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Items: 1 to 20 of 106

1.

Short hairpin RNA suppression of thymidylate synthase produces DNA mismatches and results in excellent radiosensitization.

Flanagan SA, Cooper KS, Mannava S, Nikiforov MA, Shewach DS.

Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):e613-20. doi: 10.1016/j.ijrobp.2012.06.050. Epub 2012 Aug 3.

2.

MLH1 deficiency enhances radiosensitization with 5-fluorodeoxyuridine by increasing DNA mismatches.

Flanagan SA, Krokosky CM, Mannava S, Nikiforov MA, Shewach DS.

Mol Pharmacol. 2008 Sep;74(3):863-71. doi: 10.1124/mol.107.043349. Epub 2008 Jun 5.

3.

The role of cell cycle redistribution in radiosensitization: implications regarding the mechanism of fluorodeoxyuridine radiosensitization.

McGinn CJ, Miller EM, Lindstrom MJ, Kunugi KA, Johnston PG, Kinsella TJ.

Int J Radiat Oncol Biol Phys. 1994 Nov 15;30(4):851-9.

PMID:
7960987
4.
5.

Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.

Grem JL, Danenberg KD, Kao V, Danenberg PV, Nguyen D.

Anticancer Drugs. 2002 Mar;13(3):259-70.

PMID:
11984070
7.

Fluorodeoxyuridine-mediated cytotoxicity and radiosensitization require S phase progression.

Lawrence TS, Davis MA, Tang HY, Maybaum J.

Int J Radiat Biol. 1996 Sep;70(3):273-80.

PMID:
8800198
8.
9.

Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.

Grem JL, Danenberg KD, Behan K, Parr A, Young L, Danenberg PV, Nguyen D, Drake J, Monks A, Allegra CJ.

Clin Cancer Res. 2001 Apr;7(4):999-1009.

10.

Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.

Huehls AM, Wagner JM, Huntoon CJ, Geng L, Erlichman C, Patel AG, Kaufmann SH, Karnitz LM.

Cancer Res. 2011 Jul 15;71(14):4944-54. doi: 10.1158/0008-5472.CAN-11-0814. Epub 2011 May 25.

11.

Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells.

Bruso CE, Shewach DS, Lawrence TS.

Int J Radiat Oncol Biol Phys. 1990 Dec;19(6):1411-7.

PMID:
2148170
12.
13.

Fluorodeoxyuridine-mediated modulation of iododeoxyuridine incorporation and radiosensitization in human colon cancer cells in vitro and in vivo.

Lawrence TS, Davis MA, McKeever PE, Maybaum J, Stetson PL, Normolle DP, Ensminger WD.

Cancer Res. 1991 Aug 1;51(15):3900-5.

14.

Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.

Zhang ZG, Malmberg M, Yin MB, Slocum HK, Rustum YM.

Biochem Pharmacol. 1993 Mar 9;45(5):1157-64.

PMID:
8461045
16.

Different mechanisms of acquired resistance to fluorinated pyrimidines in human colorectal cancer cells.

Murakami Y, Kazuno H, Emura T, Tsujimoto H, Suzuki N, Fukushima M.

Int J Oncol. 2000 Aug;17(2):277-83.

PMID:
10891536
18.

The effect of activation of wild-type p53 function on fluoropyrimidine-mediated radiosensitization.

Naida JD, Davis MA, Lawrence TS.

Int J Radiat Oncol Biol Phys. 1998 Jun 1;41(3):675-80.

PMID:
9635719
19.

Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.

Meyers M, Wagner MW, Hwang HS, Kinsella TJ, Boothman DA.

Cancer Res. 2001 Jul 1;61(13):5193-201.

20.

Cell-cycle arrest and p53-independent induction of apoptosis in vitro by the new anticancer drugs 5-FdUrd-P-FdCydOct and dCydPam-P-FdUrd in DU-145 human prostate cancer cells.

Cattaneo-Pangrazzi RM, Schott H, Wunderli-Allenspach H, Rothen-Rutishauser B, Guenthert M, Schwendener RA.

J Cancer Res Clin Oncol. 2000 May;126(5):247-56.

PMID:
10815759

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