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Items: 1 to 20 of 102

1.

Affinity maturation by semi-rational approaches.

Barderas R, Desmet J, Alard P, Casal JI.

Methods Mol Biol. 2012;907:463-86. doi: 10.1007/978-1-61779-974-7_27.

PMID:
22907369
2.

Affinity maturation of antibodies assisted by in silico modeling.

Barderas R, Desmet J, Timmerman P, Meloen R, Casal JI.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9029-34. doi: 10.1073/pnas.0801221105. Epub 2008 Jun 23.

3.

Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.

van den Beucken T, van Neer N, Sablon E, Desmet J, Celis L, Hoogenboom HR, Hufton SE.

J Mol Biol. 2001 Jul 13;310(3):591-601.

PMID:
11439026
4.

Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies.

Wang X, Campoli M, Ko E, Luo W, Ferrone S.

J Immunol Methods. 2004 Nov;294(1-2):23-35.

PMID:
15604013
5.

Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.

Chen Y, Wiesmann C, Fuh G, Li B, Christinger HW, McKay P, de Vos AM, Lowman HB.

J Mol Biol. 1999 Nov 5;293(4):865-81.

PMID:
10543973
6.

Antibody affinity maturation in vitro using unconjugated peptide antigen.

Iwai H, Oztürk B, Ihara M, Ueda H.

Protein Eng Des Sel. 2010 Apr;23(4):185-93. doi: 10.1093/protein/gzp093. Epub 2010 Feb 1.

7.

OptMAVEn--a new framework for the de novo design of antibody variable region models targeting specific antigen epitopes.

Li T, Pantazes RJ, Maranas CD.

PLoS One. 2014 Aug 25;9(8):e105954. doi: 10.1371/journal.pone.0105954. eCollection 2014.

8.

Improving antibody binding affinity and specificity for therapeutic development.

Bostrom J, Lee CV, Haber L, Fuh G.

Methods Mol Biol. 2009;525:353-76, xiii. doi: 10.1007/978-1-59745-554-1_19.

PMID:
19252851
9.

Affinity maturation by phage display.

Thie H, Voedisch B, Dübel S, Hust M, Schirrmann T.

Methods Mol Biol. 2009;525:309-22, xv. doi: 10.1007/978-1-59745-554-1_16.

PMID:
19252854
10.

Selection of non-aggregating VH binders from synthetic VH phage-display libraries.

Arbabi-Ghahroudi M, MacKenzie R, Tanha J.

Methods Mol Biol. 2009;525:187-216, xiii. doi: 10.1007/978-1-59745-554-1_10.

PMID:
19252860
11.

Initial repertoire of anti-(4-hydroxy-3-nitrophenylacetyl) antibodies as potential donors for effective affinity maturation.

Furukawa K, Manabe A, Furukawa A, Kuba H, Okajima T, Azuma T.

Mol Immunol. 2006 Apr;43(11):1751-60. Epub 2006 Jan 9.

PMID:
16406527
12.

Humanization by guided selections.

Kim SJ, Hong HJ.

Methods Mol Biol. 2012;907:247-57. doi: 10.1007/978-1-61779-974-7_14.

PMID:
22907356
13.

Mutual conformational adaptations in antigen and antibody upon complex formation between an Fab and HIV-1 capsid protein p24.

Monaco-Malbet S, Berthet-Colominas C, Novelli A, Battaï N, Piga N, Cheynet V, Mallet F, Cusack S.

Structure. 2000 Oct 15;8(10):1069-77.

14.

In vitro antibody affinity maturation targeting germline hotspots.

Ho M, Pastan I.

Methods Mol Biol. 2009;525:293-308, xiv. doi: 10.1007/978-1-59745-554-1_15.

15.

Stability engineering of antibody single-chain Fv fragments.

Wörn A, Plückthun A.

J Mol Biol. 2001 Feb 2;305(5):989-1010. Review.

PMID:
11162109
16.

Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein.

Pavoni E, Flego M, Dupuis ML, Barca S, Petronzelli F, Anastasi AM, D'Alessio V, Pelliccia A, Vaccaro P, Monteriù G, Ascione A, De Santis R, Felici F, Cianfriglia M, Minenkova O.

BMC Cancer. 2006 Feb 24;6:41.

17.

[Affinity optimization of an anti-hIL17A single-chain Fv antibody through error-prone PCR technique].

Tian H, Bai FL, Xu LM, Wang WF, Niu ZS, Ren GP, Li DS.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2012 Jul;28(7):722-5, 732. Chinese.

PMID:
22768863
18.

Phage versus phagemid libraries for generation of human monoclonal antibodies.

O'Connell D, Becerril B, Roy-Burman A, Daws M, Marks JD.

J Mol Biol. 2002 Aug 2;321(1):49-56.

PMID:
12139932
19.
20.

Interaction between the antigen and antibody is controlled by the constant domains: normal mode dynamics of the HEL-HyHEL-10 complex.

Adachi M, Kurihara Y, Nojima H, Takeda-Shitaka M, Kamiya K, Umeyama H.

Protein Sci. 2003 Oct;12(10):2125-31.

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