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Items: 1 to 20 of 120

1.

Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice.

Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI 2nd, Harris RA.

Anesthesiology. 2012 Oct;117(4):765-71.

2.

Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.

Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA.

J Pharmacol Exp Ther. 2012 Feb;340(2):304-16. doi: 10.1124/jpet.111.185116. Epub 2011 Oct 28.

3.

Glycine receptors mediate part of the immobility produced by inhaled anesthetics.

Zhang Y, Laster MJ, Hara K, Harris RA, Eger EI 2nd, Stabernack CR, Sonner JM.

Anesth Analg. 2003 Jan;96(1):97-101, table of contents.

PMID:
12505932
5.

Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol.

Naito A, Muchhala KH, Trang J, Asatryan L, Trudell JR, Homanics GE, Alkana RL, Davies DL.

Neuroscience. 2015 Jun 25;297:68-77. doi: 10.1016/j.neuroscience.2015.03.034. Epub 2015 Mar 28.

6.

The anesthetic-like effects of diverse compounds on wild-type and mutant gamma-aminobutyric acid type A and glycine receptors.

Yang L, Sonner JM.

Anesth Analg. 2008 Mar;106(3):838-45, table of contents. doi: 10.1213/ane.0b013e31816095bd.

PMID:
18292428
7.

Divergence of volatile anesthetic effects in inhibitory neurotransmitter receptors.

Greenblatt EP, Meng X.

Anesthesiology. 2001 Jun;94(6):1026-33.

PMID:
11465594
8.

Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.

Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI 2nd.

Anesth Analg. 2005 Aug;101(2):412-8, table of contents.

PMID:
16037154
9.
11.

Subunit-dependent block by isoflurane of wild-type and mutant alpha(1)S270H GABA(A) receptor currents in Xenopus oocytes.

Hall AC, Stevens RJ, Betts BA, Yeung WY, Kelley JC, Harrison NL.

Neurosci Lett. 2005 Jul 15;382(3):332-7. Epub 2005 Apr 14.

PMID:
15925114
12.

Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.

Blednov YA, Benavidez JM, Homanics GE, Harris RA.

J Pharmacol Exp Ther. 2012 Feb;340(2):317-29. doi: 10.1124/jpet.111.185124. Epub 2011 Oct 28.

13.

Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.

O'Shea SM, Becker L, Weiher H, Betz H, Laube B.

J Neurosci. 2004 Mar 3;24(9):2322-7.

15.

Anesthetic and ethanol effects on spontaneously opening glycine receptor channels.

Beckstead MJ, Phelan R, Trudell JR, Bianchini MJ, Mihic SJ.

J Neurochem. 2002 Sep;82(6):1343-51.

16.
17.

Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane.

Zhang Y, Sonner JM, Eger EI 2nd, Stabernack CR, Laster MJ, Raines DE, Harris RA.

Anesth Analg. 2004 Jul;99(1):85-90.

PMID:
15281509
18.
19.
20.

The effect of three inhaled anesthetics in mice harboring mutations in the GluR6 (kainate) receptor gene.

Sonner JM, Vissel B, Royle G, Maurer A, Gong D, Baron NV, Harrison N, Fanselow M, Eger EI 2nd.

Anesth Analg. 2005 Jul;101(1):143-8, table of contents.

PMID:
15976221

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