Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 94

1.

Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritis.

Minter RR, Cohen ES, Wang B, Liang M, Vainshtein I, Rees G, Eghobamien L, Harrison P, Sims DA, Matthews C, Wilkinson T, Monk P, Drinkwater C, Fabri L, Nash A, McCourt M, Jermutus L, Roskos L, Anderson IK, Sleeman MA.

Br J Pharmacol. 2013 Jan;168(1):200-11. doi: 10.1111/j.1476-5381.2012.02173.x.

2.

Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis.

Greven DE, Cohen ES, Gerlag DM, Campbell J, Woods J, Davis N, van Nieuwenhuijze A, Lewis A, Heasmen S, McCourt M, Corkill D, Dodd A, Elvin J, Statache G, Wicks IP, Anderson IK, Nash A, Sleeman MA, Tak PP.

Ann Rheum Dis. 2015 Oct;74(10):1924-30. doi: 10.1136/annrheumdis-2014-205234. Epub 2014 Jun 16.

3.

In vitro affinity maturation of human GM-CSF antibodies by targeted CDR-diversification.

Steidl S, Ratsch O, Brocks B, Dürr M, Thomassen-Wolf E.

Mol Immunol. 2008 Nov;46(1):135-44. doi: 10.1016/j.molimm.2008.07.013. Epub 2008 Aug 21.

PMID:
18722015
4.

GM-CSF as a therapeutic target in inflammatory diseases.

van Nieuwenhuijze A, Koenders M, Roeleveld D, Sleeman MA, van den Berg W, Wicks IP.

Mol Immunol. 2013 Dec;56(4):675-82. doi: 10.1016/j.molimm.2013.05.002. Epub 2013 Aug 8. Review.

PMID:
23933508
5.

Nonclinical safety of mavrilimumab, an anti-GMCSF receptor alpha monoclonal antibody, in cynomolgus monkeys: relevance for human safety.

Ryan PC, Sleeman MA, Rebelatto M, Wang B, Lu H, Chen X, Wu CY, Hinrichs MJ, Roskos L, Towers H, McKeever K, Dixit R.

Toxicol Appl Pharmacol. 2014 Sep 1;279(2):230-9. doi: 10.1016/j.taap.2014.06.002. Epub 2014 Jun 15.

6.
7.

Targeting GM-CSF in rheumatoid arthritis.

Avci AB, Feist E, Burmester GR.

Clin Exp Rheumatol. 2016 Jul-Aug;34(4 Suppl 98):39-44. Epub 2016 Jul 21. Review.

8.

Mavrilimumab, a human monoclonal GM-CSF receptor-α antibody for the management of rheumatoid arthritis: a novel approach to therapy.

Nair JR, Edwards SW, Moots RJ.

Expert Opin Biol Ther. 2012 Dec;12(12):1661-8. doi: 10.1517/14712598.2012.732062. Epub 2012 Oct 25. Review.

PMID:
23094973
9.

Mechanistic modeling of antigen sink effect for mavrilimumab following intravenous administration in patients with rheumatoid arthritis.

Wang B, Lau YY, Liang M, Vainshtein I, Zusmanovich M, Lu H, Magrini F, Sleeman M, Roskos L.

J Clin Pharmacol. 2012 Aug;52(8):1150-61. doi: 10.1177/0091270011412964. Epub 2011 Sep 23.

PMID:
21947370
10.

Construction and binding kinetics of a soluble granulocyte-macrophage colony-stimulating factor receptor alpha-chain-Fc fusion protein.

Monfardini C, Ramamoorthy M, Rosenbaum H, Fang Q, Godillot PA, Canziani G, Chaiken IM, Williams WV.

J Biol Chem. 1998 Mar 27;273(13):7657-67.

11.

Structure-based design of mimetics for granulocyte-macrophage colony stimulating factor (GM-CSF).

Monfardini C, Canziani G, Plugariu C, Kieber-Emmons T, Godillot AP, Kwah J, Bajgier J, Chaiken I, Williams WV.

Curr Pharm Des. 2002;8(24):2185-99. Review.

PMID:
12369862
12.

Granulocyte-macrophage colony-stimulating factor mimicry and receptor interactions.

Von Feldt JM, Monfardini C, Kieber-Emmons T, Voet D, Weiner DB, Williams WV.

Immunol Res. 1994;13(2-3):96-109.

PMID:
7539825
13.

Multi-response model for rheumatoid arthritis based on delay differential equations in collagen-induced arthritic mice treated with an anti-GM-CSF antibody.

Koch G, Wagner T, Plater-Zyberk C, Lahu G, Schropp J.

J Pharmacokinet Pharmacodyn. 2012 Feb;39(1):55-65. doi: 10.1007/s10928-011-9230-4. Epub 2011 Dec 23.

PMID:
22193331
14.

The structure and dynamics of the granulocyte macrophage colony-stimulating factor receptor defined by the ternary complex model.

Hoang T, De Léan A, Haman A, Beauchemin V, Kitamura T, Clark SC.

J Biol Chem. 1993 Jun 5;268(16):11881-7.

15.

Preclinical studies on synergistic effects of IL-1, IL-3, G-CSF and GM-CSF in cynomolgus monkeys.

Krumwieh D, Weinmann E, Siebold B, Seiler FR.

Int J Cell Cloning. 1990 Jan;8 Suppl 1:229-47; discussion 247-8.

PMID:
1691245
18.

A low affinity chimeric human alpha/beta-granulocyte-macrophage colony-stimulating factor receptor induces ligand-dependent proliferation in a murine cell line.

Eder M, Ernst TJ, Ganser A, Jubinsky PT, Inhorn R, Hoelzer D, Griffin JD.

J Biol Chem. 1994 Dec 2;269(48):30173-80.

20.

In vivo effect of human granulocyte-macrophage colony-stimulating factor (GM-CSF) on neutrophil GM-CSF receptors.

Stacchini A, Fubini L, Gatti E, Mutti L, Piacibello W, Sanavio F, Scagliotti G, Pozzi E, Aglietta M.

Leukemia. 1995 Apr;9(4):665-70.

PMID:
7723402

Supplemental Content

Support Center