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Items: 1 to 20 of 100

1.

Recovery of phenotypes obtained by adaptive evolution through inverse metabolic engineering.

Hong KK, Nielsen J.

Appl Environ Microbiol. 2012 Nov;78(21):7579-86. doi: 10.1128/AEM.01444-12. Epub 2012 Aug 17.

2.

Unravelling evolutionary strategies of yeast for improving galactose utilization through integrated systems level analysis.

Hong KK, Vongsangnak W, Vemuri GN, Nielsen J.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12179-84. doi: 10.1073/pnas.1103219108. Epub 2011 Jun 29.

3.

Adaptively evolved yeast mutants on galactose show trade-offs in carbon utilization on glucose.

Hong KK, Nielsen J.

Metab Eng. 2013 Mar;16:78-86. doi: 10.1016/j.ymben.2013.01.007. Epub 2013 Jan 29.

PMID:
23376593
4.

Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications.

Otero JM, Vongsangnak W, Asadollahi MA, Olivares-Hernandes R, Maury J, Farinelli L, Barlocher L, Osterås M, Schalk M, Clark A, Nielsen J.

BMC Genomics. 2010 Dec 22;11:723. doi: 10.1186/1471-2164-11-723.

5.

Rapid and efficient galactose fermentation by engineered Saccharomyces cerevisiae.

Quarterman J, Skerker JM, Feng X, Liu IY, Zhao H, Arkin AP, Jin YS.

J Biotechnol. 2016 Jul 10;229:13-21. doi: 10.1016/j.jbiotec.2016.04.041. Epub 2016 Apr 30.

PMID:
27140870
6.

Yeast mutants temperature-sensitive for growth after random mutagenesis of the chromosomal RAS2 gene and deletion of the RAS1 gene.

Fasano O, Crechet JB, De Vendittis E, Zahn R, Feger G, Vitelli A, Parmeggiani A.

EMBO J. 1988 Nov;7(11):3375-83.

7.
8.

Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering.

Lee KS, Hong ME, Jung SC, Ha SJ, Yu BJ, Koo HM, Park SM, Seo JH, Kweon DH, Park JC, Jin YS.

Biotechnol Bioeng. 2011 Mar;108(3):621-31. doi: 10.1002/bit.22988. Epub 2010 Nov 12.

PMID:
21246509
9.

Metabolic engineering of a Saccharomyces cerevisiae strain capable of simultaneously utilizing glucose and galactose to produce enantiopure (2R,3R)-butanediol.

Lian J, Chao R, Zhao H.

Metab Eng. 2014 May;23:92-9. doi: 10.1016/j.ymben.2014.02.003. Epub 2014 Feb 10.

PMID:
24525332
10.
12.
13.

PGM2 overexpression improves anaerobic galactose fermentation in Saccharomyces cerevisiae.

Garcia Sanchez R, Hahn-Hägerdal B, Gorwa-Grauslund MF.

Microb Cell Fact. 2010 May 27;9:40. doi: 10.1186/1475-2859-9-40.

14.

Laboratory Evolution of a Biotin-Requiring Saccharomyces cerevisiae Strain for Full Biotin Prototrophy and Identification of Causal Mutations.

Bracher JM, de Hulster E, Koster CC, van den Broek M, Daran JG, van Maris AJA, Pronk JT.

Appl Environ Microbiol. 2017 Aug 1;83(16). pii: e00892-17. doi: 10.1128/AEM.00892-17. Print 2017 Aug 15.

PMID:
28600311
15.

Ras mutants enhance the ability of cells to anticipate future lethal stressors.

Zacharioudakis I, Papagiannidis D, Gounalaki N, Stratidaki I, Kafetzopoulos D, Tzamarias D.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):1278-1283. doi: 10.1016/j.bbrc.2016.12.028. Epub 2016 Dec 7.

PMID:
27939892
16.

Ras-pathway has a dual role in yeast galactose metabolism.

Mirisola MG, Gallo A, De Leo G.

FEBS Lett. 2007 May 15;581(10):2009-16. Epub 2007 Apr 23.

17.

Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae.

Oud B, Guadalupe-Medina V, Nijkamp JF, de Ridder D, Pronk JT, van Maris AJ, Daran JM.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4223-31. doi: 10.1073/pnas.1305949110. Epub 2013 Oct 21.

18.

Biochemical characterization of yeast RAS2 mutants reveals a new region of ras protein involved in the interaction with GTPase-activating proteins.

Wood DR, Poullet P, Wilson BA, Khalil M, Tanaka K, Cannon JF, Tamanoi F.

J Biol Chem. 1994 Feb 18;269(7):5322-7.

19.

A polybasic domain allows nonprenylated Ras proteins to function in Saccharomyces cerevisiae.

Mitchell DA, Farh L, Marshall TK, Deschenes RJ.

J Biol Chem. 1994 Aug 26;269(34):21540-6.

20.

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