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Items: 1 to 20 of 93

1.

c-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5.

Ren X, Xu J, Cooper JP, Kang MH, Erdreich-Epstein A.

PLoS One. 2012;7(8):e42291. doi: 10.1371/journal.pone.0042291. Epub 2012 Aug 3.

2.

Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways.

Erdreich-Epstein A, Tran LB, Cox OT, Huang EY, Laug WE, Shimada H, Millard M.

Blood. 2005 Jun 1;105(11):4353-61. Epub 2005 Feb 10.

3.

c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.

Xu J, Millard M, Ren X, Cox OT, Erdreich-Epstein A.

Blood. 2010 Apr 1;115(13):2709-18. doi: 10.1182/blood-2009-05-223776. Epub 2010 Feb 2.

5.

Induction of apoptosis of integrin-expressing human prostate cancer cells by cyclic Arg-Gly-Asp peptides.

Chatterjee S, Brite KH, Matsumura A.

Clin Cancer Res. 2001 Oct;7(10):3006-11.

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The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.

Le XF, Mao W, He G, Claret FX, Xia W, Ahmed AA, Hung MC, Siddik ZH, Bast RC Jr.

J Natl Cancer Inst. 2011 Sep 21;103(18):1403-22. doi: 10.1093/jnci/djr280. Epub 2011 Aug 2.

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11.

Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed αvβ3 and αvβ5 integrins.

Welser-Alves JV, Boroujerdi A, Tigges U, Milner R.

J Neuroinflammation. 2011 Nov 10;8:157. doi: 10.1186/1742-2094-8-157.

12.

Cell surface overexpression of alphavbeta5 integrin impedes alphavbeta3-mediated migration of the human ovarian adenocarcinoma cell line IGROV1.

Maubant S, Leroy-Dudal J, Carreiras F, Deslandes E, Duigou F, Staedel C, Gauduchon P.

Cell Biol Int. 2007 Feb;31(2):109-18. Epub 2006 Sep 23.

PMID:
17074516
13.

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone.

Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, Kallio M, Kähäri VM, Hietanen S.

PLoS One. 2014 Aug 22;9(8):e105526. doi: 10.1371/journal.pone.0105526. eCollection 2014.

15.

Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis.

Kondo T, Matsuda T, Kitano T, Takahashi A, Tashima M, Ishikura H, Umehara H, Domae N, Uchiyama T, Okazaki T.

J Biol Chem. 2000 Mar 17;275(11):7668-76.

16.

Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide.

Erdreich-Epstein A, Shimada H, Groshen S, Liu M, Metelitsa LS, Kim KS, Stins MF, Seeger RC, Durden DL.

Cancer Res. 2000 Feb 1;60(3):712-21.

17.

Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.

Chudakova DA, Zeidan YH, Wheeler BW, Yu J, Novgorodov SA, Kindy MS, Hannun YA, Gudz TI.

J Biol Chem. 2008 Oct 24;283(43):28806-16. doi: 10.1074/jbc.M803301200. Epub 2008 Aug 5.

18.

c-Abl mediates angiotensin II-induced apoptosis in podocytes.

Chen X, Ren Z, Liang W, Zha D, Liu Y, Chen C, Singhal PC, Ding G.

J Mol Histol. 2013 Oct;44(5):597-608. doi: 10.1007/s10735-013-9505-8. Epub 2013 Mar 21.

19.

Regulation of alphaVbeta3 and alphaVbeta5 integrins by dexamethasone in normal human osteoblastic cells.

Cheng SL, Lai CF, Fausto A, Chellaiah M, Feng X, McHugh KP, Teitelbaum SL, Civitelli R, Hruska KA, Ross FP, Avioli LV.

J Cell Biochem. 2000 Mar;77(2):265-76.

PMID:
10723092
20.

Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis.

Hood JD, Frausto R, Kiosses WB, Schwartz MA, Cheresh DA.

J Cell Biol. 2003 Sep 1;162(5):933-43.

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