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Items: 1 to 20 of 102


Adeno-associated virus-coated allografts: a novel approach for cranioplasty.

Ben Arav A, Pelled G, Zilberman Y, Kimelman-Bleich N, Gazit Z, Schwarz EM, Gazit D.

J Tissue Eng Regen Med. 2012 Nov;6(10):e43-50. doi: 10.1002/term.1594. Epub 2012 Sep 3.


Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur.

Yazici C, Takahata M, Reynolds DG, Xie C, Samulski RJ, Samulski J, Beecham EJ, Gertzman AA, Spilker M, Zhang X, O'Keefe RJ, Awad HA, Schwarz EM.

Mol Ther. 2011 Aug;19(8):1416-25. doi: 10.1038/mt.2010.294. Epub 2011 Jan 4.


Biological effects of rAAV-caAlk2 coating on structural allograft healing.

Koefoed M, Ito H, Gromov K, Reynolds DG, Awad HA, Rubery PT, Ulrich-Vinther M, Soballe K, Guldberg RE, Lin AS, O'Keefe RJ, Zhang X, Schwarz EM.

Mol Ther. 2005 Aug;12(2):212-8.


The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings.

Yazici C, Yanoso L, Xie C, Reynolds DG, Samulski RJ, Samulski J, Yannariello-Brown J, Gertzman AA, Zhang X, Awad HA, Schwarz EM.

Biomaterials. 2008 Oct;29(28):3882-7. doi: 10.1016/j.biomaterials.2008.06.007. Epub 2008 Jun 30.


Synthetic scaffold coating with adeno-associated virus encoding BMP2 to promote endogenous bone repair.

Dupont KM, Boerckel JD, Stevens HY, Diab T, Kolambkar YM, Takahata M, Schwarz EM, Guldberg RE.

Cell Tissue Res. 2012 Mar;347(3):575-88. doi: 10.1007/s00441-011-1197-3. Epub 2011 Jun 22.


Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system.

Gafni Y, Pelled G, Zilberman Y, Turgeman G, Apparailly F, Yotvat H, Galun E, Gazit Z, Jorgensen C, Gazit D.

Mol Ther. 2004 Apr;9(4):587-95.


PTH promotes allograft integration in a calvarial bone defect.

Sheyn D, Cohn Yakubovich D, Kallai I, Su S, Da X, Pelled G, Tawackoli W, Cook-Weins G, Schwarz EM, Gazit D, Gazit Z.

Mol Pharm. 2013 Dec 2;10(12):4462-71. doi: 10.1021/mp400292p. Epub 2013 Nov 8.


Combination of adeno-associated virus and adenovirus vectors expressing bone morphogenetic protein-2 produces enhanced osteogenic activity in immunocompetent rats.

Chen Y, Luk KD, Cheung KM, Lu WW, An XM, Ng SS, Lin MC, Kung HF.

Biochem Biophys Res Commun. 2004 May 7;317(3):675-81.


Recent advances in gene delivery for structural bone allografts.

Awad HA, Zhang X, Reynolds DG, Guldberg RE, O'Keefe RJ, Schwarz EM.

Tissue Eng. 2007 Aug;13(8):1973-85. Review.


Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts.

Cohn Yakubovich D, Tawackoli W, Sheyn D, Kallai I, Da X, Pelled G, Gazit D, Gazit Z.

J Vis Exp. 2015 Dec 22;(106):e53459. doi: 10.3791/53459.


The Angiopoietin-1 Variant COMP-Ang1 Enhances BMP2-Induced Bone Regeneration with Recruiting Pericytes in Critical Sized Calvarial Defects.

Choi H, Jeong BC, Hur SW, Kim JW, Lee KB, Koh JT.

PLoS One. 2015 Oct 14;10(10):e0140502. doi: 10.1371/journal.pone.0140502. eCollection 2015.


Bone morphogenetic protein 2 gene transduction enhances the osteogenic potential of human urine-derived stem cells.

Guan J, Zhang J, Zhu Z, Niu X, Guo S, Wang Y, Zhang C.

Stem Cell Res Ther. 2015 Jan 7;6:5. doi: 10.1186/scrt539.


Augmented healing of critical-size calvarial defects by baculovirus-engineered MSCs that persistently express growth factors.

Lin CY, Chang YH, Kao CY, Lu CH, Sung LY, Yen TC, Lin KJ, Hu YC.

Biomaterials. 2012 May;33(14):3682-92. doi: 10.1016/j.biomaterials.2012.02.007. Epub 2012 Feb 22.


Gene therapy for new bone formation using adeno-associated viral bone morphogenetic protein-2 vectors.

Chen Y, Luk KD, Cheung KM, Xu R, Lin MC, Lu WW, Leong JC, Kung HF.

Gene Ther. 2003 Aug;10(16):1345-53.


Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model.

Zhu W, Rawlins BA, Boachie-Adjei O, Myers ER, Arimizu J, Choi E, Lieberman JR, Crystal RG, Hidaka C.

J Bone Miner Res. 2004 Dec;19(12):2021-32. Epub 2004 Aug 30.


Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells.

Lee SJ, Kang SW, Do HJ, Han I, Shin DA, Kim JH, Lee SH.

Biomaterials. 2010 Jul;31(21):5652-9. doi: 10.1016/j.biomaterials.2010.03.019. Epub 2010 Apr 21.


Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery.

Basile P, Dadali T, Jacobson J, Hasslund S, Ulrich-Vinther M, Søballe K, Nishio Y, Drissi MH, Langstein HN, Mitten DJ, O'Keefe RJ, Schwarz EM, Awad HA.

Mol Ther. 2008 Mar;16(3):466-73. doi: 10.1038/ Epub 2008 Jan 8.


Fibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice.

Xiao L, Ueno D, Catros S, Homer-Bouthiette C, Charles L, Kuhn L, Hurley MM.

Endocrinology. 2014 Mar;155(3):965-74. doi: 10.1210/en.2013-1919. Epub 2014 Jan 9.


Comparative efficacy of dermal fibroblast-mediated and direct adenoviral bone morphogenetic protein-2 gene therapy for bone regeneration in an equine rib model.

Ishihara A, Zekas LJ, Weisbrode SE, Bertone AL.

Gene Ther. 2010 Jun;17(6):733-44. doi: 10.1038/gt.2010.13. Epub 2010 Mar 11.


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