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Items: 1 to 20 of 105


Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.

Elbediwy A, Zihni C, Terry SJ, Clark P, Matter K, Balda MS.

J Cell Biol. 2012 Aug 20;198(4):677-93. doi: 10.1083/jcb.201202094. Epub 2012 Aug 13.


The interdependence of the Rho GTPases and apicobasal cell polarity.

Mack NA, Georgiou M.

Small GTPases. 2014;5(2):10. doi: 10.4161/21541248.2014.973768. Review.


Epithelial junctions and Rho family GTPases: the zonular signalosome.

Citi S, Guerrera D, Spadaro D, Shah J.

Small GTPases. 2014;5(4):1-15. doi: 10.4161/21541248.2014.973760. Review.


Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation.

Zihni C, Munro PM, Elbediwy A, Keep NH, Terry SJ, Harris J, Balda MS, Matter K.

J Cell Biol. 2014 Jan 6;204(1):111-27. doi: 10.1083/jcb.201304064. Epub 2013 Dec 30.


Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

Hopkins AM, Walsh SV, Verkade P, Boquet P, Nusrat A.

J Cell Sci. 2003 Feb 15;116(Pt 4):725-42.


Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact.

Noritake J, Fukata M, Sato K, Nakagawa M, Watanabe T, Izumi N, Wang S, Fukata Y, Kaibuchi K.

Mol Biol Cell. 2004 Mar;15(3):1065-76. Epub 2003 Dec 29.


Newly formed E-cadherin contacts do not activate Cdc42 or induce filopodia protrusion in human keratinocytes.

Erasmus J, Aresta S, Nola S, Caron E, Braga VM.

Biol Cell. 2009 Sep 23;102(1):13-24. doi: 10.1042/BC20090048.


A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.

Wells CD, Fawcett JP, Traweger A, Yamanaka Y, Goudreault M, Elder K, Kulkarni S, Gish G, Virag C, Lim C, Colwill K, Starostine A, Metalnikov P, Pawson T.

Cell. 2006 May 5;125(3):535-48.


Rich1 negatively regulates the epithelial cell cycle, proliferation and adhesion by CDC42/RAC1-PAK1-Erk1/2 pathway.

Zhang J, Wang J, Zhou YF, Ren XY, Lin MM, Zhang QQ, Wang YH, Li X.

Cell Signal. 2015 Sep;27(9):1703-12. doi: 10.1016/j.cellsig.2015.05.009. Epub 2015 May 22.


Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells.

Otani T, Ichii T, Aono S, Takeichi M.

J Cell Biol. 2006 Oct 9;175(1):135-46. Epub 2006 Oct 2.


Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics.

Dubois T, Paléotti O, Mironov AA, Fraisier V, Stradal TE, De Matteis MA, Franco M, Chavrier P.

Nat Cell Biol. 2005 Apr;7(4):353-64. Epub 2005 Mar 27.


Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B.

Wallace SW, Durgan J, Jin D, Hall A.

Mol Biol Cell. 2010 Sep 1;21(17):2996-3006. doi: 10.1091/mbc.E10-05-0429. Epub 2010 Jul 14.


PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

Yamanaka T, Horikoshi Y, Suzuki A, Sugiyama Y, Kitamura K, Maniwa R, Nagai Y, Yamashita A, Hirose T, Ishikawa H, Ohno S.

Genes Cells. 2001 Aug;6(8):721-31.


The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells.

Zuo X, Fogelgren B, Lipschutz JH.

J Biol Chem. 2011 Jun 24;286(25):22469-77. doi: 10.1074/jbc.M111.238469. Epub 2011 May 4.


Desmoglein 3 acting as an upstream regulator of Rho GTPases, Rac-1/Cdc42 in the regulation of actin organisation and dynamics.

Tsang SM, Brown L, Gadmor H, Gammon L, Fortune F, Wheeler A, Wan H.

Exp Cell Res. 2012 Nov 1;318(18):2269-83. doi: 10.1016/j.yexcr.2012.07.002. Epub 2012 Jul 13.


Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis.

Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K.

Nat Cell Biol. 2011 Feb;13(2):159-66. doi: 10.1038/ncb2156. Epub 2011 Jan 23.


The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.

Rodriguez-Fraticelli AE, Vergarajauregui S, Eastburn DJ, Datta A, Alonso MA, Mostov K, Martín-Belmonte F.

J Cell Biol. 2010 May 17;189(4):725-38. doi: 10.1083/jcb.201002047.


Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts.

van Duijn TJ, Anthony EC, Hensbergen PJ, Deelder AM, Hordijk PL.

J Biol Chem. 2010 Jun 25;285(26):20137-46. doi: 10.1074/jbc.M109.099481. Epub 2010 Apr 19.

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