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Functional magnetic resonance imaging analysis of food-related brain activity in patients with lipodystrophy undergoing leptin replacement therapy.

Aotani D, Ebihara K, Sawamoto N, Kusakabe T, Aizawa-Abe M, Kataoka S, Sakai T, Iogawa H, Ebihara C, Fujikura J, Hosoda K, Fukuyama H, Nakao K.

J Clin Endocrinol Metab. 2012 Oct;97(10):3663-71. doi: 10.1210/jc.2012-1872. Epub 2012 Aug 7.


Leptin regulates striatal regions and human eating behavior.

Farooqi IS, Bullmore E, Keogh J, Gillard J, O'Rahilly S, Fletcher PC.

Science. 2007 Sep 7;317(5843):1355. Epub 2007 Aug 9.


Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa.

Lawson EA, Holsen LM, Santin M, Meenaghan E, Eddy KT, Becker AE, Herzog DB, Goldstein JM, Klibanski A.

J Clin Endocrinol Metab. 2012 Oct;97(10):E1898-908. doi: 10.1210/jc.2012-1702. Epub 2012 Aug 7.


Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin-sensitive subjects without altering brain structure.

Farr OM, Fiorenza C, Papageorgiou P, Brinkoetter M, Ziemke F, Koo BB, Rojas R, Mantzoros CS.

J Clin Endocrinol Metab. 2014 Dec;99(12):E2529-38. doi: 10.1210/jc.2014-2774.


Neural responsivity to food cues in fasted and fed states pre and post gastric bypass surgery.

Ochner CN, Laferrère B, Afifi L, Atalayer D, Geliebter A, Teixeira J.

Neurosci Res. 2012 Oct;74(2):138-43. doi: 10.1016/j.neures.2012.08.002. Epub 2012 Aug 16.


Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy.

Williamson DA, Ravussin E, Wong ML, Wagner A, Dipaoli A, Caglayan S, Ozata M, Martin C, Walden H, Arnett C, Licinio J.

Appetite. 2005 Aug;45(1):75-80.


Importance of reward and prefrontal circuitry in hunger and satiety: Prader-Willi syndrome vs simple obesity.

Holsen LM, Savage CR, Martin LE, Bruce AS, Lepping RJ, Ko E, Brooks WM, Butler MG, Zarcone JR, Goldstein JM.

Int J Obes (Lond). 2012 May;36(5):638-47. doi: 10.1038/ijo.2011.204. Epub 2011 Oct 25.


Leptin replacement alters brain response to food cues in genetically leptin-deficient adults.

Baicy K, London ED, Monterosso J, Wong ML, Delibasi T, Sharma A, Licinio J.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18276-9. Epub 2007 Nov 6.


Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency.

McDuffie JR, Riggs PA, Calis KA, Freedman RJ, Oral EA, DePaoli AM, Yanovski JA.

J Clin Endocrinol Metab. 2004 Sep;89(9):4258-63.


Cerebral processing of food-related stimuli: effects of fasting and gender.

Uher R, Treasure J, Heining M, Brammer MJ, Campbell IC.

Behav Brain Res. 2006 Apr 25;169(1):111-9. Epub 2006 Jan 30.


GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans.

van Bloemendaal L, IJzerman RG, Ten Kulve JS, Barkhof F, Konrad RJ, Drent ML, Veltman DJ, Diamant M.

Diabetes. 2014 Dec;63(12):4186-96. doi: 10.2337/db14-0849. Epub 2014 Jul 28.


Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat.

Zorrilla EP, Inoue K, Valdez GR, Tabarin A, Koob GF.

Psychopharmacology (Berl). 2005 Jan;177(3):324-35. Epub 2004 Jul 27.


Separate systems for serotonin and leptin in appetite control.

Halford JC, Blundell JE.

Ann Med. 2000 Apr;32(3):222-32. Review.


Effects of leptin deficiency and replacement on cerebellar response to food-related cues.

Berman SM, Paz-Filho G, Wong ML, Kohno M, Licinio J, London ED.

Cerebellum. 2013 Feb;12(1):59-67. doi: 10.1007/s12311-012-0360-z.


Leptin therapy in a congenital leptin-deficient patient leads to acute and long-term changes in homeostatic, reward, and food-related brain areas.

Frank S, Heni M, Moss A, von Schnurbein J, Fritsche A, Häring HU, Farooqi S, Preissl H, Wabitsch M.

J Clin Endocrinol Metab. 2011 Aug;96(8):E1283-7. doi: 10.1210/jc.2010-2713. Epub 2011 May 18.


Genetic identification of a neural circuit that suppresses appetite.

Carter ME, Soden ME, Zweifel LS, Palmiter RD.

Nature. 2013 Nov 7;503(7474):111-4. doi: 10.1038/nature12596. Epub 2013 Oct 13.


Eating rate during a fixed-portion meal does not affect postprandial appetite and gut peptides or energy intake during a subsequent meal.

Karl JP, Young AJ, Montain SJ.

Physiol Behav. 2011 Mar 28;102(5):524-31. doi: 10.1016/j.physbeh.2011.01.007. Epub 2011 Jan 14.


Neural mechanisms underlying hyperphagia in Prader-Willi syndrome.

Holsen LM, Zarcone JR, Brooks WM, Butler MG, Thompson TI, Ahluwalia JS, Nollen NL, Savage CR.

Obesity (Silver Spring). 2006 Jun;14(6):1028-37.


Afferent signals regulating food intake.

Bray GA.

Proc Nutr Soc. 2000 Aug;59(3):373-84. Review.


Nicotine enhances modulation of food-cue reactivity by leptin and ghrelin in the ventromedial prefrontal cortex.

Kroemer NB, Wuttig F, Bidlingmaier M, Zimmermann US, Smolka MN.

Addict Biol. 2015 Jul;20(4):832-44. doi: 10.1111/adb.12167. Epub 2014 Jul 25.

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