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Items: 1 to 20 of 121

1.

Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases.

Schwalm S, Pfeilschifter J, Huwiler A.

Biochim Biophys Acta. 2013 Jan;1831(1):239-50. doi: 10.1016/j.bbalip.2012.07.022. Epub 2012 Aug 4. Review.

PMID:
22889995
2.

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases.

Takuwa Y, Ikeda H, Okamoto Y, Takuwa N, Yoshioka K.

Biochim Biophys Acta. 2013 Jan;1831(1):185-92. doi: 10.1016/j.bbalip.2012.06.008. Epub 2012 Jun 23. Review.

PMID:
22735357
3.

Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis.

Pyne NJ, Dubois G, Pyne S.

Biochim Biophys Acta. 2013 Jan;1831(1):228-38. doi: 10.1016/j.bbalip.2012.07.003. Epub 2012 Jul 16. Review.

PMID:
22801038
4.

Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases.

Schwalm S, Pfeilschifter J, Huwiler A.

Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):44-9. doi: 10.1111/bcpt.12103. Epub 2013 Jul 15. Review.

5.

Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?

Vestri A, Pierucci F, Frati A, Monaco L, Meacci E.

Front Pharmacol. 2017 Jun 2;8:296. doi: 10.3389/fphar.2017.00296. eCollection 2017. Review.

6.

Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis.

Yang L, Yue S, Yang L, Liu X, Han Z, Zhang Y, Li L.

J Hepatol. 2013 Jul;59(1):114-23. doi: 10.1016/j.jhep.2013.02.021. Epub 2013 Mar 4.

PMID:
23466305
7.
8.

Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure.

Meissner A, Yang J, Kroetsch JT, Sauvé M, Dax H, Momen A, Noyan-Ashraf MH, Heximer S, Husain M, Lidington D, Bolz SS.

Circulation. 2012 Jun 5;125(22):2739-50. doi: 10.1161/CIRCULATIONAHA.111.047316. Epub 2012 Apr 25.

9.

Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator.

Takuwa Y, Okamoto H, Takuwa N, Gonda K, Sugimoto N, Sakurada S.

Mol Cell Endocrinol. 2001 May 25;177(1-2):3-11. Review.

PMID:
11377814
10.

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts.

Gellings Lowe N, Swaney JS, Moreno KM, Sabbadini RA.

Cardiovasc Res. 2009 May 1;82(2):303-12. doi: 10.1093/cvr/cvp056. Epub 2009 Feb 19.

11.

Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids.

Kihara A.

Biochim Biophys Acta. 2014 May;1841(5):766-72. doi: 10.1016/j.bbalip.2013.08.014. Epub 2013 Aug 27. Review.

PMID:
23994042
12.

Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.

Shea BS, Tager AM.

Proc Am Thorac Soc. 2012 Jul;9(3):102-10. doi: 10.1513/pats.201201-005AW. Review.

13.

Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye.

Swaney JS, Moreno KM, Gentile AM, Sabbadini RA, Stoller GL.

Exp Eye Res. 2008 Oct;87(4):367-75. doi: 10.1016/j.exer.2008.07.005. Epub 2008 Jul 18.

PMID:
18687328
14.

Molecular and physiological functions of sphingosine 1-phosphate transporters.

Nishi T, Kobayashi N, Hisano Y, Kawahara A, Yamaguchi A.

Biochim Biophys Acta. 2014 May;1841(5):759-65. doi: 10.1016/j.bbalip.2013.07.012. Epub 2013 Aug 4. Review.

PMID:
23921254
15.

Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets.

Melendez AJ.

Biochim Biophys Acta. 2008 Jan;1784(1):66-75. Epub 2007 Aug 14. Review.

PMID:
17913601
16.

Targeting sphingosine-1-phosphate in hematologic malignancies.

Stevenson CE, Takabe K, Nagahashi M, Milstien S, Spiegel S.

Anticancer Agents Med Chem. 2011 Nov;11(9):794-8. Review.

17.

The outs and the ins of sphingosine-1-phosphate in immunity.

Spiegel S, Milstien S.

Nat Rev Immunol. 2011 Jun;11(6):403-15. doi: 10.1038/nri2974. Epub 2011 May 6. Review.

18.

Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation.

Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, Stefansson S, Liau G, Hla T.

J Biol Chem. 2002 Feb 22;277(8):6667-75. Epub 2001 Dec 10.

19.

Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.

Natarajan V, Dudek SM, Jacobson JR, Moreno-Vinasco L, Huang LS, Abassi T, Mathew B, Zhao Y, Wang L, Bittman R, Weichselbaum R, Berdyshev E, Garcia JG.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):6-17. doi: 10.1165/rcmb.2012-0411TR. Review.

20.

Sphingosine 1-phosphate, a key mediator of the cytokine network: juxtacrine signaling.

Xia P, Wadham C.

Cytokine Growth Factor Rev. 2011 Feb;22(1):45-53. doi: 10.1016/j.cytogfr.2010.09.004. Epub 2010 Nov 3. Review.

PMID:
21051273

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