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Items: 1 to 20 of 91

1.

Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation.

Handlogten MW, Kiziltepe T, Alves NJ, Bilgicer B.

ACS Chem Biol. 2012 Nov 16;7(11):1796-801. doi: 10.1021/cb300193f. Epub 2012 Aug 21.

2.
3.

Two-allergen model reveals complex relationship between IgE crosslinking and degranulation.

Handlogten MW, Deak PE, Bilgicer B.

Chem Biol. 2014 Nov 20;21(11):1445-51. doi: 10.1016/j.chembiol.2014.08.019. Epub 2014 Oct 9.

4.

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation.

Deak PE, Vrabel MR, Pizzuti VJ, Kiziltepe T, Bilgicer B.

Exp Biol Med (Maywood). 2016 May;241(9):996-1006. doi: 10.1177/1535370216644533. Epub 2016 Apr 13.

5.

Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation.

Handlogten MW, Kiziltepe T, Serezani AP, Kaplan MH, Bilgicer B.

Nat Chem Biol. 2013 Dec;9(12):789-95. doi: 10.1038/nchembio.1358. Epub 2013 Oct 6.

6.

Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge.

Christensen LH, Holm J, Lund G, Riise E, Lund K.

J Allergy Clin Immunol. 2008 Aug;122(2):298-304. doi: 10.1016/j.jaci.2008.05.026. Epub 2008 Jun 24.

PMID:
18572230
7.

Design of a heterobivalent ligand to inhibit IgE clustering on mast cells.

Handlogten MW, Kiziltepe T, Moustakas DT, Bilgiçer B.

Chem Biol. 2011 Sep 23;18(9):1179-88. doi: 10.1016/j.chembiol.2011.06.012.

8.
9.

A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo.

Handlogten MW, Serezani AP, Sinn AL, Pollok KE, Kaplan MH, Bilgicer B.

J Immunol. 2014 Mar 1;192(5):2035-41. doi: 10.4049/jimmunol.1301371. Epub 2014 Jan 31.

10.

Human serum IgE-mediated mast cell degranulation shows poor correlation to allergen-specific IgE content.

Marchand F, Mecheri S, Guilloux L, Iannascoli B, Weyer A, Blank U.

Allergy. 2003 Oct;58(10):1037-43.

11.

IgG-mediated down-regulation of IgE bound to mast cells: a potential novel mechanism of allergen-specific desensitization.

Uermösi C, Zabel F, Manolova V, Bauer M, Beerli RR, Senti G, Kündig TM, Saudan P, Bachmann MF.

Allergy. 2014 Mar;69(3):338-47. doi: 10.1111/all.12327. Epub 2013 Dec 19. Erratum in: Allergy. 2014 Aug;69(8):1118.

12.

Antigen valency as a determinant of the responsiveness of IgE-sensitised rat basophil leukemia cells.

Collins AM, Thelian D, Basil M.

Int Arch Allergy Immunol. 1995 Aug;107(4):547-56.

PMID:
7620369
13.

FcepsilonRI-alpha siRNA inhibits the antigen-induced activation of mast cells.

Safaralizadeh R, Soheili ZS, Deezagi A, Pourpak Z, Samiei S, Moin M.

Iran J Allergy Asthma Immunol. 2009 Dec;8(4):177-83. doi: 08.04/ijaai.177183.

16.

Molecular determinants of allergen-induced effector cell degranulation.

Gieras A, Focke-Tejkl M, Ball T, Verdino P, Hartl A, Thalhamer J, Valenta R.

J Allergy Clin Immunol. 2007 Feb;119(2):384-90. Epub 2006 Nov 7.

PMID:
17291855
17.
18.

Mapping IgE-binding epitopes of Ric c 1 and Ric c 3, allergens from Ricinus communis, by mast cell degranulation assay.

Felix SP, Mayerhoffer RO, Damatta RA, Verícimo MA, Nascimento VV, Machado OL.

Peptides. 2008 Apr;29(4):497-504. doi: 10.1016/j.peptides.2007.12.013. Epub 2008 Jan 6.

PMID:
18262682
19.
20.

Evaluation of an in vitro method for the measurement of specific IgE antibody responses: the rat basophilic leukemia (RBL) cell assay.

Dearman RJ, Skinner RA, Deakin N, Shaw D, Kimber I.

Toxicology. 2005 Jan 15;206(2):195-205.

PMID:
15588913

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