Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 104

1.

Molecular determinants of A2AR-D2R allosterism: role of the intracellular loop 3 of the D2R.

Fernández-Dueñas V, Gómez-Soler M, Jacobson KA, Kumar ST, Fuxe K, Borroto-Escuela DO, Ciruela F.

J Neurochem. 2012 Nov;123(3):373-84. doi: 10.1111/j.1471-4159.2012.07956.x.

2.

Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer.

Bonaventura J, Navarro G, Casadó-Anguera V, Azdad K, Rea W, Moreno E, Brugarolas M, Mallol J, Canela EI, Lluís C, Cortés A, Volkow ND, Schiffmann SN, Ferré S, Casadó V.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3609-18. doi: 10.1073/pnas.1507704112.

3.

Dopamine D(2) receptor-mediated modulation of adenosine A(2A) receptor agonist binding within the A(2A)R/D(2)R oligomer framework.

Fernández-Dueñas V, Gómez-Soler M, Morató X, Núñez F, Das A, Kumar TS, Jaumà S, Jacobson KA, Ciruela F.

Neurochem Int. 2013 Jul;63(1):42-6. doi: 10.1016/j.neuint.2013.04.006.

4.

Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices.

Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K.

Biochem Biophys Res Commun. 2010 Nov 26;402(4):801-7. doi: 10.1016/j.bbrc.2010.10.122.

PMID:
21040702
5.

A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R.

Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K.

Biochem Biophys Res Commun. 2010 Mar 26;394(1):222-7. doi: 10.1016/j.bbrc.2010.02.168.

PMID:
20197060
6.

Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer.

Marcellino D, Navarro G, Sahlholm K, Nilsson J, Agnati LF, Canela EI, Lluís C, Århem P, Franco R, Fuxe K.

Biochem Biophys Res Commun. 2010 Apr 16;394(4):988-92. doi: 10.1016/j.bbrc.2010.03.104.

PMID:
20307491
7.

Modulation of A₂a receptor antagonist on D₂ receptor internalization and ERK phosphorylation.

Huang L, Wu DD, Zhang L, Feng LY.

Acta Pharmacol Sin. 2013 Oct;34(10):1292-300. doi: 10.1038/aps.2013.87.

8.
9.

Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers.

Navarro G, Aguinaga D, Moreno E, Hradsky J, Reddy PP, Cortés A, Mallol J, Casadó V, Mikhaylova M, Kreutz MR, Lluís C, Canela EI, McCormick PJ, Ferré S.

Chem Biol. 2014 Nov 20;21(11):1546-56. doi: 10.1016/j.chembiol.2014.10.004.

10.

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors.

Navarro G, Aymerich MS, Marcellino D, Cortés A, Casadó V, Mallol J, Canela EI, Agnati L, Woods AS, Fuxe K, Lluís C, Lanciego JL, Ferré S, Franco R.

J Biol Chem. 2009 Oct 9;284(41):28058-68. doi: 10.1074/jbc.M109.034231.

11.

Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers.

Soriano A, Ventura R, Molero A, Hoen R, Casadó V, Cortés A, Fanelli F, Albericio F, Lluís C, Franco R, Royo M.

J Med Chem. 2009 Sep 24;52(18):5590-602. doi: 10.1021/jm900298c.

PMID:
19711895
12.

On the existence of a possible A2A-D2-β-Arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment.

Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Ciruela F, Agnati LF, Fuxe K.

J Mol Biol. 2011 Mar 11;406(5):687-99. doi: 10.1016/j.jmb.2011.01.022.

PMID:
21256133
13.

Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.

Borroto-Escuela DO, Ravani A, Tarakanov AO, Brito I, Narvaez M, Romero-Fernandez W, Corrales F, Agnati LF, Tanganelli S, Ferraro L, Fuxe K.

Biochem Biophys Res Commun. 2013 May 24;435(1):140-6. doi: 10.1016/j.bbrc.2013.04.058.

PMID:
23624386
14.

Ligand-dependent oligomerization of dopamine D(2) and adenosine A(2A) receptors in living neuronal cells.

Vidi PA, Chemel BR, Hu CD, Watts VJ.

Mol Pharmacol. 2008 Sep;74(3):544-51. doi: 10.1124/mol.108.047472.

15.

Evidence for the heterotetrameric structure of the adenosine A2A-dopamine D2 receptor complex.

Casadó-Anguera V, Bonaventura J, Moreno E, Navarro G, Cortés A, Ferré S, Casadó V.

Biochem Soc Trans. 2016 Apr 15;44(2):595-600. doi: 10.1042/BST20150276. Review.

PMID:
27068975
16.

Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cells.

Cabello N, Gandía J, Bertarelli DC, Watanabe M, Lluís C, Franco R, Ferré S, Luján R, Ciruela F.

J Neurochem. 2009 Jun;109(5):1497-507. doi: 10.1111/j.1471-4159.2009.06078.x.

17.

Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.

Canals M, Marcellino D, Fanelli F, Ciruela F, de Benedetti P, Goldberg SR, Neve K, Fuxe K, Agnati LF, Woods AS, Ferré S, Lluis C, Bouvier M, Franco R.

J Biol Chem. 2003 Nov 21;278(47):46741-9.

18.

The importance of the adenosine A(2A) receptor-dopamine D(2) receptor interaction in drug addiction.

Filip M, Zaniewska M, Frankowska M, Wydra K, Fuxe K.

Curr Med Chem. 2012;19(3):317-55. Review.

PMID:
22335511
19.

The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.

Kudlacek O, Just H, Korkhov VM, Vartian N, Klinger M, Pankevych H, Yang Q, Nanoff C, Freissmuth M, Boehm S.

Neuropsychopharmacology. 2003 Jul;28(7):1317-27.

20.

Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats.

O'Neill CE, LeTendre ML, Bachtell RK.

Neuropsychopharmacology. 2012 Apr;37(5):1245-56. doi: 10.1038/npp.2011.312.

Items per page

Supplemental Content

Support Center