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Items: 1 to 20 of 104

1.

Effects of sildenafil and/or muscle derived stem cells on myocardial infarction.

Wang JS, Kovanecz I, Vernet D, Nolazco G, Kopchok GE, Chow SL, White RA, Gonzalez-Cadavid NF.

J Transl Med. 2012 Aug 7;10:159. doi: 10.1186/1479-5876-10-159.

2.

Separate or combined treatments with daily sildenafil, molsidomine, or muscle-derived stem cells prevent erectile dysfunction in a rat model of cavernosal nerve damage.

Kovanecz I, Rivera S, Nolazco G, Vernet D, Segura D, Gharib S, Rajfer J, Gonzalez-Cadavid NF.

J Sex Med. 2012 Nov;9(11):2814-26. doi: 10.1111/j.1743-6109.2012.02913.x. Epub 2012 Sep 13.

3.

L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's fibrotic plaque and related fibroblast cultures.

Valente EG, Vernet D, Ferrini MG, Qian A, Rajfer J, Gonzalez-Cadavid NF.

Nitric Oxide. 2003 Dec;9(4):229-44.

PMID:
14996430
4.

Phosphodiesterase 5A inhibition induces Na+/H+ exchanger blockade and protection against myocardial infarction.

Pérez NG, Piaggio MR, Ennis IL, Garciarena CD, Morales C, Escudero EM, Cingolani OH, Chiappe de Cingolani G, Yang XP, Cingolani HE.

Hypertension. 2007 May;49(5):1095-103. Epub 2007 Mar 5.

5.

Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells following myocardial infarction in mice.

Hoke NN, Salloum FN, Kass DA, Das A, Kukreja RC.

Stem Cells. 2012 Feb;30(2):326-35. doi: 10.1002/stem.789.

6.

Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice.

Salloum FN, Abbate A, Das A, Houser JE, Mudrick CA, Qureshi IZ, Hoke NN, Roy SK, Brown WR, Prabhakar S, Kukreja RC.

Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1398-406. doi: 10.1152/ajpheart.91438.2007. Epub 2008 Jan 25.

7.

Effects of phosphodiesterase-5 inhibition by sildenafil in the pressure overloaded right heart.

Andersen A, Nielsen JM, Peters CD, Schou UK, Sloth E, Nielsen-Kudsk JE.

Eur J Heart Fail. 2008 Dec;10(12):1158-65. doi: 10.1016/j.ejheart.2008.09.016. Epub 2008 Nov 12.

8.

Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis in the rat.

Ferrini MG, Kovanecz I, Sanchez S, Vernet D, Davila HH, Rajfer J, Gonzalez-Cadavid NF.

Biol Reprod. 2007 May;76(5):915-23. Epub 2007 Feb 7.

PMID:
17287493
9.

Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway.

Chau VQ, Salloum FN, Hoke NN, Abbate A, Kukreja RC.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2272-9. doi: 10.1152/ajpheart.00654.2010. Epub 2011 Mar 11.

10.

Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat.

Rossoni G, Manfredi B, De Gennaro Colonna V, Berti M, Guazzi M, Berti F.

Br J Pharmacol. 2007 Mar;150(5):567-76. Epub 2007 Jan 22.

11.

Endothelial antioxidant administration ameliorates the erectile response to PDE5 regardless of the extension of the atherosclerotic process.

Vicari E, La Vignera S, Condorelli R, Calogero AE.

J Sex Med. 2010 Mar;7(3):1247-53. doi: 10.1111/j.1743-6109.2009.01420.x. Epub 2009 Aug 11.

PMID:
19674252
12.

Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

Xie YP, Chen B, Sanders P, Guo A, Li Y, Zimmerman K, Wang LC, Weiss RM, Grumbach IM, Anderson ME, Song LS.

Hypertension. 2012 Feb;59(2):355-62. doi: 10.1161/HYPERTENSIONAHA.111.180968. Epub 2011 Dec 27.

13.

Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1.

Koneru S, Varma Penumathsa S, Thirunavukkarasu M, Vidavalur R, Zhan L, Singal PK, Engelman RM, Das DK, Maulik N.

J Cell Mol Med. 2008 Dec;12(6B):2651-64. doi: 10.1111/j.1582-4934.2008.00319.x. Epub 2008 Mar 28.

14.

Selective PDE5A inhibition with sildenafil rescues left ventricular dysfunction, inflammatory immune response and cardiac remodeling in angiotensin II-induced heart failure in vivo.

Westermann D, Becher PM, Lindner D, Savvatis K, Xia Y, Fröhlich M, Hoffmann S, Schultheiss HP, Tschöpe C.

Basic Res Cardiol. 2012 Nov;107(6):308. doi: 10.1007/s00395-012-0308-y. Epub 2012 Nov 2. Erratum in: Basic Res Cardiol. 2013 Mar;108(2):327.

PMID:
23117837
15.

Long-term effects of sildenafil in a rat model of chronic mitral regurgitation: benefits of ventricular remodeling and exercise capacity.

Kim KH, Kim YJ, Ohn JH, Yang J, Lee SE, Lee SW, Kim HK, Seo JW, Sohn DW.

Circulation. 2012 Mar 20;125(11):1390-401. doi: 10.1161/CIRCULATIONAHA.111.065300. Epub 2012 Feb 8.

16.

Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats.

Kuang T, Wang J, Pang B, Huang X, Burg ED, Yuan JX, Wang C.

Pulm Pharmacol Ther. 2010 Oct;23(5):456-64. doi: 10.1016/j.pupt.2010.02.003. Epub 2010 Feb 23.

18.

Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.

Luong C, Rey-Perra J, Vadivel A, Gilmour G, Sauve Y, Koonen D, Walker D, Todd KG, Gressens P, Kassiri Z, Nadeem K, Morgan B, Eaton F, Dyck JR, Archer SL, Thébaud B.

Circulation. 2011 May 17;123(19):2120-31. doi: 10.1161/CIRCULATIONAHA.108.845909. Epub 2011 May 2.

19.

Phosphodiesterase type 5 inhibitors in pulmonary arterial hypertension.

Montani D, Chaumais MC, Savale L, Natali D, Price LC, Jaïs X, Humbert M, Simonneau G, Sitbon O.

Adv Ther. 2009 Sep;26(9):813-25. doi: 10.1007/s12325-009-0064-z. Epub 2009 Sep 19. Review.

PMID:
19768639
20.

Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects.

Toque HA, Priviero FB, Zemse SM, Antunes E, Teixeira CE, Webb RC.

Clin Exp Pharmacol Physiol. 2009 Apr;36(4):358-66. doi: 10.1111/j.1440-1681.2008.05071.x. Epub 2008 Oct 15.

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