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22905857,22905878,23663001,22517103,23772853,26088896,22843280,19243424,24446953,25345628,16847080,21883097,19183227,20299189,25823975,18657175,20132285,31954998,24605793,20944074,29250772,15660766,23480155,17420403,29574701,26088895,24256083,26296511,22372628,22882018,17938371,21451152,15716083,19243423,15699378,24116853,19317886,29653338,27221398,23259931,23179642,19490053,21561392,22871333,25986193,24400691,15144425,19832771,24867391,19001248,16641323,19702752,22512894,22813235,19176965,26724782,25878177,31944276,19222545,28230252,21090838,23837461,25878175,26656783,11564123,25528898,26448264,23287426,15315512,18343174,16884455,20061123,17319919,27521586,26471380,30869165,17681453,23607817,27300147,33340263,17441971,25182978,33681652,32645213,17369059,16393158,26436331,30869168,30267941,16344515,24755135,24962242,26096637,12771254,23362493,11440349,22226572,18077797,20461807,26057204,21090839,31745975,24400692,16678648,31734103,31912493,26414341,23916044,18752932,27869305,28500678,25082395,17635557,21890421,26140524,23918722,27595590,16417534,26370209,24750493,30869167,26700063,24359313,34022524,16990078,35078116,30955420,10908898,11431171,23157581,10881246,10777431,27376872,30560703,11114219,29214650,10612342,25854635,19490035,20345940,21624821,15857429,29784458,23659562,23480153,32673969,24400693,8764816,30897534,10881247,24721197,19016830,25689448,8649570,26526971,36106379,16275822,24621319,24902473,20937567,24785428,27568598,20696552,24902983,12027913,32563171,32409485,20592253,23480154,28575761,11051122,27710868,22304935,27084978,31812902,29030894,11723262,10448830,23490458,35445567,25880756,20113339,23739002,27238234,31462582,25616475,35305446,8956919,8082624,8641230,10227615,29171002,29042752,27265725,32151803,27915111,26506904,9551842,25109239,21775167,25461205,28830031,28236697,25162090,12811359,8649569,14692903,33662894,32717713,16146489,30688135,12837566,36122531,29573400,34657389,11823112,25219353,32622260,32189338,12225311,27669155,26615577,33839450,25288026,23727190,23388853,10563619,24094693,25629136,10999557,12027573,27335114,27038098,34953337,27608437,27566967,28577562,18975234,34033265,24429011,32511754,20089937,18951818,27274257,27589414,29414542,30577702,30062784,21254787,18494791,27613521,16684430,27393930,26111428,25060997,25266613,22771137,29953584,29414548,18660469,10880282,29801910,12972172,33681651,33930626,29369348,31195326,26088886,26763771,16280250,35711112,16893660,10845738,36215830,29197667,21917777,24972948,24915838,35870432,34075567,28005052,29433838,16858958,1416808,24001596,8112232,27055527,22776828,24668240,21917484,28597842,28535410,10078718,16962380,27252470,28236727,32045874,28992560,29486396,24997072,23906691,8404750,21166480,15511696,10845730,8232944,9092954,9443711,17803010,22550979,9092956,25461210,10999555,34951748,22026272,8505632,34942053,34785411,26827266,35802375,23298605,24111974,28638313,36206645,33096456,32119035,29768152,30032806,10768157,22061177,26165169,23883095,9070591,11162750,22902288,31648158,29288911,33621770,29604484,30387043,9674777,21672344,30308428,36176044,7796796,36724644,7641674,17625106,35792849,9152116,9092955,24559052,29127848,27267634,25377429,25941541,24437529,36734057,28741673,1909239,25223728,35453064,9924905,22991134,8469324,31743838,10612357,30047129,31140596,16377140,24203890,32801102,31808053,16948934,27988967,25891931,8325280,35910326,31536041,30001911,23480150,27834088,8559421,32817358,8469323,34741590,31759296,32799941,36150304,22650166,10768304,26575256,11164700,30613951,35777333,28038390,28538134,9008516,26356160,21225020,24415567,19323588,23873520,30424990,12058100,27459034,10227614,26666500,28715780,22917854,30739576,29707476,15511695,30507318,25962657,29527673,28293101,33272774,30169322,34058494,23999191,16800718,11162751,36870093,35499850,28741690,8156959,18301802,25027316,36397377,19170737,24964913,6409599,35910330,35816832,7756713,30525116,28624720,25461214,17888078,26507832,18977587,22633629,25220748,28752473,29194110,26000213,11215835,21673279,31626082,29746395,16804259,28236698,33940525,8089668,25495693,22845761,31035242,29213041,29704679,26316718,34427754,27935018,34633084,1944909,31576134,28522077,32447055,28511603,32524053,23636029,23294191,32396252,33592505,36063589,23368799,28737479,35175622,33171342,26911639,29588976,35820301,28492978,31371205,23717043,1483856,24400689,22242805,33998885,24911669,34526963,30799639,25044045,34864380,25616485,15740180,23106523,36263757,34782307,28703720,22902287,34191081,24621228,6357772,28552718,21269281,37011526,10714402,27271515,28568478,35605481,26133811,22708259,25474187,29870595,8112231,25227593,21584739,31937512,35705501,32285623,28394442,27753779,23480149,29159466,31638579,33866126,8559420,34730518,31901668,32782230,22428181,35168142,25730374,23365066,8058148,6403342,2496577,36268811,28566726,35770768,24662975,16722786,27688936,21936589,33972334,1909240,36327645,30726628,27389600,31026743,29204953,33602660,31538659,8751028,32623899,10082251,22061178,28166365,26525618,32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Results by year

Year	Number of Results
1976	1
1980	1
1981	1
1983	3
1984	2
1985	1
1987	1
1989	1
1991	4
1992	2
1993	6
1994	6
1995	4
1996	7
1997	7
1998	3
1999	10
2000	20
2001	9
2002	6
2003	4
2004	6
2005	12
2006	15
2007	11
2008	14
2009	17
2010	15
2011	20
2012	37
2013	52
2014	61
2015	50
2016	52
2017	60
2018	53
2019	50
2020	57
2021	59
2022	53
2023	12
2024	0

716 results

Page of 72

Results by year

Page 1

Evaluation of adjunctive perampanel in patients with refractory partial-onset seizures: results of randomized global phase III study 305.

French JA, Krauss GL, Steinhoff BJ, Squillacote D, Yang H, Kumar D, Laurenza A. French JA, et al. Epilepsia. 2013 Jan;54(1):117-25. doi: 10.1111/j.1528-1167.2012.03638.x. Epub 2012 Aug 20. Epilepsia. 2013. PMID: 22905857 Free article. Clinical Trial.

Perampanel, a selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, as adjunctive therapy for refractory partial-onset seizures: interim results from phase III, extension study 307.

Krauss GL, Perucca E, Ben-Menachem E, Kwan P, Shih JJ, Squillacote D, Yang H, Gee M, Zhu J, Laurenza A. Krauss GL, et al. Epilepsia. 2013 Jan;54(1):126-34. doi: 10.1111/j.1528-1167.2012.03648.x. Epub 2012 Aug 20. Epilepsia. 2013. PMID: 22905878 Free article. Clinical Trial.

Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: a pooled analysis of three phase III studies.

Steinhoff BJ, Ben-Menachem E, Ryvlin P, Shorvon S, Kramer L, Satlin A, Squillacote D, Yang H, Zhu J, Laurenza A. Steinhoff BJ, et al. Epilepsia. 2013 Aug;54(8):1481-9. doi: 10.1111/epi.12212. Epub 2013 May 10. Epilepsia. 2013. PMID: 23663001 Free article. Clinical Trial.

Randomized phase III study 306: adjunctive perampanel for refractory partial-onset seizures.

Krauss GL, Serratosa JM, Villanueva V, Endziniene M, Hong Z, French J, Yang H, Squillacote D, Edwards HB, Zhu J, Laurenza A. Krauss GL, et al. Neurology. 2012 May 1;78(18):1408-15. doi: 10.1212/WNL.0b013e318254473a. Epub 2012 Apr 18. Neurology. 2012. PMID: 22517103 Clinical Trial.

Concentration-effect relationships with perampanel in patients with pharmacoresistant partial-onset seizures.

Gidal BE, Ferry J, Majid O, Hussein Z. Gidal BE, et al. Epilepsia. 2013 Aug;54(8):1490-7. doi: 10.1111/epi.12240. Epub 2013 Jun 17. Epilepsia. 2013. PMID: 23772853 Free article. Clinical Trial.

Efficacy and safety of perampanel in patients with drug-resistant partial seizures after conversion from double-blind placebo to open-label perampanel.

Montouris G, Yang H, Williams B, Zhou S, Laurenza A, Fain R. Montouris G, et al. Epilepsy Res. 2015 Aug;114:131-40. doi: 10.1016/j.eplepsyres.2015.04.011. Epub 2015 May 1. Epilepsy Res. 2015. PMID: 26088896 Free article. Clinical Trial.

Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304.

French JA, Krauss GL, Biton V, Squillacote D, Yang H, Laurenza A, Kumar D, Rogawski MA. French JA, et al. Neurology. 2012 Aug 7;79(6):589-96. doi: 10.1212/WNL.0b013e3182635735. Epub 2012 Jul 25. Neurology. 2012. PMID: 22843280 Free PMC article. Clinical Trial.

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study.

Elger C, Halász P, Maia J, Almeida L, Soares-da-Silva P; BIA-2093-301 Investigators Study Group. Elger C, et al. Epilepsia. 2009 Mar;50(3):454-63. doi: 10.1111/j.1528-1167.2008.01946.x. Epub 2009 Feb 21. Epilepsia. 2009. PMID: 19243424 Free article. Clinical Trial.

Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double-blind, placebo-controlled trial.

Biton V, Berkovic SF, Abou-Khalil B, Sperling MR, Johnson ME, Lu S. Biton V, et al. Epilepsia. 2014 Jan;55(1):57-66. doi: 10.1111/epi.12433. Epub 2013 Nov 8. Epilepsia. 2014. PMID: 24446953 Free article. Clinical Trial.

[Perampanel in treatment of refractory partial epilepsy in adolescents and adults: results of international multicenter randomized, double-blind, placebo-controlled phase III studies].

Belousova ED. Belousova ED. Zh Nevrol Psikhiatr Im S S Korsakova. 2014;114(8):32-8. Zh Nevrol Psikhiatr Im S S Korsakova. 2014. PMID: 25345628 Clinical Trial. Russian.

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