Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 103

1.

Regulation of metastasis; mitochondrial DNA mutations have appeared on stage.

Ishikawa K, Imanishi H, Takenaga K, Hayashi J.

J Bioenerg Biomembr. 2012 Dec;44(6):639-44. doi: 10.1007/s10863-012-9468-6. Review.

PMID:
22895836
2.

Reversible regulation of metastasis by ROS-generating mtDNA mutations.

Ishikawa K, Koshikawa N, Takenaga K, Nakada K, Hayashi J.

Mitochondrion. 2008 Sep;8(4):339-44. doi: 10.1016/j.mito.2008.07.006. Epub 2008 Aug 8. Review.

PMID:
18727959
3.

A novel function of mtDNA: its involvement in metastasis.

Ishikawa K, Hayashi J.

Ann N Y Acad Sci. 2010 Jul;1201:40-3. doi: 10.1111/j.1749-6632.2010.05616.x. Review.

PMID:
20649537
4.

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.

Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J.

Science. 2008 May 2;320(5876):661-4. doi: 10.1126/science.1156906. Epub 2008 Apr 3.

5.

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.

Park JS, Sharma LK, Li H, Xiang R, Holstein D, Wu J, Lechleiter J, Naylor SL, Deng JJ, Lu J, Bai Y.

Hum Mol Genet. 2009 May 1;18(9):1578-89. doi: 10.1093/hmg/ddp069. Epub 2009 Feb 10.

6.

Mitochondrial DNA mutations regulate metastasis of human breast cancer cells.

Imanishi H, Hattori K, Wada R, Ishikawa K, Fukuda S, Takenaga K, Nakada K, Hayashi J.

PLoS One. 2011;6(8):e23401. doi: 10.1371/journal.pone.0023401. Epub 2011 Aug 11.

7.

Free radicals-mediated damage in transmitochondrial cells harboring the T14487C mutation in the ND6 gene of mtDNA.

Gonzalo R, Garcia-Arumi E, Llige D, Marti R, Solano A, Montoya J, Arenas J, Andreu AL.

FEBS Lett. 2005 Dec 19;579(30):6909-13. Epub 2005 Dec 1.

8.

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis.

Ishikawa K, Hashizume O, Koshikawa N, Fukuda S, Nakada K, Takenaga K, Hayashi J.

FEBS Lett. 2008 Oct 15;582(23-24):3525-30. doi: 10.1016/j.febslet.2008.09.024. Epub 2008 Sep 19.

9.

Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system.

Imanishi H, Takibuchi G, Kobayashi T, Ishikawa K, Nakada K, Mori M, Kikkawa Y, Takenaga K, Toyama-Sorimachi N, Hayashi J.

PLoS One. 2013 Sep 30;8(9):e75981. doi: 10.1371/journal.pone.0075981. eCollection 2013.

10.

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development.

Hashizume O, Shimizu A, Yokota M, Sugiyama A, Nakada K, Miyoshi H, Itami M, Ohira M, Nagase H, Takenaga K, Hayashi J.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10528-33. doi: 10.1073/pnas.1202367109. Epub 2012 Jun 11.

11.

"ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis"--a critical commentary.

Zielonka J, Kalyanaraman B.

Free Radic Biol Med. 2008 Nov 1;45(9):1217-9. doi: 10.1016/j.freeradbiomed.2008.07.025. Epub 2008 Aug 23.

12.

Mutations in mitochondrial DNA regulate mitochondrial diseases and metastasis but do not regulate aging.

Hayashi JI, Hashizume O, Ishikawa K, Shimizu A.

Curr Opin Genet Dev. 2016 Jun;38:63-67. doi: 10.1016/j.gde.2016.03.004. Epub 2016 Apr 11. Review.

PMID:
27078865
13.

Administration of an antioxidant prevents lymphoma development in transmitochondrial mice overproducing reactive oxygen species.

Yamanashi H, Hashizume O, Yonekawa H, Nakada K, Hayashi J.

Exp Anim. 2014;63(4):459-66. Epub 2014 Jul 22.

14.

Trading mtDNA uncovers its role in metastasis.

Ishikawa K, Hayashi J.

Cell Adh Migr. 2009 Jan-Mar;3(1):11-3. Epub 2009 Jan 21.

15.

Cancer cell mitochondria confer apoptosis resistance and promote metastasis.

Kulawiec M, Owens KM, Singh KK.

Cancer Biol Ther. 2009 Jul;8(14):1378-85. Epub 2009 Jul 16.

PMID:
19556849
16.

Part II. Mitochondrial mutational status of high nitric oxide adapted cell line BT-20 (BT-20-HNO) as it relates to human primary breast tumors.

De Vitto H, Mendonça BS, Elseth KM, Vesper BJ, Portari EA, Gallo CV, Paradise WA, Rumjanek FD, Radosevich JA.

Tumour Biol. 2013 Feb;34(1):337-47. doi: 10.1007/s13277-012-0555-4. Epub 2012 Dec 14.

PMID:
23238816
17.

Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with Keratoconus.

Hao XD, Chen ZL, Qu ML, Zhao XW, Li SX, Chen P.

PLoS One. 2016 Oct 26;11(10):e0165580. doi: 10.1371/journal.pone.0165580. eCollection 2016.

18.
19.

Generation of mtDNA-exchanged cybrids for determination of the effects of mtDNA mutations on tumor phenotypes.

Ishikawa K, Hayashi J.

Methods Enzymol. 2009;457:335-46. doi: 10.1016/S0076-6879(09)05019-8.

PMID:
19426877
20.

Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells.

Yokota M, Shitara H, Hashizume O, Ishikawa K, Nakada K, Ishii R, Taya C, Takenaga K, Yonekawa H, Hayashi J.

FEBS Lett. 2010 Sep 24;584(18):3943-8. doi: 10.1016/j.febslet.2010.07.048. Epub 2010 Aug 3.

Supplemental Content

Support Center