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Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer.

Xia J, Li Y, Yang Q, Mei C, Chen Z, Bao B, Ahmad A, Miele L, Sarkar FH, Wang Z.

Int J Mol Sci. 2012;13(8):9627-41. doi: 10.3390/ijms13089627. Epub 2012 Aug 2. Erratum in: Int J Mol Sci. 2014;15(8):14907-8.


Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-κB-Mediated Mechanism.

Ghaffari SH, Yousefi M, Dizaji MZ, Momeny M, Bashash D, Zekri A, Alimoghaddam K, Ghavamzadeh A.

Asian Pac J Cancer Prev. 2016;17(3):1553-64.


Arsenic Trioxide Promotes Paclitaxel Cytotoxicity in Resistant Breast Cancer Cells.

Bakhshaiesh TO, Armat M, Shanehbandi D, Sharifi S, Baradaran B, Hejazi MS, Samadi N.

Asian Pac J Cancer Prev. 2015;16(13):5191-7.


Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-κB signaling in cervical cancer.

Chang YW, Chen MW, Chiu CF, Hong CC, Cheng CC, Hsiao M, Chen CA, Wei LH, Su JL.

Ann Surg Oncol. 2014 Dec;21 Suppl 4:S687-95. doi: 10.1245/s10434-014-3812-5. Epub 2014 Jul 22.


MicroRNA-dependent regulation of PTEN after arsenic trioxide treatment in bladder cancer cell line T24.

Cao Y, Yu SL, Wang Y, Guo GY, Ding Q, An RH.

Tumour Biol. 2011 Feb;32(1):179-88. doi: 10.1007/s13277-010-0111-z. Epub 2010 Sep 21.


Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways.

Liao S, Xia J, Chen Z, Zhang S, Ahmad A, Miele L, Sarkar FH, Wang Z.

J Cell Biochem. 2011 Apr;112(4):1055-65. doi: 10.1002/jcb.23019.


Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth.

Jutooru I, Chadalapaka G, Sreevalsan S, Lei P, Barhoumi R, Burghardt R, Safe S.

Exp Cell Res. 2010 Aug 1;316(13):2174-88. doi: 10.1016/j.yexcr.2010.04.027. Epub 2010 May 8.


The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells.

Zheng Y, Zhou M, Ye A, Li Q, Bai Y, Zhang Q.

World J Surg Oncol. 2010 Apr 20;8:31. doi: 10.1186/1477-7819-8-31.


microRNA expression alteration after arsenic trioxide treatment in HepG-2 cells.

Meng XZ, Zheng TS, Chen X, Wang JB, Zhang WH, Pan SH, Jiang HC, Liu LX.

J Gastroenterol Hepatol. 2011 Jan;26(1):186-93. doi: 10.1111/j.1440-1746.2010.06317.x.


Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres.

Ding D, Lim KS, Eberhart CG.

Acta Neuropathol Commun. 2014 Mar 31;2:31. doi: 10.1186/2051-5960-2-31.


Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide.

Wang X, Gao P, Long M, Lin F, Wei JX, Ren JH, Yan L, He T, Han Y, Zhang HZ.

Med Oncol. 2011 Dec;28(4):1225-54. doi: 10.1007/s12032-010-9552-x. Epub 2010 May 11.


Arsenic trioxide-induced growth arrest of breast cancer MCF-7 cells involving FOXO3a and IκB kinase β expression and localization.

Liu W, Gong Y, Li H, Jiang G, Zhan S, Liu H, Wu Y.

Cancer Biother Radiopharm. 2012 Oct;27(8):504-12. doi: 10.1089/cbr.2012.1162. Epub 2012 Sep 18.


Arsenic Trioxide Inhibits Cell Growth and Invasion via Down- Regulation of Skp2 in Pancreatic Cancer Cells.

Gao JK, Wang LX, Long B, Ye XT, Su JN, Yin XY, Zhou XX, Wang ZW.

Asian Pac J Cancer Prev. 2015;16(9):3805-10.


Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways.

Ahmad A, Wang Z, Kong D, Ali R, Ali S, Banerjee S, Sarkar FH.

Breast Cancer Res Treat. 2011 Feb;126(1):15-25. doi: 10.1007/s10549-010-0883-2. Epub 2010 Apr 9. Retraction in: Ahmad A, Wang Z, Kong D, Ali R, Ali S, Banerjee S, Sarkar FH. Breast Cancer Res Treat. 2016 Aug;158(3):605.


Arsenic trioxide suppresses cell growth and migration via inhibition of miR-27a in breast cancer cells.

Zhang S, Ma C, Pang H, Zeng F, Cheng L, Fang B, Ma J, Shi Y, Hong H, Chen J, Wang Z, Xia J.

Biochem Biophys Res Commun. 2016 Jan 1;469(1):55-61. doi: 10.1016/j.bbrc.2015.11.071. Epub 2015 Nov 22.


Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.

Momeny M, Zakidizaji M, Ghasemi R, Dehpour AR, Rahimi-Balaei M, Abdolazimi Y, Ghavamzadeh A, Alimoghaddam K, Ghaffari SH.

Med Oncol. 2010 Sep;27(3):833-42. doi: 10.1007/s12032-009-9294-9. Epub 2009 Sep 10.


Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways.

Wang Z, Li Y, Banerjee S, Kong D, Ahmad A, Nogueira V, Hay N, Sarkar FH.

J Cell Biochem. 2010 Mar 1;109(4):726-36. doi: 10.1002/jcb.22451. Erratum in: J Cell Biochem. 2016 Aug;117(8):1960.


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