j.taap.2012.08.019. Epub 2012 Aug 27.


Oat1/3 restoration protects against renal damage after ischemic AKI.

Schneider R, Meusel M, Betz B, Held C, Möller-Ehrlich K, Büttner-Herold M, Wanner C, Gekle M, Sauvant C.

Am J Physiol Renal Physiol. 2015 Feb 1;308(3):F198-208. doi: 10.1152/ajprenal.00160.2014. Epub 2014 Nov 12.


Inhibitory effect of JBP485 on renal excretion of acyclovir by the inhibition of OAT1 and OAT3.

Ye J, Liu Q, Wang C, Meng Q, Peng J, Sun H, Kaku T, Liu K.

Eur J Pharm Sci. 2012 Sep 29;47(2):341-6. doi: 10.1016/j.ejps.2012.06.004. Epub 2012 Jun 21.


Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition.

Ljubojevic M, Herak-Kramberger CM, Hagos Y, Bahn A, Endou H, Burckhardt G, Sabolic I.

Am J Physiol Renal Physiol. 2004 Jul;287(1):F124-38. Epub 2004 Mar 9.


Effect of lycopene against cisplatin-induced acute renal injury in rats: organic anion and cation transporters evaluation.

Erman F, Tuzcu M, Orhan C, Sahin N, Sahin K.

Biol Trace Elem Res. 2014 Apr;158(1):90-5. doi: 10.1007/s12011-014-9914-x. Epub 2014 Feb 16.


A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.

Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T.

Am J Physiol Renal Physiol. 2012 May 15;302(10):F1293-9. doi: 10.1152/ajprenal.00013.2012. Epub 2012 Feb 15.


Renal expression and function of oat1 and oat3 in rats with vascular calcification.

Bulacio R, Hazelhoff MH, Torres AM.

Pharmacology. 2012;90(1-2):66-77. doi: 10.1159/000339448. Epub 2012 Jun 29.


Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3).

Astorga B, Wunz TM, Morales M, Wright SH, Pelis RM.

Am J Physiol Renal Physiol. 2011 Aug;301(2):F378-86. doi: 10.1152/ajprenal.00735.2010. Epub 2011 May 4.


Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats.

Liu T, Guo X, Meng Q, Wang C, Liu Q, Sun H, Ma X, Kaku T, Liu K.

Peptides. 2012 Jul;36(1):78-85. doi: 10.1016/j.peptides.2012.04.003. Epub 2012 Apr 11.


Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome.

Schneider R, Meusel M, Renker S, Bauer C, Holzinger H, Roeder M, Wanner C, Gekle M, Sauvant C.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1614-21. doi: 10.1152/ajprenal.00268.2009. Epub 2009 Sep 30.


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