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Items: 1 to 20 of 77

1.

Eyeing macular degeneration--few inflammatory remarks.

Rosenbaum JT.

N Engl J Med. 2012 Aug 23;367(8):768-70. doi: 10.1056/NEJMcibr1204973. No abstract available.

PMID:
22913688
2.

Protective inflammasome activation in AMD.

Chen J, Smith LE.

Nat Med. 2012 May 4;18(5):658-60. doi: 10.1038/nm.2761.

3.

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.

Doyle SL, Campbell M, Ozaki E, Salomon RG, Mori A, Kenna PF, Farrar GJ, Kiang AS, Humphries MM, Lavelle EC, O'Neill LA, Hollyfield JG, Humphries P.

Nat Med. 2012 May;18(5):791-8. doi: 10.1038/nm.2717.

4.

NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.

Tseng WA, Thein T, Kinnunen K, Lashkari K, Gregory MS, D'Amore PA, Ksander BR.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):110-20. doi: 10.1167/iovs.12-10655.

5.

The NLRP3 Inflammasome and its Role in Age-Related Macular Degeneration.

Ildefonso CJ, Biswal MR, Ahmed CM, Lewin AS.

Adv Exp Med Biol. 2016;854:59-65. doi: 10.1007/978-3-319-17121-0_9. Review.

PMID:
26427394
6.

NLRP3 inflammasome blockade inhibits VEGF-A-induced age-related macular degeneration.

Marneros AG.

Cell Rep. 2013 Sep 12;4(5):945-58. doi: 10.1016/j.celrep.2013.08.002. Epub 2013 Sep 5.

7.

Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD).

Kauppinen A, Niskanen H, Suuronen T, Kinnunen K, Salminen A, Kaarniranta K.

Immunol Lett. 2012 Sep;147(1-2):29-33. doi: 10.1016/j.imlet.2012.05.005. Epub 2012 Jun 12.

PMID:
22698681
8.

Contribution of the inflammasomes to autoinflammatory diseases and recent mouse models as research tools.

Heymann MC, Rösen-Wolff A.

Clin Immunol. 2013 Jun;147(3):175-84. doi: 10.1016/j.clim.2013.01.006. Epub 2013 Feb 4. Review.

PMID:
23411032
9.

Caspase-4 is required for activation of inflammasomes.

Sollberger G, Strittmatter GE, Kistowska M, French LE, Beer HD.

J Immunol. 2012 Feb 15;188(4):1992-2000. doi: 10.4049/jimmunol.1101620. Epub 2012 Jan 13.

10.

NLRP3 inflammasomes link inflammation and metabolic disease.

De Nardo D, Latz E.

Trends Immunol. 2011 Aug;32(8):373-9. doi: 10.1016/j.it.2011.05.004. Epub 2011 Jul 4. Review.

11.

The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18.

Jha S, Srivastava SY, Brickey WJ, Iocca H, Toews A, Morrison JP, Chen VS, Gris D, Matsushima GK, Ting JP.

J Neurosci. 2010 Nov 24;30(47):15811-20. doi: 10.1523/JNEUROSCI.4088-10.2010.

12.

Clinical strategies for the blockade of IL-18 in inflammatory bowel diseases.

Kanai T, Kamada N, Hisamatsu T.

Curr Drug Targets. 2013 Nov;14(12):1392-9. Review.

PMID:
23651166
13.

The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia.

Witzenrath M, Pache F, Lorenz D, Koppe U, Gutbier B, Tabeling C, Reppe K, Meixenberger K, Dorhoi A, Ma J, Holmes A, Trendelenburg G, Heimesaat MM, Bereswill S, van der Linden M, Tschopp J, Mitchell TJ, Suttorp N, Opitz B.

J Immunol. 2011 Jul 1;187(1):434-40. doi: 10.4049/jimmunol.1003143. Epub 2011 Jun 6.

14.

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction.

Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH.

Nat Immunol. 2012 Jan 29;13(3):255-63. doi: 10.1038/ni.2215.

15.

Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.

Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):127-36. doi: 10.1161/ATVBAHA.114.303763. Epub 2014 Nov 6.

16.

Sensing damage by the NLRP3 inflammasome.

Leemans JC, Cassel SL, Sutterwala FS.

Immunol Rev. 2011 Sep;243(1):152-62. doi: 10.1111/j.1600-065X.2011.01043.x. Review.

17.

The NLRP3 inflammasome: role in airway inflammation.

Im H, Ammit AJ.

Clin Exp Allergy. 2014 Feb;44(2):160-72. doi: 10.1111/cea.12206. Review.

PMID:
24118105
18.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293. Epub 2013 Aug 21.

19.

Uromodulin, inflammasomes, and pyroptosis.

Sanchez-Niño MD, Sanz AB, Ortiz A.

J Am Soc Nephrol. 2012 Nov;23(11):1761-3. doi: 10.1681/ASN.2012090942. Epub 2012 Oct 18. No abstract available.

20.

Metabolic syndrome: is Nlrp3 inflammasome a trigger or a target of insulin resistance?

Mori MA, Bezy O, Kahn CR.

Circ Res. 2011 May 13;108(10):1160-2. doi: 10.1161/RES.0b013e318220b57b. Review. No abstract available. Erratum in: Circ Res. 2011 Jun 24;109(1):e13.

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