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Items: 1 to 20 of 91

1.

Protective effects of an anti-melanocortin-4 receptor scFv derivative in lipopolysaccharide-induced cachexia in rats.

Peter JC, Rossez H, Weckering M, Zipfel G, Lecourt AC, Owen JB, Banks WA, Hofbauer KG.

J Cachexia Sarcopenia Muscle. 2013 Mar;4(1):79-88. doi: 10.1007/s13539-012-0084-4. Epub 2012 Aug 22.

2.

A pharmacologically active monoclonal antibody against the human melanocortin-4 receptor: effectiveness after peripheral and central administration.

Peter JC, Lecourt AC, Weckering M, Zipfel G, Niehoff ML, Banks WA, Hofbauer KG.

J Pharmacol Exp Ther. 2010 May;333(2):478-90. doi: 10.1124/jpet.109.163279. Epub 2010 Jan 29.

3.

Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice.

Weyermann P, Dallmann R, Magyar J, Anklin C, Hufschmid M, Dubach-Powell J, Courdier-Fruh I, Henneböhle M, Nordhoff S, Mondadori C.

PLoS One. 2009;4(3):e4774. doi: 10.1371/journal.pone.0004774. Epub 2009 Mar 19.

4.

Antibodies as pharmacologic tools for studies on the regulation of energy balance.

Hofbauer KG, Lecourt AC, Peter JC.

Nutrition. 2008 Sep;24(9):791-7. doi: 10.1016/j.nut.2008.06.001. Epub 2008 Jul 26.

PMID:
18662861
5.

Differential role of melanocortin receptor subtypes in cachexia.

Marks DL, Butler AA, Turner R, Brookhart G, Cone RD.

Endocrinology. 2003 Apr;144(4):1513-23.

PMID:
12639936
7.

Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure.

Scarlett JM, Bowe DD, Zhu X, Batra AK, Grant WF, Marks DL.

J Endocrinol. 2010 Jul;206(1):121-30. doi: 10.1677/JOE-09-0397. Epub 2010 Apr 6.

8.
9.

Integrative role of neuropeptides and cytokines in cancer anorexia-cachexia syndrome.

Patra SK, Arora S.

Clin Chim Acta. 2012 Jul 11;413(13-14):1025-34. doi: 10.1016/j.cca.2011.12.008. Epub 2012 Jan 11. Review.

PMID:
22251421
10.

Role of the central melanocortin system in cachexia.

Marks DL, Ling N, Cone RD.

Cancer Res. 2001 Feb 15;61(4):1432-8.

11.

Bezafibrate improves bacterial lipopolysaccharide-induced dyslipidemia and anorexia in rats.

Harada N, Kusuyama A, Morishima M, Okada K, Takahashi A, Nakaya Y.

Metabolism. 2007 Apr;56(4):517-22.

PMID:
17379010
12.

Baicalin, a component of Scutellaria baicalensis, alleviates anorexia and inhibits skeletal muscle atrophy in experimental cancer cachexia.

Li B, Wan L, Li Y, Yu Q, Chen P, Gan R, Yang Q, Han Y, Guo C.

Tumour Biol. 2014 Dec;35(12):12415-25. doi: 10.1007/s13277-014-2558-9. Epub 2014 Sep 8.

PMID:
25195133
13.

Pharmacological and pharmacokinetic characterization of 2-piperazine-alpha-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists.

Chen C, Tucci FC, Jiang W, Tran JA, Fleck BA, Hoare SR, Wen J, Chen T, Johns M, Markison S, Foster AC, Marinkovic D, Chen CW, Arellano M, Harman J, Saunders J, Bozigian H, Marks D.

Bioorg Med Chem. 2008 May 15;16(10):5606-18. doi: 10.1016/j.bmc.2008.03.072. Epub 2008 Apr 1.

PMID:
18417348
14.

Update on melanocortin interventions for cachexia: progress toward clinical application.

DeBoer MD.

Nutrition. 2010 Feb;26(2):146-51. doi: 10.1016/j.nut.2009.07.003. Epub 2009 Dec 8. Review.

15.

Neuropeptides in the pathophysiology and treatment of cachexia.

Krasnow SM, Marks DL.

Curr Opin Support Palliat Care. 2010 Dec;4(4):266-71. doi: 10.1097/SPC.0b013e32833e48e7. Review.

16.

Central nervous system mechanisms contributing to the cachexia-anorexia syndrome.

Plata-Salamán CR.

Nutrition. 2000 Oct;16(10):1009-12. Review.

PMID:
11054608
17.

Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice.

Cheung WW, Kuo HJ, Markison S, Chen C, Foster AC, Marks DL, Mak RH.

J Am Soc Nephrol. 2007 Sep;18(9):2517-24. Epub 2007 Aug 8.

18.

Anorexia-cachexia syndrome in pancreatic cancer: recent advances and new pharmacological approach.

Ronga I, Gallucci F, Riccardi F, Uomo G.

Adv Med Sci. 2014 Mar;59(1):1-6. doi: 10.1016/j.advms.2013.11.001. Epub 2014 Mar 15. Review.

19.
20.

Potentiation of ghrelin signaling attenuates cancer anorexia-cachexia and prolongs survival.

Fujitsuka N, Asakawa A, Uezono Y, Minami K, Yamaguchi T, Niijima A, Yada T, Maejima Y, Sedbazar U, Sakai T, Hattori T, Kase Y, Inui A.

Transl Psychiatry. 2011 Jul 26;1:e23. doi: 10.1038/tp.2011.25.

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