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Items: 1 to 20 of 107


Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.

Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R, Williams RW, Schughart K.

BMC Genomics. 2012 Aug 20;13:411. doi: 10.1186/1471-2164-13-411.


Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice.

Boon AC, deBeauchamp J, Hollmann A, Luke J, Kotb M, Rowe S, Finkelstein D, Neale G, Lu L, Williams RW, Webby RJ.

J Virol. 2009 Oct;83(20):10417-26. doi: 10.1128/JVI.00514-09. Epub 2009 Aug 12.


Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.

Shin DL, Hatesuer B, Bergmann S, Nedelko T, Schughart K.

J Virol. 2015 Oct;89(19):9998-10009. doi: 10.1128/JVI.01305-15. Epub 2015 Jul 22.


Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection.

Bahgat MM, Błazejewska P, Schughart K.

Virol J. 2011 Jan 20;8:27. doi: 10.1186/1743-422X-8-27.


RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection.

Wilk E, Pandey AK, Leist SR, Hatesuer B, Preusse M, Pommerenke C, Wang J, Schughart K.

BMC Genomics. 2015 Sep 2;16:655. doi: 10.1186/s12864-015-1867-8.


Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

Leist SR, Pilzner C, van den Brand JM, Dengler L, Geffers R, Kuiken T, Balling R, Kollmus H, Schughart K.

BMC Genomics. 2016 Feb 27;17:143. doi: 10.1186/s12864-016-2483-y.


Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains.

Preusse M, Schughart K, Wilk E, Klawonn F, Pessler F.

BMC Res Notes. 2015 Jun 6;8:225. doi: 10.1186/s13104-015-1195-8.


Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.

Leist SR, Kollmus H, Hatesuer B, Lambertz RL, Schughart K.

Virol J. 2016 Jan 27;13:17. doi: 10.1186/s12985-016-0471-0.


Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection.

Alberts R, Srivastava B, Wu H, Viegas N, Geffers R, Klawonn F, Novoselova N, do Valle TZ, Panthier JJ, Schughart K.

Microbes Infect. 2010 Apr;12(4):309-18. doi: 10.1016/j.micinf.2010.01.008. Epub 2010 Jan 28.


Host genetic background strongly influences the response to influenza a virus infections.

Srivastava B, Błazejewska P, Hessmann M, Bruder D, Geffers R, Mauel S, Gruber AD, Schughart K.

PLoS One. 2009;4(3):e4857. doi: 10.1371/journal.pone.0004857. Epub 2009 Mar 18.


A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice.

Boon AC, Williams RW, Sinasac DS, Webby RJ.

BMC Genomics. 2014 Nov 24;15:1017. doi: 10.1186/1471-2164-15-1017.


Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice.

Preusse M, Tantawy MA, Klawonn F, Schughart K, Pessler F.

BMC Microbiol. 2013 Dec 17;13:293. doi: 10.1186/1471-2180-13-293.


Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection.

Dengler L, May M, Wilk E, Bahgat MM, Schughart K.

Virol J. 2012 Sep 19;9:212. doi: 10.1186/1743-422X-9-212.


Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice.

Russo LM, Abdeltawab NF, O'Brien AD, Kotb M, Melton-Celsa AR.

BMC Genomics. 2015 Nov 16;16:947. doi: 10.1186/s12864-015-2127-7.


Hyporeactivity of Alveolar Macrophages and Higher Respiratory Cell Permissivity Characterize DBA/2J Mice Infected by Influenza A Virus.

Casanova T, Van de Paar E, Desmecht D, Garigliany MM.

J Interferon Cytokine Res. 2015 Oct;35(10):808-20. doi: 10.1089/jir.2014.0237. Epub 2015 Jul 2.


A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice.

Thompson RL, Williams RW, Kotb M, Sawtell NM.

PLoS One. 2014 Mar 20;9(3):e92342. doi: 10.1371/journal.pone.0092342. eCollection 2014.


Multigenic control and sex bias in host susceptibility to spore-induced pulmonary anthrax in mice.

Yadav JS, Pradhan S, Kapoor R, Bangar H, Burzynski BB, Prows DR, Levin L.

Infect Immun. 2011 Aug;79(8):3204-15. doi: 10.1128/IAI.01389-10. Epub 2011 May 31.


Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT.

PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28.


Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight.

Lu L, Wei L, Peirce JL, Wang X, Zhou J, Homayouni R, Williams RW, Airey DC.

BMC Genomics. 2008 Sep 25;9:444. doi: 10.1186/1471-2164-9-444.


2009 pandemic H1N1 influenza A virus strains display differential pathogenicity in C57BL/6J but not BALB/c mice.

Otte A, Gabriel G.

Virulence. 2011 Nov-Dec;2(6):563-6. doi: 10.4161/viru.2.6.18148. Epub 2011 Nov 1.


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