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Comparison of gene transfer to the murine liver following intraperitoneal and intraportal delivery of hepatotropic AAV pseudo-serotypes.

Dane AP, Wowro SJ, Cunningham SC, Alexander IE.

Gene Ther. 2013 Apr;20(4):460-4. doi: 10.1038/gt.2012.67. Epub 2012 Aug 16.


Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors.

Müller OJ, Leuchs B, Pleger ST, Grimm D, Franz WM, Katus HA, Kleinschmidt JA.

Cardiovasc Res. 2006 Apr 1;70(1):70-8. Epub 2006 Jan 31.


Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo.

Michelfelder S, Varadi K, Raupp C, Hunger A, Körbelin J, Pahrmann C, Schrepfer S, Müller OJ, Kleinschmidt JA, Trepel M.

PLoS One. 2011;6(8):e23101. doi: 10.1371/journal.pone.0023101. Epub 2011 Aug 5.


Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Lisowski L, Dane AP, Chu K, Zhang Y, Cunningham SC, Wilson EM, Nygaard S, Grompe M, Alexander IE, Kay MA.

Nature. 2014 Feb 20;506(7488):382-6. doi: 10.1038/nature12875. Epub 2013 Dec 25.


Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.

Kay CN, Ryals RC, Aslanidi GV, Min SH, Ruan Q, Sun J, Dyka FM, Kasuga D, Ayala AE, Van Vliet K, Agbandje-McKenna M, Hauswirth WW, Boye SL, Boye SE.

PLoS One. 2013 Apr 26;8(4):e62097. doi: 10.1371/journal.pone.0062097. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/99ee1789-a658-4fb0-8593-40a40e9f344a.


Enhancing transduction of the liver by adeno-associated viral vectors.

Nathwani AC, Cochrane M, McIntosh J, Ng CY, Zhou J, Gray JT, Davidoff AM.

Gene Ther. 2009 Jan;16(1):60-9. doi: 10.1038/gt.2008.137. Epub 2008 Aug 14.


Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway.

Davidoff AM, Ng CY, Zhou J, Spence Y, Nathwani AC.

Blood. 2003 Jul 15;102(2):480-8. Epub 2003 Mar 13.


Transduction of the central nervous system after intracerebroventricular injection of adeno-associated viral vectors in neonatal and juvenile mice.

Gholizadeh S, Tharmalingam S, Macaldaz ME, Hampson DR.

Hum Gene Ther Methods. 2013 Aug;24(4):205-13. doi: 10.1089/hgtb.2013.076. Epub 2013 Aug 3.


Characterization of the relationship of AAV capsid domain swapping to liver transduction efficiency.

Shen X, Storm T, Kay MA.

Mol Ther. 2007 Nov;15(11):1955-62. Epub 2007 Aug 28.


Targeted modifications in adeno-associated virus serotype 8 capsid improves its hepatic gene transfer efficiency in vivo.

Sen D, Gadkari RA, Sudha G, Gabriel N, Kumar YS, Selot R, Samuel R, Rajalingam S, Ramya V, Nair SC, Srinivasan N, Srivastava A, Jayandharan GR.

Hum Gene Ther Methods. 2013 Apr;24(2):104-16. doi: 10.1089/hgtb.2012.195.


Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration.

Bostick B, Ghosh A, Yue Y, Long C, Duan D.

Gene Ther. 2007 Nov;14(22):1605-9. Epub 2007 Sep 27.


Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential.

Li Q, Miller R, Han PY, Pang J, Dinculescu A, Chiodo V, Hauswirth WW.

Mol Vis. 2008 Sep 24;14:1760-9.


AAV-mediated liver-directed gene therapy.

Sands MS.

Methods Mol Biol. 2011;807:141-57. doi: 10.1007/978-1-61779-370-7_6.


Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells.

Nicklin SA, Buening H, Dishart KL, de Alwis M, Girod A, Hacker U, Thrasher AJ, Ali RR, Hallek M, Baker AH.

Mol Ther. 2001 Sep;4(3):174-81.


Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.

Ogura T, Mizukami H, Mimuro J, Madoiwa S, Okada T, Matsushita T, Urabe M, Kume A, Hamada H, Yoshikawa H, Sakata Y, Ozawa K.

J Gene Med. 2006 Aug;8(8):990-7.


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