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Items: 1 to 20 of 211

1.

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.

Wang C, Lee JE, Cho YW, Xiao Y, Jin Q, Liu C, Ge K.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15324-9. Epub 2012 Sep 4.

2.

KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.

Shpargel KB, Starmer J, Yee D, Pohlers M, Magnuson T.

PLoS Genet. 2014 Aug 7;10(8):e1004507. doi: 10.1371/journal.pgen.1004507. eCollection 2014 Aug.

3.

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development.

Shpargel KB, Sengoku T, Yokoyama S, Magnuson T.

PLoS Genet. 2012 Sep;8(9):e1002964. doi: 10.1371/journal.pgen.1002964. Epub 2012 Sep 27.

4.

Utx is required for proper induction of ectoderm and mesoderm during differentiation of embryonic stem cells.

Morales Torres C, Laugesen A, Helin K.

PLoS One. 2013;8(4):e60020. doi: 10.1371/journal.pone.0060020. Epub 2013 Apr 3.

5.

Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells.

Ohtani K, Zhao C, Dobreva G, Manavski Y, Kluge B, Braun T, Rieger MA, Zeiher AM, Dimmeler S.

Circ Res. 2013 Sep 13;113(7):856-62. doi: 10.1161/CIRCRESAHA.113.302035. Epub 2013 Jul 15.

6.

UTX demethylase activity is required for satellite cell-mediated muscle regeneration.

Faralli H, Wang C, Nakka K, Benyoucef A, Sebastian S, Zhuang L, Chu A, Palii CG, Liu C, Camellato B, Brand M, Ge K, Dilworth FJ.

J Clin Invest. 2016 Apr 1;126(4):1555-65. doi: 10.1172/JCI83239. Epub 2016 Mar 21.

7.

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner.

Welstead GG, Creyghton MP, Bilodeau S, Cheng AW, Markoulaki S, Young RA, Jaenisch R.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13004-9. doi: 10.1073/pnas.1210787109. Epub 2012 Jul 23.

8.

The histone demethylase UTX regulates stem cell migration and hematopoiesis.

Thieme S, Gyárfás T, Richter C, Özhan G, Fu J, Alexopoulou D, Muders MH, Michalk I, Jakob C, Dahl A, Klink B, Bandola J, Bachmann M, Schröck E, Buchholz F, Stewart AF, Weidinger G, Anastassiadis K, Brenner S.

Blood. 2013 Mar 28;121(13):2462-73. doi: 10.1182/blood-2012-08-452003. Epub 2013 Jan 30.

9.

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.

Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW, Barlev N, Bradley A, Cowley SM.

Mol Cell Biol. 2010 Oct;30(20):4851-63. doi: 10.1128/MCB.00521-10. Epub 2010 Aug 16.

10.

Retinoic acid dependent histone 3 demethylation of the clustered HOX genes during neural differentiation of human embryonic stem cells.

Shahhoseini M, Taghizadeh Z, Hatami M, Baharvand H.

Biochem Cell Biol. 2013 Apr;91(2):116-22. doi: 10.1139/bcb-2012-0049. Epub 2012 Nov 14.

PMID:
23527641
11.

The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity.

Vandamme J, Lettier G, Sidoli S, Di Schiavi E, Nørregaard Jensen O, Salcini AE.

PLoS Genet. 2012;8(5):e1002647. doi: 10.1371/journal.pgen.1002647. Epub 2012 May 3.

12.

Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells.

Evans AL, Faial T, Gilchrist MJ, Down T, Vallier L, Pedersen RA, Wardle FC, Smith JC.

PLoS One. 2012;7(3):e33346. doi: 10.1371/journal.pone.0033346. Epub 2012 Mar 30.

13.

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.

Mansour AA, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, Krupalnik V, Zerbib M, Amann-Zalcenstein D, Maza I, Geula S, Viukov S, Holtzman L, Pribluda A, Canaani E, Horn-Saban S, Amit I, Novershtern N, Hanna JH.

Nature. 2012 Aug 16;488(7411):409-13. doi: 10.1038/nature11272.

PMID:
22801502
14.

Id1 maintains embryonic stem cell self-renewal by up-regulation of Nanog and repression of Brachyury expression.

Romero-Lanman EE, Pavlovic S, Amlani B, Chin Y, Benezra R.

Stem Cells Dev. 2012 Feb 10;21(3):384-93. doi: 10.1089/scd.2011.0428. Epub 2011 Dec 1.

PMID:
22013995
15.

Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation.

Manna S, Kim JK, Baugé C, Cam M, Zhao Y, Shetty J, Vacchio MS, Castro E, Tran B, Tessarollo L, Bosselut R.

Nat Commun. 2015 Sep 2;6:8152. doi: 10.1038/ncomms9152.

16.

Expression profiles of histone lysine demethylases during cardiomyocyte differentiation of mouse embryonic stem cells.

Tang Y, Chen ZY, Hong YZ, Wu Q, Lin HQ, Chen CD, Yang HT.

Acta Pharmacol Sin. 2014 Jul;35(7):899-906. doi: 10.1038/aps.2014.40.

17.

The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells.

Kriz V, Agren N, Lindholm CK, Lenell S, Saldeen J, Mares J, Welsh M.

J Biol Chem. 2006 Nov 10;281(45):34484-91. Epub 2006 Sep 12.

18.

The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation.

Zha L, Li F, Wu R, Artinian L, Rehder V, Yu L, Liang H, Xue B, Shi H.

J Biol Chem. 2015 Oct 9;290(41):25151-63. doi: 10.1074/jbc.M115.662650. Epub 2015 Aug 25.

19.

Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.

Miller SA, Mohn SE, Weinmann AS.

Mol Cell. 2010 Nov 24;40(4):594-605. doi: 10.1016/j.molcel.2010.10.028.

20.

A histone H3 lysine 27 demethylase regulates animal posterior development.

Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y.

Nature. 2007 Oct 11;449(7163):689-94. Epub 2007 Sep 12.

PMID:
17851529

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