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Items: 1 to 20 of 152

1.

mTOR, metabolism, and the regulation of T-cell differentiation and function.

Waickman AT, Powell JD.

Immunol Rev. 2012 Sep;249(1):43-58. doi: 10.1111/j.1600-065X.2012.01152.x. Review.

2.

The role and regulation of mTOR in T-lymphocyte function.

O'Brien TF, Zhong XP.

Arch Immunol Ther Exp (Warsz). 2012 Jun;60(3):173-81. doi: 10.1007/s00005-012-0171-4. Epub 2012 Apr 8. Review.

3.

Regulation and function of mTOR signalling in T cell fate decisions.

Chi H.

Nat Rev Immunol. 2012 Apr 20;12(5):325-38. doi: 10.1038/nri3198. Review.

4.

Regulation of immune responses by mTOR.

Powell JD, Pollizzi KN, Heikamp EB, Horton MR.

Annu Rev Immunol. 2012;30:39-68. doi: 10.1146/annurev-immunol-020711-075024. Epub 2011 Nov 29. Review.

5.

Sensing the immune microenvironment to coordinate T cell metabolism, differentiation & function.

Heikamp EB, Powell JD.

Semin Immunol. 2012 Dec;24(6):414-20. doi: 10.1016/j.smim.2012.12.003. Epub 2013 Jan 14. Review.

6.

Regulation of T cells by mTOR: the known knowns and the known unknowns.

Pollizzi KN, Powell JD.

Trends Immunol. 2015 Jan;36(1):13-20. doi: 10.1016/j.it.2014.11.005. Epub 2014 Dec 16. Review.

7.

mTOR and metabolic pathways in T cell quiescence and functional activation.

Yang K, Chi H.

Semin Immunol. 2012 Dec;24(6):421-8. doi: 10.1016/j.smim.2012.12.004. Epub 2013 Feb 1. Review.

8.

mTOR signalling and metabolic regulation of T cell differentiation.

Peter C, Waldmann H, Cobbold SP.

Curr Opin Immunol. 2010 Oct;22(5):655-61. doi: 10.1016/j.coi.2010.08.010. Epub 2010 Sep 15. Review.

PMID:
20833524
9.

Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells.

Waickman AT, Powell JD.

J Immunol. 2012 May 15;188(10):4721-9. doi: 10.4049/jimmunol.1103143. Review.

10.

mTOR and lymphocyte metabolism.

Zeng H, Chi H.

Curr Opin Immunol. 2013 Jun;25(3):347-55. doi: 10.1016/j.coi.2013.05.002. Epub 2013 May 28. Review.

11.

Insight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection.

Lo YC, Lee CF, Powell JD.

Curr Opin Organ Transplant. 2014 Aug;19(4):363-71. doi: 10.1097/MOT.0000000000000098. Review.

12.

mTOR, linking metabolism and immunity.

Xu X, Ye L, Araki K, Ahmed R.

Semin Immunol. 2012 Dec;24(6):429-35. doi: 10.1016/j.smim.2012.12.005. Epub 2013 Jan 24. Review.

13.

mTOR signaling and metabolic regulation of T cells: new potential therapeutic targets in autoimmune diseases.

Pierdominici M, Vacirca D, Delunardo F, Ortona E.

Curr Pharm Des. 2011 Dec;17(35):3888-97. Review.

PMID:
21933144
14.

mTOR signaling in T cell immunity and autoimmunity.

Liu Y, Zhang DT, Liu XG.

Int Rev Immunol. 2015 Jan;34(1):50-66. doi: 10.3109/08830185.2014.933957. Epub 2014 Jul 14. Review.

PMID:
25019278
15.

Fine-tuning CD8(+) T cell functional responses: mTOR acts as a rheostat for regulating CD8(+) T cell proliferation, survival and differentiation?

Rao RR, Li Q, Shrikant PA.

Cell Cycle. 2010 Aug 1;9(15):2996-3001. doi: 10.4161/cc.9.15.12359. Epub 2010 Aug 12.

PMID:
20699660
16.

A modified model of T-cell differentiation based on mTOR activity and metabolism.

Powell JD, Heikamp EB, Pollizzi KN, Waickman AT.

Cold Spring Harb Symp Quant Biol. 2013;78:125-30. doi: 10.1101/sqb.2013.78.020214. Epub 2013 Oct 7.

17.

mTOR regulates T-cell differentiation and activation in immunity and autoimmunity.

Bi Y, Liu G, Yang R.

Crit Rev Eukaryot Gene Expr. 2011;21(4):313-22. Review.

PMID:
22181701
18.

The mTOR pathway and integrating immune regulation.

Cobbold SP.

Immunology. 2013 Dec;140(4):391-8. doi: 10.1111/imm.12162. Review.

19.

The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism.

Powell JD, Delgoffe GM.

Immunity. 2010 Sep 24;33(3):301-11. doi: 10.1016/j.immuni.2010.09.002. Review.

20.

Negative regulation of mTOR activation by diacylglycerol kinases.

Gorentla BK, Wan CK, Zhong XP.

Blood. 2011 Apr 14;117(15):4022-31. doi: 10.1182/blood-2010-08-300731. Epub 2011 Feb 10.

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