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CD44(+) cells have cancer stem cell-like properties in nasopharyngeal carcinoma.

Janisiewicz AM, Shin JH, Murillo-Sauca O, Kwok S, Le QT, Kong C, Kaplan MJ, Sunwoo JB.

Int Forum Allergy Rhinol. 2012 Nov;2(6):465-70. doi: 10.1002/alr.21068. Epub 2012 Aug 7.


CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.

Lun SW, Cheung ST, Cheung PF, To KF, Woo JK, Choy KW, Chow C, Cheung CC, Chung GT, Cheng AS, Ko CW, Tsao SW, Busson P, Ng MH, Lo KW.

PLoS One. 2012;7(12):e52426. doi: 10.1371/journal.pone.0052426. Epub 2012 Dec 21.


Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway.

Yang CF, Peng LX, Huang TJ, Yang GD, Chu QQ, Liang YY, Cao X, Xie P, Zheng LS, Huang HB, Cai MD, Huang JL, Liu RY, Zhu ZY, Qian CN, Huang BJ.

Cancer Lett. 2014 Mar 28;344(2):260-71. doi: 10.1016/j.canlet.2013.11.006. Epub 2013 Nov 19.


Cancer stem-like cells enriched with CD29 and CD44 markers exhibit molecular characteristics with epithelial-mesenchymal transition in squamous cell carcinoma.

Geng S, Guo Y, Wang Q, Li L, Wang J.

Arch Dermatol Res. 2013 Jan;305(1):35-47. doi: 10.1007/s00403-012-1260-2. Epub 2012 Jun 28. Erratum in: Arch Dermatol Res. 2017 Apr 7;:.


Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma.

Kong QL, Hu LJ, Cao JY, Huang YJ, Xu LH, Liang Y, Xiong D, Guan S, Guo BH, Mai HQ, Chen QY, Zhang X, Li MZ, Shao JY, Qian CN, Xia YF, Song LB, Zeng YX, Zeng MS.

PLoS Pathog. 2010 Jun 3;6(6):e1000940. doi: 10.1371/journal.ppat.1000940.


Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin.

Chan KC, Chan LS, Ip JC, Lo C, Yip TT, Ngan RK, Wong RN, Lo KW, Ng WT, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK.

Sci Rep. 2015 Apr 21;5:9979. doi: 10.1038/srep09979.


A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation.

Chan KC, Ting CM, Chan PS, Lo MC, Lo KW, Curry JE, Smyth T, Lee AW, Ng WT, Tsao GS, Wong RN, Lung ML, Mak NK.

Mol Cancer. 2013 Oct 24;12(1):128. doi: 10.1186/1476-4598-12-128.


Downregulation of Bmi-1 is associated with suppressed tumorigenesis and induced apoptosis in CD44⁺ nasopharyngeal carcinoma cancer stem-like cells.

Xu X, Liu Y, Su J, Li D, Hu J, Huang Q, Lu M, Liu X, Ren J, Chen W, Sun L.

Oncol Rep. 2016 Feb;35(2):923-31. doi: 10.3892/or.2015.4414. Epub 2015 Nov 12.


Identification of cancer stem-like CD44+ cells in human nasopharyngeal carcinoma cell line.

Su J, Xu XH, Huang Q, Lu MQ, Li DJ, Xue F, Yi F, Ren JH, Wu YP.

Arch Med Res. 2011 Jan;42(1):15-21. doi: 10.1016/j.arcmed.2011.01.007.


Identification of CD44+CD24+ gastric cancer stem cells.

Zhang C, Li C, He F, Cai Y, Yang H.

J Cancer Res Clin Oncol. 2011 Nov;137(11):1679-86. doi: 10.1007/s00432-011-1038-5. Epub 2011 Sep 1.


CD44 as a molecular marker to screen cancer stem cells in hypopharyngeal cancer.

Shen C, Xiang M, Nie C, Hu H, Ma Y, Wu H.

Acta Otolaryngol. 2013 Nov;133(11):1219-26. doi: 10.3109/00016489.2013.811750. Epub 2013 Jul 9.


Oropharyngeal malignant epithelial cell, lymphocyte and macrophage CD44 surface receptors for hyaluronate are expressed in sustained EBV infection: immunohistochemical data and EBV DNA tissue indices.

Groma V, Kazanceva A, Nora-Krukle Z, Murovska M.

Pathol Res Pract. 2012 Sep 15;208(9):518-26. doi: 10.1016/j.prp.2012.05.017. Epub 2012 Jul 6.


Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties.

Wang M, Xiao J, Shen M, Yahong Y, Tian R, Zhu F, Jiang J, Du Z, Hu J, Liu W, Qin R.

Int J Cancer. 2011 Jan 1;128(1):72-81. doi: 10.1002/ijc.25317.


Identification of gastric cancer stem cells using the cell surface marker CD44.

Takaishi S, Okumura T, Tu S, Wang SS, Shibata W, Vigneshwaran R, Gordon SA, Shimada Y, Wang TC.

Stem Cells. 2009 May;27(5):1006-20. doi: 10.1002/stem.30.


Cancer stem cells from colorectal cancer-derived cell lines.

Yeung TM, Gandhi SC, Wilding JL, Muschel R, Bodmer WF.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3722-7. doi: 10.1073/pnas.0915135107. Epub 2010 Feb 2.


CD44 is associated with the aggressive phenotype of nasopharyngeal carcinoma through redox regulation.

Lin CH, Hung PH, Chen YJ.

Int J Mol Sci. 2013 Jun 26;14(7):13266-81. doi: 10.3390/ijms140713266.


Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line.

Wang J, Guo LP, Chen LZ, Zeng YX, Lu SH.

Cancer Res. 2007 Apr 15;67(8):3716-24.


Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus.

Cheung ST, Huang DP, Hui AB, Lo KW, Ko CW, Tsang YS, Wong N, Whitney BM, Lee JC.

Int J Cancer. 1999 Sep 24;83(1):121-6.


Induction of metastatic cancer stem cells from the NK/LAK-resistant floating, but not adherent, subset of the UP-LN1 carcinoma cell line by IFN-γ.

Chen HC, Chou AS, Liu YC, Hsieh CH, Kang CC, Pang ST, Yeh CT, Liu HP, Liao SK.

Lab Invest. 2011 Oct;91(10):1502-13. doi: 10.1038/labinvest.2011.91. Epub 2011 Jun 20.

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