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Items: 1 to 20 of 95

1.

Assessment of metabolic stability using the rainbow trout (Oncorhynchus mykiss) liver S9 fraction.

Johanning K, Hancock G, Escher B, Adekola A, Bernhard MJ, Cowan-Ellsberry C, Domoradzki J, Dyer S, Eickhoff C, Embry M, Erhardt S, Fitzsimmons P, Halder M, Hill J, Holden D, Johnson R, Rutishauser S, Segner H, Schultz I, Nichols J.

Curr Protoc Toxicol. 2012 Aug;Chapter 14:Unit 14.10.1-28. doi: 10.1002/0471140856.tx1410s53.

PMID:
22896006
2.

Determination of Metabolic Stability Using Cryopreserved Hepatocytes from Rainbow Trout (Oncorhynchus mykiss).

Fay KA, Nabb DL, Mingoia RT, Bischof I, Nichols JW, Segner H, Johanning K, Han X.

Curr Protoc Toxicol. 2015 Aug 6;65:4.42.1-29. doi: 10.1002/0471140856.tx0442s65.

PMID:
26250400
3.
4.

Phase I metabolism of 3-methylindole, an environmental pollutant, by hepatic microsomes from carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss).

Zlabek V, Burkina V, Borrisser-Pairó F, Sakalli S, Zamaratskaia G.

Chemosphere. 2016 May;150:304-310. doi: 10.1016/j.chemosphere.2016.02.037. Epub 2016 Feb 23.

PMID:
26915592
5.

Rainbow trout primary epidermal cell proliferation as an indicator of aquatic toxicity: an in vitro/in vivo exposure comparison.

Kilemade M, Lyons-Alcantara M, Rose T, Fitzgerald R, Mothersill C.

Aquat Toxicol. 2002 Oct 2;60(1-2):43-59.

PMID:
12204586
6.

Comparative pharmaceutical metabolism by rainbow trout (Oncorhynchus mykiss) liver S9 fractions.

Connors KA, Du B, Fitzsimmons PN, Hoffman AD, Chambliss CK, Nichols JW, Brooks BW.

Environ Toxicol Chem. 2013 Aug;32(8):1810-8. doi: 10.1002/etc.2240. Epub 2013 Jun 21.

PMID:
23606059
7.

Interactions of pharmaceuticals and other xenobiotics on hepatic pregnane X receptor and cytochrome P450 3A signaling pathway in rainbow trout (Oncorhynchus mykiss).

Wassmur B, Gräns J, Kling P, Celander MC.

Aquat Toxicol. 2010 Oct 1;100(1):91-100. doi: 10.1016/j.aquatox.2010.07.013. Epub 2010 Jul 17.

PMID:
20719396
8.

Influence of cyanobacteria on water activity and dry matter of muscles in the common carp (Cyprinus carpio L.) and rainbow trout (Oncorhynchus mykiss W.).

Navratil L, Vlasek V, Langova J, Palikova M, Brabec T, Mares J, Kopp R, Klima Z, Navratil S.

Neuro Endocrinol Lett. 2012;33 Suppl 3:120-3.

PMID:
23353854
9.

Subcellular differences in handling Cu excess in three freshwater fish species contributes greatly to their differences in sensitivity to Cu.

Eyckmans M, Blust R, De Boeck G.

Aquat Toxicol. 2012 Aug 15;118-119:97-107. doi: 10.1016/j.aquatox.2012.03.019. Epub 2012 Apr 10.

PMID:
22542735
10.

Toxic effects of orimulsion on rainbow trout Oncorhynchus mykiss.

Svecevicius G, Kazlauskiene N, Vosyliene MZ.

Environ Sci Pollut Res Int. 2003;10(5):281-3.

PMID:
14535640
13.

Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Oncorhynchus mykiss) hepatocytes.

Gagné F, Blaise C, André C.

Ecotoxicol Environ Saf. 2006 Jul;64(3):329-36. Epub 2005 May 31.

PMID:
15923035
14.

Enantiomer-specific in vitro biotransformation of select pharmaceuticals in rainbow trout (Oncorhynchus mykiss).

Connors KA, Du B, Fitzsimmons PN, Chambliss CK, Nichols JW, Brooks BW.

Chirality. 2013 Nov;25(11):763-7. doi: 10.1002/chir.22211. Epub 2013 Jul 29.

PMID:
23893772
15.

Hepatic clearance of 6 polycyclic aromatic hydrocarbons by isolated perfused trout livers: prediction from in vitro clearance by liver S9 fractions.

Nichols JW, Hoffman AD, ter Laak TL, Fitzsimmons PN.

Toxicol Sci. 2013 Dec;136(2):359-72. doi: 10.1093/toxsci/kft219. Epub 2013 Oct 4.

PMID:
24097670
16.
17.

Protein and lipid binding parameters in rainbow trout (Oncorhynchus mykiss) blood and liver fractions to extrapolate from an in vitro metabolic degradation assay to in vivo bioaccumulation potential of hydrophobic organic chemicals.

Escher BI, Cowan-Ellsberry CE, Dyer S, Embry MR, Erhardt S, Halder M, Kwon JH, Johanning K, Oosterwijk MT, Rutishauser S, Segner H, Nichols J.

Chem Res Toxicol. 2011 Jul 18;24(7):1134-43. doi: 10.1021/tx200114y. Epub 2011 Jun 8.

PMID:
21604782
18.

Ibuprofen metabolism in the liver and gill of rainbow trout, Oncorhynchus mykiss.

Gomez CF, Constantine L, Moen M, Vaz A, Wang W, Huggett DB.

Bull Environ Contam Toxicol. 2011 Mar;86(3):247-51. doi: 10.1007/s00128-011-0200-8. Epub 2011 Feb 8.

PMID:
21301807
19.

The integration of in vivo and in vitro metabolism assays to investigate the stereoselective behaviors of benalaxyl in rainbow trout (Oncorhynchus mykiss).

Gu X, Yao T.

J Environ Sci Health B. 2013;48(8):693-9. doi: 10.1080/03601234.2013.778631. Erratum in: J Environ Sci Health B. 2013;48(12):1121.

PMID:
23638897
20.

In vivo and in vitro debromination of decabromodiphenyl ether (BDE 209) by juvenile rainbow trout and common carp.

Stapleton HM, Brazil B, Holbrook RD, Mitchelmore CL, Benedict R, Konstantinov A, Potter D.

Environ Sci Technol. 2006 Aug 1;40(15):4653-8.

PMID:
16913120

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