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Items: 1 to 20 of 69

1.

The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.

Gao H, Chakraborty G, Lee-Lim AP, Mo Q, Decker M, Vonica A, Shen R, Brogi E, Brivanlou AH, Giancotti FG.

Cell. 2012 Aug 17;150(4):764-79. doi: 10.1016/j.cell.2012.06.035. Erratum in: Cell. 2012 Dec 7;151(6):1386-8.

2.

BMP/Coco antagonism as a deterministic factor of metastasis dormancy in lung.

Martinez J, Zhang XH.

Breast Cancer Res. 2013 Jan 15;15(1):302. doi: 10.1186/bcr3350.

3.

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4.

Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, Gomis RR, Massagué J.

Cell. 2008 Apr 4;133(1):66-77. doi: 10.1016/j.cell.2008.01.046.

4.

Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung.

Koli K, Wempe F, Sterner-Kock A, Kantola A, Komor M, Hofmann WK, von Melchner H, Keski-Oja J.

J Cell Biol. 2004 Oct 11;167(1):123-33. Epub 2004 Oct 4.

5.

Engagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signaling.

Zhang H, Meng F, Wu S, Kreike B, Sethi S, Chen W, Miller FR, Wu G.

Cancer Res. 2011 Jul 15;71(14):4846-56. doi: 10.1158/0008-5472.CAN-11-0414. Epub 2011 Jul 12.

6.

Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling.

Gao H, Chakraborty G, Zhang Z, Akalay I, Gadiya M, Gao Y, Sinha S, Hu J, Jiang C, Akram M, Brogi E, Leitinger B, Giancotti FG.

Cell. 2016 Jun 30;166(1):47-62. doi: 10.1016/j.cell.2016.06.009.

7.

Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation.

Gao H, Chakraborty G, Lee-Lim AP, Mavrakis KJ, Wendel HG, Giancotti FG.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16532-7. doi: 10.1073/pnas.1403234111. Epub 2014 Nov 5.

8.

Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.

Katsuno Y, Hanyu A, Kanda H, Ishikawa Y, Akiyama F, Iwase T, Ogata E, Ehata S, Miyazono K, Imamura T.

Oncogene. 2008 Oct 23;27(49):6322-33. doi: 10.1038/onc.2008.232. Epub 2008 Jul 28.

PMID:
18663362
9.

Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling.

Zhou S, Flamier A, Abdouh M, Tétreault N, Barabino A, Wadhwa S, Bernier G.

Development. 2015 Oct 1;142(19):3294-306. doi: 10.1242/dev.125385.

10.

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors.

Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massagué J.

J Clin Invest. 2005 Jan;115(1):44-55.

11.

Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma.

Wordinger RJ, Fleenor DL, Hellberg PE, Pang IH, Tovar TO, Zode GS, Fuller JA, Clark AF.

Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1191-200.

PMID:
17325163
12.

A six-gene signature predicting breast cancer lung metastasis.

Landemaine T, Jackson A, Bellahcène A, Rucci N, Sin S, Abad BM, Sierra A, Boudinet A, Guinebretière JM, Ricevuto E, Noguès C, Briffod M, Bièche I, Cherel P, Garcia T, Castronovo V, Teti A, Lidereau R, Driouch K.

Cancer Res. 2008 Aug 1;68(15):6092-9. doi: 10.1158/0008-5472.CAN-08-0436.

13.

Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells.

Luo Q, Kang Q, Si W, Jiang W, Park JK, Peng Y, Li X, Luu HH, Luo J, Montag AG, Haydon RC, He TC.

J Biol Chem. 2004 Dec 31;279(53):55958-68. Epub 2004 Oct 20.

14.

BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression.

Naber HP, Wiercinska E, Pardali E, van Laar T, Nirmala E, Sundqvist A, van Dam H, van der Horst G, van der Pluijm G, Heckmann B, Danen EH, Ten Dijke P.

Cell Oncol (Dordr). 2012 Feb;35(1):19-28. doi: 10.1007/s13402-011-0058-0. Epub 2011 Sep 21.

15.

An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.

Park CY, Min KN, Son JY, Park SY, Nam JS, Kim DK, Sheen YY.

Cancer Lett. 2014 Aug 28;351(1):72-80. doi: 10.1016/j.canlet.2014.05.006. Epub 2014 Jun 2.

PMID:
24887560
16.

Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer.

Walser TC, Rifat S, Ma X, Kundu N, Ward C, Goloubeva O, Johnson MG, Medina JC, Collins TL, Fulton AM.

Cancer Res. 2006 Aug 1;66(15):7701-7.

17.

Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers.

Wendt MK, Taylor MA, Schiemann BJ, Sossey-Alaoui K, Schiemann WP.

Breast Cancer Res. 2014 Mar 11;16(2):R24. doi: 10.1186/bcr3623.

18.

The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells.

Langenfeld EM, Calvano SE, Abou-Nukta F, Lowry SF, Amenta P, Langenfeld J.

Carcinogenesis. 2003 Sep;24(9):1445-54. Epub 2003 Jun 19.

PMID:
12819188
19.

Vascular endothelial growth factor plays a critical role in the formation of the pre-metastatic niche via prostaglandin E2.

Liu S, Jiang M, Zhao Q, Li S, Peng Y, Zhang P, Han M.

Oncol Rep. 2014 Dec;32(6):2477-84. doi: 10.3892/or.2014.3516. Epub 2014 Sep 24.

PMID:
25333935
20.

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model.

Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, Yang YA, Wakefield LM, Tomonaga T.

PLoS One. 2015 May 18;10(5):e0126483. doi: 10.1371/journal.pone.0126483. eCollection 2015.

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