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Items: 1 to 20 of 72

1.

An RNA virus hijacks an incognito function of a DNA repair enzyme.

Virgen-Slane R, Rozovics JM, Fitzgerald KD, Ngo T, Chou W, van der Heden van Noort GJ, Filippov DV, Gershon PD, Semler BL.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14634-9. doi: 10.1073/pnas.1208096109. Epub 2012 Aug 20.

2.

Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections.

Maciejewski S, Nguyen JH, Gómez-Herreros F, Cortés-Ledesma F, Caldecott KW, Semler BL.

MBio. 2015 Dec 29;7(1):e01931-15. doi: 10.1128/mBio.01931-15.

3.

Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity.

Rozovics JM, Virgen-Slane R, Semler BL.

PLoS One. 2011 Mar 7;6(3):e16559. doi: 10.1371/journal.pone.0016559.

4.
5.

Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).

Pommier Y, Huang SY, Gao R, Das BB, Murai J, Marchand C.

DNA Repair (Amst). 2014 Jul;19:114-29. doi: 10.1016/j.dnarep.2014.03.020. Epub 2014 May 22. Review.

6.

Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).

Gao R, Schellenberg MJ, Huang SY, Abdelmalak M, Marchand C, Nitiss KC, Nitiss JL, Williams RS, Pommier Y.

J Biol Chem. 2014 Jun 27;289(26):17960-9. doi: 10.1074/jbc.M114.565374. Epub 2014 May 7.

7.

Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA.

Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL, van Kuppeveld FJ.

Nucleic Acids Res. 2014 Feb;42(4):2473-82. doi: 10.1093/nar/gkt1162. Epub 2013 Nov 15.

8.

Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2.

Marchand C, Abdelmalak M, Kankanala J, Huang SY, Kiselev E, Fesen K, Kurahashi K, Sasanuma H, Takeda S, Aihara H, Wang Z, Pommier Y.

ACS Chem Biol. 2016 Jul 15;11(7):1925-33. doi: 10.1021/acschembio.5b01047. Epub 2016 May 11.

PMID:
27128689
9.

Uridylylation of the potyvirus VPg by viral replicase NIb correlates with the nucleotide binding capacity of VPg.

Puustinen P, Mäkinen K.

J Biol Chem. 2004 Sep 10;279(37):38103-10. Epub 2004 Jun 24.

10.

[Cooperation between picornaviral proteins for the overcoming of cellular protective mechanisms].

Gavriushina ES.

Zh Obshch Biol. 2009 May-Jun;70(3):245-8. Russian.

PMID:
19530601
11.

Novel, structure-based mechanism for uridylylation of the genome-linked peptide (VPg) of picornaviruses.

Schein CH, Volk DE, Oezguen N, Paul A.

Proteins. 2006 Jun 1;63(4):719-26.

PMID:
16498624
12.

Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.

Shi K, Kurahashi K, Gao R, Tsutakawa SE, Tainer JA, Pommier Y, Aihara H.

Nat Struct Mol Biol. 2012 Dec;19(12):1372-7. doi: 10.1038/nsmb.2423. Epub 2012 Oct 28.

13.

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus.

Arias A, Perales C, Escarmís C, Domingo E.

PLoS One. 2010 May 20;5(5):e10735. doi: 10.1371/journal.pone.0010735.

14.

Regulation of picornavirus gene expression.

Bedard KM, Semler BL.

Microbes Infect. 2004 Jun;6(7):702-13. Review.

PMID:
15158778
15.

Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage.

Rao T, Gao R, Takada S, Al Abo M, Chen X, Walters KJ, Pommier Y, Aihara H.

Nucleic Acids Res. 2016 Dec 1;44(21):10201-10215. Epub 2016 Aug 19.

16.

Conservation of RNA-protein interactions among picornaviruses.

Dildine SL, Semler BL.

J Virol. 1992 Jul;66(7):4364-76.

17.

Development of a novel assay for human tyrosyl DNA phosphodiesterase 2.

Adhikari S, Karmahapatra SK, Elias H, Dhopeshwarkar P, Williams RS, Byers S, Uren A, Roy R.

Anal Biochem. 2011 Sep 1;416(1):112-6. doi: 10.1016/j.ab.2011.05.008. Epub 2011 May 12.

18.
19.

Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction.

Adhikari S, Karmahapatra SK, Karve TM, Bandyopadhyay S, Woodrick J, Manthena PV, Glasgow E, Byers S, Saha T, Uren A.

BMC Res Notes. 2012 Mar 9;5:134. doi: 10.1186/1756-0500-5-134.

20.

A picornavirus protein interacts with Ran-GTPase and disrupts nucleocytoplasmic transport.

Porter FW, Bochkov YA, Albee AJ, Wiese C, Palmenberg AC.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12417-22. Epub 2006 Aug 3.

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