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Items: 1 to 20 of 141


Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A.

Kelly RD, Mahmud A, McKenzie M, Trounce IA, St John JC.

Nucleic Acids Res. 2012 Nov 1;40(20):10124-38. doi: 10.1093/nar/gks770. Epub 2012 Aug 31.


Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny.

Lee W, Johnson J, Gough DJ, Donoghue J, Cagnone GL, Vaghjiani V, Brown KA, Johns TG, St John JC.

Cell Death Dis. 2015 Feb 26;6:e1664. doi: 10.1038/cddis.2015.34.


The effects of nuclear reprogramming on mitochondrial DNA replication.

Kelly RD, Sumer H, McKenzie M, Facucho-Oliveira J, Trounce IA, Verma PJ, St John JC.

Stem Cell Rev. 2013 Feb;9(1):1-15. doi: 10.1007/s12015-011-9318-7.


The control of mitochondrial DNA replication during development and tumorigenesis.

Lee WT, St John J.

Ann N Y Acad Sci. 2015 Sep;1350:95-106. doi: 10.1111/nyas.12873. Epub 2015 Sep 3. Review.


Mitochondrial DNA replication during differentiation of murine embryonic stem cells.

Facucho-Oliveira JM, Alderson J, Spikings EC, Egginton S, St John JC.

J Cell Sci. 2007 Nov 15;120(Pt 22):4025-34. Epub 2007 Oct 30.


Analysis of Mitochondrial DNA Copy Number and Its Regulation Through DNA Methylation of POLGA.

Sun X, Lee W, Vaghjiani V, St John JC.

Methods Mol Biol. 2016;1351:131-41. doi: 10.1007/978-1-4939-3040-1_10.


Analysis of Mitochondrial DNA in Induced Pluripotent and Embryonic Stem Cells.

Lee W, Kelly RD, Yeung KY, Cagnone G, McKenzie M, St John JC.

Methods Mol Biol. 2015;1330:219-52. doi: 10.1007/978-1-4939-2848-4_18.


Genome-wide DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) residing in mouse pluripotent stem cells.

Sato S, Yagi S, Arai Y, Hirabayashi K, Hattori N, Iwatani M, Okita K, Ohgane J, Tanaka S, Wakayama T, Yamanaka S, Shiota K.

Genes Cells. 2010 Jun;15(6):607-18. doi: 10.1111/j.1365-2443.2010.01404.x. Epub 2010 May 13.


Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells.

Sommer CA, Christodoulou C, Gianotti-Sommer A, Shen SS, Sailaja BS, Hezroni H, Spira A, Meshorer E, Kotton DN, Mostoslavsky G.

PLoS One. 2012;7(12):e51711. doi: 10.1371/journal.pone.0051711. Epub 2012 Dec 14.


No correlation between mtDNA amount and methylation levels at the CpG island of POLG exon 2 in wild-type and mutant human differentiated cells.

Steffann J, Pouliet A, Adjal H, Bole C, Fourrage C, Martinovic J, Rolland-Galmiche L, Rotig A, Tores F, Munnich A, Bonnefont JP.

J Med Genet. 2017 May;54(5):324-329. doi: 10.1136/jmedgenet-2016-104335. Epub 2017 Jan 9.


Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development.

Spikings EC, Alderson J, St John JC.

Biol Reprod. 2007 Feb;76(2):327-35. Epub 2006 Oct 11.


Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis.

Hance N, Ekstrand MI, Trifunovic A.

Hum Mol Genet. 2005 Jul 1;14(13):1775-83. Epub 2005 May 11.


Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis.

Tajbakhsh J, Stefanovski D, Tang G, Wawrowsky K, Liu N, Fair JH.

Exp Cell Res. 2015 Mar 15;332(2):190-201. doi: 10.1016/j.yexcr.2015.02.004. Epub 2015 Feb 17.


Targeting cellular memory to reprogram the epigenome, restore potential, and improve somatic cell nuclear transfer.

Eilertsen KJ, Power RA, Harkins LL, Misica P.

Anim Reprod Sci. 2007 Mar;98(1-2):129-46. Epub 2006 Oct 21. Review.


Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool.

Iacobazzi V, Castegna A, Infantino V, Andria G.

Mol Genet Metab. 2013 Sep-Oct;110(1-2):25-34. doi: 10.1016/j.ymgme.2013.07.012. Epub 2013 Jul 19. Review.


Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells.

Kubiura M, Okano M, Kimura H, Kawamura F, Tada M.

Chromosome Res. 2012 Oct;20(7):837-48. doi: 10.1007/s10577-012-9317-9. Epub 2012 Oct 31.


DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei.

Simonsson S, Gurdon J.

Nat Cell Biol. 2004 Oct;6(10):984-90. Epub 2004 Sep 26.


DNA methylation is required for silencing of ant4, an adenine nucleotide translocase selectively expressed in mouse embryonic stem cells and germ cells.

Rodić N, Oka M, Hamazaki T, Murawski MR, Jorgensen M, Maatouk DM, Resnick JL, Li E, Terada N.

Stem Cells. 2005 Oct;23(9):1314-23. Epub 2005 Jul 28.


Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells.

Kelly RD, Rodda AE, Dickinson A, Mahmud A, Nefzger CM, Lee W, Forsythe JS, Polo JM, Trounce IA, McKenzie M, Nisbet DR, St John JC.

Stem Cells. 2013 Apr;31(4):703-16. doi: 10.1002/stem.1313.


Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation.

Cho HJ, Lee CS, Kwon YW, Paek JS, Lee SH, Hur J, Lee EJ, Roh TY, Chu IS, Leem SH, Kim Y, Kang HJ, Park YB, Kim HS.

Blood. 2010 Jul 22;116(3):386-95. doi: 10.1182/blood-2010-02-269589. Epub 2010 May 3.

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