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Items: 1 to 20 of 65

1.

HS-173, a novel phosphatidylinositol 3-kinase (PI3K) inhibitor, has anti-tumor activity through promoting apoptosis and inhibiting angiogenesis.

Lee H, Jung KH, Jeong Y, Hong S, Hong SS.

Cancer Lett. 2013 Jan 1;328(1):152-9. doi: 10.1016/j.canlet.2012.08.020. Epub 2012 Aug 26.

PMID:
22929971
2.

HS-116, a novel phosphatidylinositol 3-kinase inhibitor induces apoptosis and suppresses angiogenesis of hepatocellular carcinoma through inhibition of the PI3K/AKT/mTOR pathway.

Jung KH, Choi MJ, Hong S, Lee H, Hong SW, Zheng HM, Lee HS, Hong S, Hong SS.

Cancer Lett. 2012 Mar 28;316(2):187-95. doi: 10.1016/j.canlet.2011.10.037. Epub 2011 Nov 4.

PMID:
22182943
3.

A novel imidazopyridine derivative, HS-106, induces apoptosis of breast cancer cells and represses angiogenesis by targeting the PI3K/mTOR pathway.

Li GY, Jung KH, Lee H, Son MK, Seo J, Hong SW, Jeong Y, Hong S, Hong SS.

Cancer Lett. 2013 Feb 1;329(1):59-67. doi: 10.1016/j.canlet.2012.10.013. Epub 2012 Oct 17.

PMID:
23085493
4.

Suppression of tumor proliferation and angiogenesis of hepatocellular carcinoma by HS-104, a novel phosphoinositide 3-kinase inhibitor.

Jung KH, Zheng HM, Jeong Y, Choi MJ, Lee H, Hong SW, Lee HS, Son MK, Lee S, Hong S, Hong SS.

Cancer Lett. 2013 Jan 1;328(1):176-87. doi: 10.1016/j.canlet.2012.08.005. Epub 2012 Aug 15.

PMID:
22902995
5.

Synergistic anticancer activity of HS-173, a novel PI3K inhibitor in combination with Sorafenib against pancreatic cancer cells.

Yun SM, Jung KH, Lee H, Son MK, Seo JH, Yan HH, Park BH, Hong S, Hong SS.

Cancer Lett. 2013 May 1;331(2):250-61. doi: 10.1016/j.canlet.2013.01.007. Epub 2013 Jan 20.

PMID:
23340175
6.

A novel imidazopyridine analogue as a phosphatidylinositol 3-kinase inhibitor against human breast cancer.

Lee H, Li GY, Jeong Y, Jung KH, Lee JH, Ham K, Hong S, Hong SS.

Cancer Lett. 2012 May 1;318(1):68-75. doi: 10.1016/j.canlet.2011.12.001. Epub 2011 Dec 8.

PMID:
22155744
7.

Anti-cancer effect of HS-345, a new tropomyosin-related kinase A inhibitor, on human pancreatic cancer.

Seo JH, Jung KH, Son MK, Yan HH, Ryu YL, Kim J, Lee JK, Hong S, Hong SS.

Cancer Lett. 2013 Sep 28;338(2):271-81. doi: 10.1016/j.canlet.2013.04.002. Epub 2013 Apr 13.

PMID:
23587795
8.

Induction of apoptosis and suppression of angiogenesis of hepatocellular carcinoma by HS-159, a novel phosphatidylinositol 3-kinase inhibitor.

Yun SM, Lee JH, Jung KH, Lee H, Lee S, Hong S, Hong SS.

Int J Oncol. 2013 Jul;43(1):201-9. doi: 10.3892/ijo.2013.1912. Epub 2013 Apr 22.

PMID:
23604199
9.

Anticancer activity of HS-527, a novel inhibitor targeting PI3-kinase in human pancreatic cancer cells.

Ryu YL, Jung KH, Son MK, Yan HH, Kim SJ, Shin S, Hong S, Hong SS.

Cancer Lett. 2014 Oct 10;353(1):68-77. doi: 10.1016/j.canlet.2014.07.001. Epub 2014 Jul 10.

PMID:
25016056
10.

Anti-cancer effects of a novel compound HS-113 on cell growth, apoptosis, and angiogenesis in human hepatocellular carcinoma cells.

Choi MJ, Jung KH, Kim D, Lee H, Zheng HM, Park BH, Hong SW, Kim MH, Hong S, Hong SS.

Cancer Lett. 2011 Jul 28;306(2):190-6. doi: 10.1016/j.canlet.2011.03.005. Epub 2011 Apr 3.

PMID:
21463918
12.

Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.

Chia JS, Du JL, Hsu WB, Sun A, Chiang CP, Wang WB.

BMC Cancer. 2010 Apr 30;10:175. doi: 10.1186/1471-2407-10-175.

13.

Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization.

Meier T, Uhlik M, Chintharlapalli S, Dowless M, Van Horn R, Stewart J, Blosser W, Cook J, Young D, Ye X, Evans G, Credille K, Ballard D, Huber L, Capen A, Chedid M, Ilaria R Jr, Smith MC, Stancato L.

Mol Cancer Ther. 2011 Nov;10(11):2168-78. doi: 10.1158/1535-7163.MCT-11-0323. Epub 2011 Sep 8.

14.

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy.

Lee JH, Jung KH, Lee H, Son MK, Yun SM, Ahn SH, Lee KR, Lee S, Kim D, Hong S, Hong SS.

Oncotarget. 2014 Oct 30;5(20):10180-97.

15.

Antiangiogenic effect of ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor.

Kong D, Okamura M, Yoshimi H, Yamori T.

Eur J Cancer. 2009 Mar;45(5):857-65. doi: 10.1016/j.ejca.2008.12.007. Epub 2009 Jan 12.

PMID:
19144509
16.

Acidic mucopolysaccharide from Holothuria leucospilota has antitumor effect by inhibiting angiogenesis and tumor cell invasion in vivo and in vitro.

Zhang W, Lu Y, Xu B, Wu J, Zhang L, Gao M, Zheng S, Wang A, Zhang C, Chen L, Lei N.

Cancer Biol Ther. 2009 Aug;8(15):1489-99. Epub 2009 Aug 8.

PMID:
19483477
17.

Antitumor and antiangiogenic activities of BMS-690514, an inhibitor of human EGF and VEGF receptor kinase families.

Wong TW, Lee FY, Emanuel S, Fairchild C, Fargnoli J, Fink B, Gavai A, Hammell A, Henley B, Hilt C, Hunt JT, Krishnan B, Kukral D, Lewin A, Malone H, Norris D, Oppenheimer S, Vite G, Yu C.

Clin Cancer Res. 2011 Jun 15;17(12):4031-41. doi: 10.1158/1078-0432.CCR-10-3417. Epub 2011 Apr 29.

18.

Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenesis.

Paradziej-Łukowicz J, Skwarska A, Peszyńska-Sularz G, Brillowska-Dąbrowska A, Konopa J.

Cancer Biol Ther. 2011 Oct 1;12(7):586-97. Epub 2011 Oct 1.

PMID:
21775820
19.

Penta-O-galloyl-beta-D-glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of cyclooxygenase-2 and mitogen-activated protein kinase pathways.

Huh JE, Lee EO, Kim MS, Kang KS, Kim CH, Cha BC, Surh YJ, Kim SH.

Carcinogenesis. 2005 Aug;26(8):1436-45. Epub 2005 Apr 21.

PMID:
15845650
20.

The effect of HS-111, a novel thiazolamine derivative, on apoptosis and angiogenesis of hepatocellular carcinoma cells.

Choi MJ, Lee H, Lee JH, Jung KH, Kim D, Hong S, Hong SS.

Arch Pharm Res. 2012 Mar;35(4):747-54. doi: 10.1007/s12272-012-0420-4. Epub 2012 May 3.

PMID:
22553069

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