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Items: 1 to 20 of 109

1.

Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells.

Kosaka M, Kang MR, Yang G, Li LC.

Nucleic Acid Ther. 2012 Oct;22(5):335-43. doi: 10.1089/nat.2012.0354. Epub 2012 Aug 21.

2.
3.

Intravesical delivery of small activating RNA formulated into lipid nanoparticles inhibits orthotopic bladder tumor growth.

Kang MR, Yang G, Place RF, Charisse K, Epstein-Barash H, Manoharan M, Li LC.

Cancer Res. 2012 Oct 1;72(19):5069-79. doi: 10.1158/0008-5472.CAN-12-1871. Epub 2012 Aug 6.

4.

Antitumor effect of dsRNA-induced p21(WAF1/CIP1) gene activation in human bladder cancer cells.

Chen Z, Place RF, Jia ZJ, Pookot D, Dahiya R, Li LC.

Mol Cancer Ther. 2008 Mar;7(3):698-703. doi: 10.1158/1535-7163.MCT-07-2312.

5.

Anti-cancer effects of p21WAF1/CIP1 transcriptional activation induced by dsRNAs in human hepatocellular carcinoma cell lines.

Wu ZM, Dai C, Huang Y, Zheng CF, Dong QZ, Wang G, Li XW, Zhang XF, Li B, Chen G.

Acta Pharmacol Sin. 2011 Jul;32(7):939-46. doi: 10.1038/aps.2011.28. Epub 2011 Jun 13.

6.

Promoter-associated small double-stranded RNA interacts with heterogeneous nuclear ribonucleoprotein A2/B1 to induce transcriptional activation.

Hu J, Chen Z, Xia D, Wu J, Xu H, Ye ZQ.

Biochem J. 2012 Nov 1;447(3):407-16. doi: 10.1042/BJ20120256.

PMID:
23035981
7.

Targeted p21(WAF1/CIP1) activation by miR-1236 inhibits cell proliferation and correlates with favorable survival in renal cell carcinoma.

Wang C, Tang K, Li Z, Chen Z, Xu H, Ye Z.

Urol Oncol. 2016 Feb;34(2):59.e23-34. doi: 10.1016/j.urolonc.2015.08.014. Epub 2015 Sep 28.

PMID:
26421587
8.

Effects of miR-1236-3p and miR-370-5p on activation of p21 in various tumors and its inhibition on the growth of lung cancer cells.

Li C, Ge Q, Liu J, Zhang Q, Wang C, Cui K, Chen Z.

Tumour Biol. 2017 Jun;39(6):1010428317710824. doi: 10.1177/1010428317710824.

PMID:
28631573
9.

Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells.

Wu HL, Li SM, Hu J, Yu X, Xu H, Chen Z, Ye ZQ.

J Exp Clin Cancer Res. 2016 Sep 17;35(1):145. doi: 10.1186/s13046-016-0423-y.

10.

[Activation of p21(WAF1/CIP1) by small activating RNA inhibits cell proliferation and induces apoptosis in BEL-7402 hepatoma cell].

Wu Z, Huang H, Liu Z, Guo Z, Jiang L, Dong P, Jia G, Chen G.

Zhonghua Yi Xue Za Zhi. 2014 May 27;94(20):1534-8. Chinese.

PMID:
25146739
11.

1,25(OH)2D3 inhibits the progression of hepatocellular carcinoma via downregulating HDAC2 and upregulating P21(WAFI/CIP1).

Huang J, Yang G, Huang Y, Kong W, Zhang S.

Mol Med Rep. 2016 Feb;13(2):1373-80. doi: 10.3892/mmr.2015.4676. Epub 2015 Dec 11.

PMID:
26676829
12.

A New Double Stranded RNA Suppresses Bladder Cancer Development by Upregulating p21 (Waf1/CIP1) Expression.

Wang C, Ge Q, Chen Z, Hu J, Li F, Song X, Xu H, Ye Z.

Biomed Res Int. 2015;2015:304753. doi: 10.1155/2015/304753. Epub 2015 Mar 30.

13.

miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells.

Kang MR, Park KH, Yang JO, Lee CW, Oh SJ, Yun J, Lee MY, Han SB, Kang JS.

PLoS One. 2016 Aug 10;11(8):e0160961. doi: 10.1371/journal.pone.0160961. eCollection 2016.

14.

Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth.

Ren S, Kang MR, Wang J, Huang V, Place RF, Sun Y, Li LC.

Prostate. 2013 Oct;73(14):1591-601. doi: 10.1002/pros.22709. Epub 2013 Jul 8.

PMID:
23836514
15.

p21WAF1/CIP1 gene transcriptional activation exerts cell growth inhibition and enhances chemosensitivity to cisplatin in lung carcinoma cell.

Wei J, Zhao J, Long M, Han Y, Wang X, Lin F, Ren J, He T, Zhang H.

BMC Cancer. 2010 Nov 19;10:632. doi: 10.1186/1471-2407-10-632.

16.

Up-regulation of p21WAF1/CIP1 by small activating RNA inhibits the in vitro and in vivo growth of pancreatic cancer cells.

Zhang Z, Wang Z, Liu X, Wang J, Li F, Li C, Shan B.

Tumori. 2012 Nov;98(6):804-11. doi: 10.1700/1217.13507.

PMID:
23389370
17.

15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE2/PPARĪ³-mediated activation of p21WAF1/Cip1.

Lu D, Han C, Wu T.

Oncogene. 2014 Feb 27;33(9):1101-12. doi: 10.1038/onc.2013.69. Epub 2013 Apr 1. Erratum in: Oncogene. 2014 Oct 9;33(41):4966.

18.

LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.

Liu W, Dai Q, Lu N, Wei L, Ha J, Rong J, Mu R, You Q, Li Z, Guo Q.

Biochem Cell Biol. 2011 Jun;89(3):287-98. doi: 10.1139/O10-162. Epub 2011 Apr 14.

PMID:
21491996
19.

Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase.

Kim H, Kokkotou E, Na X, Rhee SH, Moyer MP, Pothoulakis C, Lamont JT.

Gastroenterology. 2005 Dec;129(6):1875-88.

PMID:
16344056

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