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Items: 1 to 20 of 85

1.

Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene.

Hovhannisyan H, Zhang Y, Hassan MQ, Wu H, Glackin C, Lian JB, Stein JL, Montecino M, Stein GS, van Wijnen AJ.

J Cell Physiol. 2013 Feb;228(2):313-21. doi: 10.1002/jcp.22109.

2.

SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.

Cruzat F, Henriquez B, Villagra A, Hepp M, Lian JB, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS, Montecino M.

Biochemistry. 2009 Aug 4;48(30):7287-95. doi: 10.1021/bi9004792.

3.

Dlx5 and mef2 regulate a novel runx2 enhancer for osteoblast-specific expression.

Kawane T, Komori H, Liu W, Moriishi T, Miyazaki T, Mori M, Matsuo Y, Takada Y, Izumi S, Jiang Q, Nishimura R, Kawai Y, Komori T.

J Bone Miner Res. 2014 Sep;29(9):1960-9. doi: 10.1002/jbmr.2240.

4.

Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats).

Zhang Y, Hassan MQ, Xie RL, Hawse JR, Spelsberg TC, Montecino M, Stein JL, Lian JB, van Wijnen AJ, Stein GS.

J Biol Chem. 2009 Jan 30;284(5):3125-35. doi: 10.1074/jbc.M807466200. Epub 2008 Nov 18.

5.

Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.

Xiao Z, Zhang S, Magenheimer BS, Luo J, Quarles LD.

J Biol Chem. 2008 May 2;283(18):12624-34. doi: 10.1074/jbc.M710407200. Epub 2008 Mar 5.

6.

Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region.

Tai PW, Wu H, Gordon JA, Whitfield TW, Barutcu AR, van Wijnen AJ, Lian JB, Stein GS, Stein JL.

Gene. 2014 Oct 15;550(1):1-9. doi: 10.1016/j.gene.2014.05.044. Epub 2014 Jun 2.

7.

Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.

Drissi H, Pouliot A, Stein JL, van Wijnen AJ, Stein GS, Lian JB.

J Cell Biochem. 2002;86(2):403-12.

PMID:
12112009
9.

General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2.

Yu S, Jiang Y, Galson DL, Luo M, Lai Y, Lu Y, Ouyang HJ, Zhang J, Xiao G.

J Biol Chem. 2008 Feb 29;283(9):5542-53. doi: 10.1074/jbc.M705653200. Epub 2008 Jan 2.

10.
11.

Comparative analysis of osteoblast gene expression profiles and Runx2 genomic occupancy of mouse and human osteoblasts in vitro.

Tarkkonen K, Hieta R, Kytölä V, Nykter M, Kiviranta R.

Gene. 2017 Aug 30;626:119-131. doi: 10.1016/j.gene.2017.05.028. Epub 2017 May 11.

12.

The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter.

Barutcu AR, Tai PW, Wu H, Gordon JA, Whitfield TW, Dobson JR, Imbalzano AN, Lian JB, van Wijnen AJ, Stein JL, Stein GS.

Nucleic Acids Res. 2014;42(16):10360-72. doi: 10.1093/nar/gku712. Epub 2014 Aug 12.

13.

Runx2 recruits p300 to mediate parathyroid hormone's effects on histone acetylation and transcriptional activation of the matrix metalloproteinase-13 gene.

Boumah CE, Lee M, Selvamurugan N, Shimizu E, Partridge NC.

Mol Endocrinol. 2009 Aug;23(8):1255-63. doi: 10.1210/me.2008-0217. Epub 2009 May 7.

14.
15.

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.

Wu H, Whitfield TW, Gordon JA, Dobson JR, Tai PW, van Wijnen AJ, Stein JL, Stein GS, Lian JB.

Genome Biol. 2014 Mar 21;15(3):R52. doi: 10.1186/gb-2014-15-3-r52.

16.

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells.

Paredes R, Arriagada G, Cruzat F, Villagra A, Olate J, Zaidi K, van Wijnen A, Lian JB, Stein GS, Stein JL, Montecino M.

Mol Cell Biol. 2004 Oct;24(20):8847-61.

17.

Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways.

Rodríguez-Carballo E, Ulsamer A, Susperregui AR, Manzanares-Céspedes C, Sánchez-García E, Bartrons R, Rosa JL, Ventura F.

J Bone Miner Res. 2011 Apr;26(4):718-29. doi: 10.1002/jbmr.260.

18.

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation.

Liu JC, Lengner CJ, Gaur T, Lou Y, Hussain S, Jones MD, Borodic B, Colby JL, Steinman HA, van Wijnen AJ, Stein JL, Jones SN, Stein GS, Lian JB.

J Biol Chem. 2011 Aug 26;286(34):30057-70. doi: 10.1074/jbc.M111.241505. Epub 2011 Jun 15.

19.

Human estrogen receptor alpha gene is a target of Runx2 transcription factor in osteoblasts.

Lambertini E, Penolazzi L, Tavanti E, Schincaglia GP, Zennaro M, Gambari R, Piva R.

Exp Cell Res. 2007 May 1;313(8):1548-60. Epub 2007 Feb 7.

PMID:
17350616
20.

Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator.

Tamiya H, Ikeda T, Jeong JH, Saito T, Yano F, Jung YK, Ohba S, Kawaguchi H, Chung UI, Choi JY.

Gene. 2008 Jun 15;416(1-2):53-60. doi: 10.1016/j.gene.2008.03.003. Epub 2008 Mar 15.

PMID:
18442887

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