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Myofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells.

Kim TI, Poulin EJ, Blask E, Bukhalid R, Whitehead RH, Franklin JL, Coffey RJ.

Growth Factors. 2012 Oct;30(5):320-32. Epub 2012 Sep 5.


Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.

Damstrup L, Kuwada SK, Dempsey PJ, Brown CL, Hawkey CJ, Poulsen HS, Wiley HS, Coffey RJ Jr.

Br J Cancer. 1999 Jun;80(7):1012-9.


Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance.

Singh AB, Sugimoto K, Dhawan P, Harris RC.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1660-8. Epub 2007 Sep 13.


Aldosterone induces myofibroblast EGF secretion to regulate epithelial colonic permeability.

Miró L, Pérez-Bosque A, Maijó M, Amat C, Naftalin RJ, Moretó M.

Am J Physiol Cell Physiol. 2013 May 1;304(9):C918-26. doi: 10.1152/ajpcell.00292.2012. Epub 2013 Mar 6.


Human colon fibroblasts induce differentiation and proliferation of intestinal epithelial cells through the direct paracrine action of keratinocyte growth factor.

Visco V, Bava FA, d'Alessandro F, Cavallini M, Ziparo V, Torrisi MR.

J Cell Physiol. 2009 Jul;220(1):204-13. doi: 10.1002/jcp.21752.


Autophagy enhances intestinal epithelial tight junction barrier function by targeting claudin-2 protein degradation.

Nighot PK, Hu CA, Ma TY.

J Biol Chem. 2015 Mar 13;290(11):7234-46. doi: 10.1074/jbc.M114.597492. Epub 2015 Jan 23.


KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin.

Richardson GD, Bazzi H, Fantauzzo KA, Waters JM, Crawford H, Hynd P, Christiano AM, Jahoda CA.

Development. 2009 Jul;136(13):2153-64. doi: 10.1242/dev.031427. Epub 2009 May 27.


Conditioned medium from LS 174T goblet cells treated with oxyresveratrol strengthens tight junctions in Caco-2 cells.

Hwang D, Jo H, Hwang S, Kim JK, Kim IH, Lim YH.

Biomed Pharmacother. 2017 Jan;85:280-286. doi: 10.1016/j.biopha.2016.11.022. Epub 2016 Nov 18.


Fucoidan enhances intestinal barrier function by upregulating the expression of claudin-1.

Iraha A, Chinen H, Hokama A, Yonashiro T, Kinjo T, Kishimoto K, Nakamoto M, Hirata T, Kinjo N, Higa F, Tateyama M, Kinjo F, Fujita J.

World J Gastroenterol. 2013 Sep 7;19(33):5500-7. doi: 10.3748/wjg.v19.i33.5500.


Glucagon like peptide-2 induces intestinal restitution through VEGF release from subepithelial myofibroblasts.

Bulut K, Pennartz C, Felderbauer P, Meier JJ, Banasch M, Bulut D, Schmitz F, Schmidt WE, Hoffmann P.

Eur J Pharmacol. 2008 Jan 14;578(2-3):279-85. Epub 2007 Sep 15.


GLP-2 enhances barrier formation and attenuates TNFα-induced changes in a Caco-2 cell model of the intestinal barrier.

Moran GW, O'Neill C, McLaughlin JT.

Regul Pept. 2012 Oct 10;178(1-3):95-101. doi: 10.1016/j.regpep.2012.07.002. Epub 2012 Jul 15.


Keratinocyte growth factor enhances barrier function without altering claudin expression in primary alveolar epithelial cells.

LaFemina MJ, Rokkam D, Chandrasena A, Pan J, Bajaj A, Johnson M, Frank JA.

Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L724-34. doi: 10.1152/ajplung.00233.2010. Epub 2010 Sep 10.


Control of tight junctional sealing: role of epidermal growth factor.

Flores-Benítez D, Ruiz-Cabrera A, Flores-Maldonado C, Shoshani L, Cereijido M, Contreras RG.

Am J Physiol Renal Physiol. 2007 Feb;292(2):F828-36. Epub 2006 Oct 31.


Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers.

Morita H, Katsuno T, Hoshimoto A, Hirano N, Saito Y, Suzuki Y.

Exp Cell Res. 2004 Aug 1;298(1):1-8.


Amphiregulin promotes intestinal epithelial regeneration: roles of intestinal subepithelial myofibroblasts.

Shao J, Sheng H.

Endocrinology. 2010 Aug;151(8):3728-37. doi: 10.1210/en.2010-0319. Epub 2010 Jun 9.


Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells.

Amasheh S, Schmidt T, Mahn M, Florian P, Mankertz J, Tavalali S, Gitter AH, Schulzke JD, Fromm M.

Cell Tissue Res. 2005 Jul;321(1):89-96.


Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers.

Zhang C, Yan J, Xiao Y, Shen Y, Wang J, Ge W, Chen Y.

Int J Mol Sci. 2017 Jan 17;18(1). pii: E157. doi: 10.3390/ijms18010157.

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