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Items: 1 to 20 of 129

1.

Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.

Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, Rosenbaum M, Zhao Y, Gu W, Farmer SR, Accili D.

Cell. 2012 Aug 3;150(3):620-32. doi: 10.1016/j.cell.2012.06.027.

2.

C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists.

Vernochet C, Peres SB, Davis KE, McDonald ME, Qiang L, Wang H, Scherer PE, Farmer SR.

Mol Cell Biol. 2009 Sep;29(17):4714-28. doi: 10.1128/MCB.01899-08. Epub 2009 Jun 29.

3.

GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice.

Coelho MS, de Lima CL, Royer C, Silva JB, Oliveira FC, Christ CG, Pereira SA, Bao SN, Lima MC, Pitta MG, Pitta IR, Neves FA, Amato AA.

PLoS One. 2016 May 3;11(5):e0154310. doi: 10.1371/journal.pone.0154310. eCollection 2016.

4.

Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1+ Adipocytes.

Wang H, Liu L, Lin JZ, Aprahamian TR, Farmer SR.

Cell Metab. 2016 Dec 13;24(6):835-847. doi: 10.1016/j.cmet.2016.10.005.

5.

Peroxisome proliferator-activated receptors-α and -γ, and cAMP-mediated pathways, control retinol-binding protein-4 gene expression in brown adipose tissue.

Rosell M, Hondares E, Iwamoto S, Gonzalez FJ, Wabitsch M, Staels B, Olmos Y, Monsalve M, Giralt M, Iglesias R, Villarroya F.

Endocrinology. 2012 Mar;153(3):1162-73. doi: 10.1210/en.2011-1367. Epub 2012 Jan 17.

PMID:
22253419
6.

PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.

Ohno H, Shinoda K, Spiegelman BM, Kajimura S.

Cell Metab. 2012 Mar 7;15(3):395-404. doi: 10.1016/j.cmet.2012.01.019.

7.

Differentiation and characterization in primary culture of white adipose tissue brown adipocyte-like cells.

Lehr L, Canola K, Léger B, Giacobino JP.

Int J Obes (Lond). 2009 Jun;33(6):680-6. doi: 10.1038/ijo.2009.46. Epub 2009 Mar 10.

PMID:
19274054
8.

MiR-27 orchestrates the transcriptional regulation of brown adipogenesis.

Sun L, Trajkovski M.

Metabolism. 2014 Feb;63(2):272-82. doi: 10.1016/j.metabol.2013.10.004. Epub 2013 Oct 24.

PMID:
24238035
9.

Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet.

Andrade JM, Frade AC, Guimarães JB, Freitas KM, Lopes MT, Guimarães AL, de Paula AM, Coimbra CC, Santos SH.

Eur J Nutr. 2014 Oct;53(7):1503-10. doi: 10.1007/s00394-014-0655-6. Epub 2014 Jan 28.

PMID:
24468941
10.

Acetylation-defective mutant of Pparγ is associated with decreased lipid synthesis in breast cancer cells.

Tian L, Wang C, Hagen FK, Gormley M, Addya S, Soccio R, Casimiro MC, Zhou J, Powell MJ, Xu P, Deng H, Sauve AA, Pestell RG.

Oncotarget. 2014 Sep 15;5(17):7303-15.

11.

TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue.

Baskaran P, Krishnan V, Fettel K, Gao P, Zhu Z, Ren J, Thyagarajan B.

Int J Obes (Lond). 2017 May;41(5):739-749. doi: 10.1038/ijo.2017.16. Epub 2017 Jan 20.

12.

Brown vs white adipocytes: the PPARgamma coregulator story.

Koppen A, Kalkhoven E.

FEBS Lett. 2010 Aug 4;584(15):3250-9. doi: 10.1016/j.febslet.2010.06.035. Epub 2010 Jun 30. Review.

13.

Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat.

Lin JZ, Martagón AJ, Cimini SL, Gonzalez DD, Tinkey DW, Biter A, Baxter JD, Webb P, Gustafsson JÅ, Hartig SM, Phillips KJ.

Cell Rep. 2015 Nov 24;13(8):1528-37. doi: 10.1016/j.celrep.2015.10.022. Epub 2015 Nov 12.

14.

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis.

Qian SW, Tang Y, Li X, Liu Y, Zhang YY, Huang HY, Xue RD, Yu HY, Guo L, Gao HD, Liu Y, Sun X, Li YM, Jia WP, Tang QQ.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):E798-807. doi: 10.1073/pnas.1215236110. Epub 2013 Feb 6.

16.

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.

Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR.

Nature. 2008 Aug 21;454(7207):1000-4. doi: 10.1038/nature07221.

17.

The formation of brown adipose tissue induced by transgenic over-expression of PPARγ2.

Zhou Y, Yang J, Huang J, Li T, Xu D, Zuo B, Hou L, Wu W, Zhang L, Xia X, Ma Z, Ren Z, Xiong Y.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):959-64. doi: 10.1016/j.bbrc.2014.03.033. Epub 2014 Mar 15.

PMID:
24642257
18.

Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.

Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P.

Cell Metab. 2013 Mar 5;17(3):423-35. doi: 10.1016/j.cmet.2013.01.016.

19.

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue.

Kiefer FW, Vernochet C, O'Brien P, Spoerl S, Brown JD, Nallamshetty S, Zeyda M, Stulnig TM, Cohen DE, Kahn CR, Plutzky J.

Nat Med. 2012 Jun;18(6):918-25. doi: 10.1038/nm.2757.

20.

IEX-1 deficiency induces browning of white adipose tissue and resists diet-induced obesity.

Shahid M, Javed AA, Chandra D, Ramsey HE, Shah D, Khan MF, Zhao L, Wu MX.

Sci Rep. 2016 Apr 11;6:24135. doi: 10.1038/srep24135.

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