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Items: 1 to 20 of 141

1.

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

Andersson SA, Olsson AH, Esguerra JL, Heimann E, Ladenvall C, Edlund A, Salehi A, Taneera J, Degerman E, Groop L, Ling C, Eliasson L.

Mol Cell Endocrinol. 2012 Nov 25;364(1-2):36-45. doi: 10.1016/j.mce.2012.08.009. Epub 2012 Aug 23.

2.

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.

Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH.

Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009.

3.

Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes.

Olsson AH, Yang BT, Hall E, Taneera J, Salehi A, Nitert MD, Ling C.

Eur J Endocrinol. 2011 Oct;165(4):589-95. doi: 10.1530/EJE-11-0282. Epub 2011 Jul 20.

4.

Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat.

Esguerra JL, Bolmeson C, Cilio CM, Eliasson L.

PLoS One. 2011 Apr 7;6(4):e18613. doi: 10.1371/journal.pone.0018613.

5.

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

Dayeh T, Volkov P, Salö S, Hall E, Nilsson E, Olsson AH, Kirkpatrick CL, Wollheim CB, Eliasson L, Rönn T, Bacos K, Ling C.

PLoS Genet. 2014 Mar 6;10(3):e1004160. doi: 10.1371/journal.pgen.1004160. eCollection 2014 Mar.

6.

Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia.

Taneera J, Fadista J, Ahlqvist E, Atac D, Ottosson-Laakso E, Wollheim CB, Groop L.

Hum Mol Genet. 2015 Apr 1;24(7):1945-55. doi: 10.1093/hmg/ddu610. Epub 2014 Dec 8.

7.

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.

Ling C, Del Guerra S, Lupi R, Rönn T, Granhall C, Luthman H, Masiello P, Marchetti P, Groop L, Del Prato S.

Diabetologia. 2008 Apr;51(4):615-22. doi: 10.1007/s00125-007-0916-5. Epub 2008 Feb 13.

8.
10.

Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.

Hall E, Volkov P, Dayeh T, Bacos K, Rönn T, Nitert MD, Ling C.

BMC Med. 2014 Jun 23;12:103. doi: 10.1186/1741-7015-12-103.

11.

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.

Koeck T, Olsson AH, Nitert MD, Sharoyko VV, Ladenvall C, Kotova O, Reiling E, Rönn T, Parikh H, Taneera J, Eriksson JG, Metodiev MD, Larsson NG, Balhuizen A, Luthman H, Stančáková A, Kuusisto J, Laakso M, Poulsen P, Vaag A, Groop L, Lyssenko V, Mulder H, Ling C.

Cell Metab. 2011 Jan 5;13(1):80-91. doi: 10.1016/j.cmet.2010.12.007.

12.

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.

Taneera J, Lang S, Sharma A, Fadista J, Zhou Y, Ahlqvist E, Jonsson A, Lyssenko V, Vikman P, Hansson O, Parikh H, Korsgren O, Soni A, Krus U, Zhang E, Jing XJ, Esguerra JL, Wollheim CB, Salehi A, Rosengren A, Renström E, Groop L.

Cell Metab. 2012 Jul 3;16(1):122-34. doi: 10.1016/j.cmet.2012.06.006.

13.

Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.

Ling C, Groop L, Guerra SD, Lupi R.

PLoS One. 2009 Aug 18;4(8):e6558. doi: 10.1371/journal.pone.0006558.

14.

Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects.

Riva M, Nitert MD, Voss U, Sathanoori R, Lindqvist A, Ling C, Wierup N.

Cell Tissue Res. 2011 Dec;346(3):393-405. doi: 10.1007/s00441-011-1268-5. Epub 2011 Nov 23.

PMID:
22108805
15.

Regulation of core clock genes in human islets.

Stamenkovic JA, Olsson AH, Nagorny CL, Malmgren S, Dekker-Nitert M, Ling C, Mulder H.

Metabolism. 2012 Jul;61(7):978-85. doi: 10.1016/j.metabol.2011.11.013. Epub 2012 Feb 2.

PMID:
22304835
18.

A common variant upstream of the PAX6 gene influences islet function in man.

Ahlqvist E, Turrini F, Lang ST, Taneera J, Zhou Y, Almgren P, Hansson O, Isomaa B, Tuomi T, Eriksson K, Eriksson JG, Lyssenko V, Groop L.

Diabetologia. 2012 Jan;55(1):94-104. doi: 10.1007/s00125-011-2300-8. Epub 2011 Sep 16.

PMID:
21922321
19.

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.

PMID:
17906960
20.

Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats.

Rose T, Efendic S, Rupnik M.

J Gen Physiol. 2007 Jun;129(6):493-508.

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